These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 17726094)

  • 1. Enhanced subunit interactions with gemcitabine-5'-diphosphate inhibit ribonucleotide reductases.
    Wang J; Lohman GJ; Stubbe J
    Proc Natl Acad Sci U S A; 2007 Sep; 104(36):14324-9. PubMed ID: 17726094
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphate.
    van der Donk WA; Yu G; Pérez L; Sanchez RJ; Stubbe J; Samano V; Robins MJ
    Biochemistry; 1998 May; 37(18):6419-26. PubMed ID: 9572859
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphate.
    Wang J; Lohman GJ; Stubbe J
    Biochemistry; 2009 Dec; 48(49):11612-21. PubMed ID: 19899807
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant.
    Artin E; Wang J; Lohman GJ; Yokoyama K; Yu G; Griffin RG; Bar G; Stubbe J
    Biochemistry; 2009 Dec; 48(49):11622-9. PubMed ID: 19899770
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutamate 52-β at the α/β subunit interface of
    Lin Q; Parker MJ; Taguchi AT; Ravichandran K; Kim A; Kang G; Shao J; Drennan CL; Stubbe J
    J Biol Chem; 2017 Jun; 292(22):9229-9239. PubMed ID: 28377505
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of an oligomeric interface prevents allosteric inhibition of
    Chen PY; Funk MA; Brignole EJ; Drennan CL
    J Biol Chem; 2018 Jun; 293(26):10404-10412. PubMed ID: 29700111
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.
    Xu H; Faber C; Uchiki T; Racca J; Dealwis C
    Proc Natl Acad Sci U S A; 2006 Mar; 103(11):4028-33. PubMed ID: 16537480
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase.
    Zipse H; Artin E; Wnuk S; Lohman GJ; Martino D; Griffin RG; Kacprzak S; Kaupp M; Hoffman B; Bennati M; Stubbe J; Lees N
    J Am Chem Soc; 2009 Jan; 131(1):200-11. PubMed ID: 19128178
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Subunit Interaction Dynamics of Class Ia Ribonucleotide Reductases: In Search of a Robust Assay.
    Ravichandran K; Olshansky L; Nocera DG; Stubbe J
    Biochemistry; 2020 Apr; 59(14):1442-1453. PubMed ID: 32186371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Uncoupling of allosteric and oligomeric regulation in a functional hybrid enzyme constructed from Escherichia coli and human ribonucleotide reductase.
    Fu Y; Long MJ; Rigney M; Parvez S; Blessing WA; Aye Y
    Biochemistry; 2013 Oct; 52(40):7050-9. PubMed ID: 24024562
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reversible, long-range radical transfer in E. coli class Ia ribonucleotide reductase.
    Minnihan EC; Nocera DG; Stubbe J
    Acc Chem Res; 2013 Nov; 46(11):2524-35. PubMed ID: 23730940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NrdI, a flavodoxin involved in maintenance of the diferric-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase.
    Cotruvo JA; Stubbe J
    Proc Natl Acad Sci U S A; 2008 Sep; 105(38):14383-8. PubMed ID: 18799738
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: covalent modification.
    Lohman GJ; Stubbe J
    Biochemistry; 2010 Feb; 49(7):1404-17. PubMed ID: 20088569
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ribonucleotide Reductases: Structure, Chemistry, and Metabolism Suggest New Therapeutic Targets.
    Greene BL; Kang G; Cui C; Bennati M; Nocera DG; Drennan CL; Stubbe J
    Annu Rev Biochem; 2020 Jun; 89():45-75. PubMed ID: 32569524
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism for ribonucleotide reductase inactivation by the anticancer drug gemcitabine.
    Pereira S; Fernandes PA; Ramos MJ
    J Comput Chem; 2004 Jul; 25(10):1286-94. PubMed ID: 15139041
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High-field EPR detection of a disulfide radical anion in the reduction of cytidine 5'-diphosphate by the E441Q R1 mutant of Escherichia coli ribonucleotide reductase.
    Lawrence CC; Bennati M; Obias HV; Bar G; Griffin RG; Stubbe J
    Proc Natl Acad Sci U S A; 1999 Aug; 96(16):8979-84. PubMed ID: 10430881
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein engineering a PhotoRNR chimera based on a unifying evolutionary apparatus among the natural classes of ribonucleotide reductases.
    Song DY; Stubbe J; Nocera DG
    Proc Natl Acad Sci U S A; 2024 Apr; 121(18):e2317291121. PubMed ID: 38648489
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of the nitrogen-centered radical formed during inactivation of E. coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine-5'-diphosphate: trapping of the 3'-ketonucleotide.
    Fritscher J; Artin E; Wnuk S; Bar G; Robblee JH; Kacprzak S; Kaupp M; Griffin RG; Bennati M; Stubbe J
    J Am Chem Soc; 2005 Jun; 127(21):7729-38. PubMed ID: 15913363
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A rare combination of ribonucleotide reductases in the social amoeba Dictyostelium discoideum.
    Crona M; Avesson L; Sahlin M; Lundin D; Hinas A; Klose R; Söderbom F; Sjöberg BM
    J Biol Chem; 2013 Mar; 288(12):8198-8208. PubMed ID: 23372162
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation.
    Seyedsayamdost MR; Xie J; Chan CT; Schultz PG; Stubbe J
    J Am Chem Soc; 2007 Dec; 129(48):15060-71. PubMed ID: 17990884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.