BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

743 related articles for article (PubMed ID: 17727268)

  • 1. Design of new plasmepsin inhibitors: a virtual high throughput screening approach on the EGEE grid.
    Kasam V; Zimmermann M; Maass A; Schwichtenberg H; Wolf A; Jacq N; Breton V; Hofmann-Apitius M
    J Chem Inf Model; 2007; 47(5):1818-28. PubMed ID: 17727268
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Computer-aided design and synthesis of nonpeptidic plasmepsin II and IV inhibitors.
    Luksch T; Chan NS; Brass S; Sotriffer CA; Klebe G; Diederich WE
    ChemMedChem; 2008 Sep; 3(9):1323-36. PubMed ID: 18752222
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and discovery of plasmepsin II inhibitors using an automated workflow on large-scale grids.
    Degliesposti G; Kasam V; Da Costa A; Kang HK; Kim N; Kim DW; Breton V; Kim D; Rastelli G
    ChemMedChem; 2009 Jul; 4(7):1164-73. PubMed ID: 19437467
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II.
    Muthas D; Nöteberg D; Sabnis YA; Hamelink E; Vrang L; Samuelsson B; Karlén A; Hallberg A
    Bioorg Med Chem; 2005 Sep; 13(18):5371-90. PubMed ID: 16054370
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational analysis of plasmepsin IV bound to an allophenylnorstatine inhibitor.
    Gutiérrez-de-Terán H; Nervall M; Dunn BM; Clemente JC; Aqvist J
    FEBS Lett; 2006 Oct; 580(25):5910-6. PubMed ID: 17045991
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of plasmepsin inhibitors by fragment-based docking and consensus scoring.
    Friedman R; Caflisch A
    ChemMedChem; 2009 Aug; 4(8):1317-26. PubMed ID: 19472268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Predicting functional residues in Plasmodium falciparum plasmepsins by combining sequence and structural analysis with molecular dynamics simulations.
    Valiente PA; Batista PR; Pupo A; Pons T; Valencia A; Pascutti PG
    Proteins; 2008 Nov; 73(2):440-57. PubMed ID: 18442137
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Plasmepsins as potential targets for new antimalarial therapy.
    Ersmark K; Samuelsson B; Hallberg A
    Med Res Rev; 2006 Sep; 26(5):626-66. PubMed ID: 16838300
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of Plasmepsin II-potential antimalarial agents.
    Corminboeuf O; Dunet G; Hafsi M; Grimont J; Grisostomi C; Meyer S; Binkert C; Bur D; Jones A; Prade L; Brun R; Boss C
    Bioorg Med Chem Lett; 2006 Dec; 16(24):6194-9. PubMed ID: 17000102
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ligand-based virtual screening and in silico design of new antimalarial compounds using nonstochastic and stochastic total and atom-type quadratic maps.
    Marrero-Ponce Y; Iyarreta-Veitía M; Montero-Torres A; Romero-Zaldivar C; Brandt CA; Avila PE; Kirchgatter K; Machado Y
    J Chem Inf Model; 2005; 45(4):1082-100. PubMed ID: 16045304
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New class of small nonpeptidyl compounds blocks Plasmodium falciparum development in vitro by inhibiting plasmepsins.
    Jiang S; Prigge ST; Wei L; Gao Ye ; Hudson TH; Gerena L; Dame JB; Kyle DE
    Antimicrob Agents Chemother; 2001 Sep; 45(9):2577-84. PubMed ID: 11502532
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Computation-based virtual screening for designing novel antimalarial drugs by targeting falcipain-III: a structure-based drug designing approach.
    Kesharwani RK; Singh DV; Misra K
    J Vector Borne Dis; 2013; 50(2):93-102. PubMed ID: 23995310
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterisation of hydrazides and hydrazine derivatives as novel aspartic protease inhibitors.
    Ahmed W; Rani M; Khan IA; Iqbal A; Khan KM; Haleem MA; Azim MK
    J Enzyme Inhib Med Chem; 2010 Oct; 25(5):673-8. PubMed ID: 20063996
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of acridinyl hydrazides as potent aspartic protease inhibitors.
    Azim MK; Ahmed W; Khan IA; Rao NA; Khan KM
    Bioorg Med Chem Lett; 2008 May; 18(9):3011-5. PubMed ID: 18417344
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Plasmodium falciparum, P. vivax, and P. malariae: a comparison of the active site properties of plasmepsins cloned and expressed from three different species of the malaria parasite.
    Westling J; Yowell CA; Majer P; Erickson JW; Dame JB; Dunn BM
    Exp Parasitol; 1997 Nov; 87(3):185-93. PubMed ID: 9371083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Plasmodium falciparum: new molecular targets with potential for antimalarial drug development.
    Gardiner DL; Skinner-Adams TS; Brown CL; Andrews KT; Stack CM; McCarthy JS; Dalton JP; Trenholme KR
    Expert Rev Anti Infect Ther; 2009 Nov; 7(9):1087-98. PubMed ID: 19883329
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A heterogeneous enzymatic assay for quantification of Plasmepsin II activity and the evaluation of its inhibitors.
    Salas E; Ramírez A; Otero-Bilbao A; Vázquez R; Reyes O; Mendiola J; Duarte CA; Otero-González A; Gutiérrez OA; Chávez MA
    J Pharm Biomed Anal; 2004 Mar; 34(4):833-40. PubMed ID: 15019062
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries.
    Beyer BB; Johnson JV; Chung AY; Li T; Madabushi A; Agbandje-McKenna M; McKenna R; Dame JB; Dunn BM
    Biochemistry; 2005 Feb; 44(6):1768-79. PubMed ID: 15697202
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design of inhibitors against HIV, HTLV-I, and Plasmodium falciparum aspartic proteases.
    Abdel-Rahman HM; Kimura T; Hidaka K; Kiso A; Nezami A; Freire E; Hayashi Y; Kiso Y
    Biol Chem; 2004 Nov; 385(11):1035-9. PubMed ID: 15576323
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of plasmepsin I and plasmepsin II inhibitors with activity in Plasmodium falciparum-infected cultured human erythrocytes.
    Nöteberg D; Hamelink E; Hultén J; Wahlgren M; Vrang L; Samuelsson B; Hallberg A
    J Med Chem; 2003 Feb; 46(5):734-46. PubMed ID: 12593654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.