BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 17760968)

  • 1. Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study.
    Le Maitre CL; Hoyland JA; Freemont AJ
    Arthritis Res Ther; 2007; 9(4):R83. PubMed ID: 17760968
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration.
    Le Maitre CL; Freemont AJ; Hoyland JA
    Int J Exp Pathol; 2006 Feb; 87(1):17-28. PubMed ID: 16436110
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc.
    Hoyland JA; Le Maitre C; Freemont AJ
    Rheumatology (Oxford); 2008 Jun; 47(6):809-14. PubMed ID: 18397957
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile.
    Le Maitre CL; Hoyland JA; Freemont AJ
    Arthritis Res Ther; 2007; 9(4):R77. PubMed ID: 17688691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration.
    Le Maitre CL; Freemont AJ; Hoyland JA
    Arthritis Res Ther; 2005; 7(4):R732-45. PubMed ID: 15987475
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration.
    Phillips KL; Jordan-Mahy N; Nicklin MJ; Le Maitre CL
    Ann Rheum Dis; 2013 Nov; 72(11):1860-7. PubMed ID: 23396662
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of proteinase-activated receptor-2 in the intervertebral disc.
    Iida R; Akeda K; Kasai Y; Masuda K; Morimoto R; Sakakibara T; Sato M; Uchida A
    Spine (Phila Pa 1976); 2009 Mar; 34(5):470-8. PubMed ID: 19247167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytokine Inhibitors Upregulate Extracellular Matrix Anabolism of Human Intervertebral Discs under Alginate Beads and Alginate-Embedded Explant Cultures.
    Kakutani K; Yurube T; An HS; Doita M; Masuda K
    Int J Mol Sci; 2023 Aug; 24(15):. PubMed ID: 37569715
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells.
    Le Maitre CL; Freemont AJ; Hoyland JA
    Arthritis Res Ther; 2009; 11(5):R137. PubMed ID: 19754961
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IL-20 may contribute to the pathogenesis of human intervertebral disc herniation.
    Huang KY; Lin RM; Chen WY; Lee CL; Yan JJ; Chang MS
    Spine (Phila Pa 1976); 2008 Sep; 33(19):2034-40. PubMed ID: 18758357
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration.
    Le Maitre CL; Freemont AJ; Hoyland JA
    Arthritis Res Ther; 2007; 9(3):R45. PubMed ID: 17498290
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption.
    Weiler C; Nerlich AG; Zipperer J; Bachmeier BE; Boos N
    Eur Spine J; 2002 Aug; 11(4):308-20. PubMed ID: 12193991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of interleukin-17A in nucleus pulposus cells and its small-molecule inhibitors for intervertebral disc disease.
    Suyama K; Sakai D; Hirayama N; Nakamura Y; Matsushita E; Terayama H; Qu N; Tanaka O; Sakabe K; Watanabe M
    J Cell Mol Med; 2018 Nov; 22(11):5539-5551. PubMed ID: 30207057
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic and functional studies of the intervertebral disc: a novel murine intervertebral disc model.
    Pelle DW; Peacock JD; Schmidt CL; Kampfschulte K; Scholten DJ; Russo SS; Easton KJ; Steensma MR
    PLoS One; 2014; 9(12):e112454. PubMed ID: 25474689
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc.
    Purmessur D; Freemont AJ; Hoyland JA
    Arthritis Res Ther; 2008; 10(4):R99. PubMed ID: 18727839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Matrix synthesis and degradation in human intervertebral disc degeneration.
    Le Maitre CL; Pockert A; Buttle DJ; Freemont AJ; Hoyland JA
    Biochem Soc Trans; 2007 Aug; 35(Pt 4):652-5. PubMed ID: 17635113
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Matrix metalloproteinases and aggrecanase: their role in disorders of the human intervertebral disc.
    Roberts S; Caterson B; Menage J; Evans EH; Jaffray DC; Eisenstein SM
    Spine (Phila Pa 1976); 2000 Dec; 25(23):3005-13. PubMed ID: 11145811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc.
    Richardson SM; Doyle P; Minogue BM; Gnanalingham K; Hoyland JA
    Arthritis Res Ther; 2009; 11(4):R126. PubMed ID: 19695094
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inflammatory profiles in canine intervertebral disc degeneration.
    Willems N; Tellegen AR; Bergknut N; Creemers LB; Wolfswinkel J; Freudigmann C; Benz K; Grinwis GC; Tryfonidou MA; Meij BP
    BMC Vet Res; 2016 Jan; 12():10. PubMed ID: 26757881
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IL-1Ra deficiency accelerates intervertebral disc degeneration in C57BL6J mice.
    Swamy G; Salo P; Duncan N; Jirik F; Matyas J
    JOR Spine; 2022 Jun; 5(2):e1201. PubMed ID: 35783913
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.