BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 17762173)

  • 21. 8-cyclopentyl-1,3-dipropylxanthine and other xanthines differentially bind to the wild-type and delta F508 first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator.
    Cohen BE; Lee G; Jacobson KA; Kim YC; Huang Z; Sorscher EJ; Pollard HB
    Biochemistry; 1997 May; 36(21):6455-61. PubMed ID: 9174362
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells.
    Egan ME; Glöckner-Pagel J; Ambrose C; Cahill PA; Pappoe L; Balamuth N; Cho E; Canny S; Wagner CA; Geibel J; Caplan MJ
    Nat Med; 2002 May; 8(5):485-92. PubMed ID: 11984593
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A mouse model for the delta F508 allele of cystic fibrosis.
    Zeiher BG; Eichwald E; Zabner J; Smith JJ; Puga AP; McCray PB; Capecchi MR; Welsh MJ; Thomas KR
    J Clin Invest; 1995 Oct; 96(4):2051-64. PubMed ID: 7560099
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of revertants for the cystic fibrosis delta F508 mutation using STE6-CFTR chimeras in yeast.
    Teem JL; Berger HA; Ostedgaard LS; Rich DP; Tsui LC; Welsh MJ
    Cell; 1993 Apr; 73(2):335-46. PubMed ID: 7682896
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR.
    Du K; Sharma M; Lukacs GL
    Nat Struct Mol Biol; 2005 Jan; 12(1):17-25. PubMed ID: 15619635
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers.
    LeSimple P; Liao J; Robert R; Gruenert DC; Hanrahan JW
    J Physiol; 2010 Apr; 588(Pt 8):1195-209. PubMed ID: 20156845
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator.
    Younger JM; Chen L; Ren HY; Rosser MF; Turnbull EL; Fan CY; Patterson C; Cyr DM
    Cell; 2006 Aug; 126(3):571-82. PubMed ID: 16901789
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Normal function of the cystic fibrosis conductance regulator protein can be associated with homozygous (Delta)F508 mutation.
    Sermet-Gaudelus I; Vallée B; Urbin I; Torossi T; Marianovski R; Fajac A; Feuillet MN; Bresson JL; Lenoir G; Bernaudin JF; Edelman A
    Pediatr Res; 2002 Nov; 52(5):628-35. PubMed ID: 12409506
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Introduction of the most common cystic fibrosis mutation (Delta F508) into human P-glycoprotein disrupts packing of the transmembrane segments.
    Loo TW; Bartlett MC; Clarke DM
    J Biol Chem; 2002 Aug; 277(31):27585-8. PubMed ID: 12070134
    [TBL] [Abstract][Full Text] [Related]  

  • 30. In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant deltaF508 in murine nasal epithelium.
    Kelley TJ; Thomas K; Milgram LJ; Drumm ML
    Proc Natl Acad Sci U S A; 1997 Mar; 94(6):2604-8. PubMed ID: 9122242
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cysteine string protein monitors late steps in cystic fibrosis transmembrane conductance regulator biogenesis.
    Zhang H; Schmidt BZ; Sun F; Condliffe SB; Butterworth MB; Youker RT; Brodsky JL; Aridor M; Frizzell RA
    J Biol Chem; 2006 Apr; 281(16):11312-21. PubMed ID: 16469739
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Ultrastructural localization of variant forms of cystic fibrosis transmembrane conductance regulator in human bronchial epithelial of xenografts.
    Yang Y; Engelhardt JF; Wilson JM
    Am J Respir Cell Mol Biol; 1994 Jul; 11(1):7-15. PubMed ID: 7517144
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effects of the delta F508 mutation on the structure, function, and folding of the first nucleotide-binding domain of CFTR.
    Thomas PJ; Pedersen PL
    J Bioenerg Biomembr; 1993 Feb; 25(1):11-9. PubMed ID: 7680027
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Protection against bronchial asthma by CFTR delta F508 mutation: a heterozygote advantage in cystic fibrosis.
    Schroeder SA; Gaughan DM; Swift M
    Nat Med; 1995 Jul; 1(7):703-5. PubMed ID: 7585155
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Strategies for correcting the delta F508 CFTR protein-folding defect.
    Brown CR; Hong-Brown LQ; Welch WJ
    J Bioenerg Biomembr; 1997 Oct; 29(5):491-502. PubMed ID: 9511934
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Delta F508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells.
    Heda GD; Tanwani M; Marino CR
    Am J Physiol Cell Physiol; 2001 Jan; 280(1):C166-74. PubMed ID: 11121388
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.
    Sato S; Ward CL; Krouse ME; Wine JJ; Kopito RR
    J Biol Chem; 1996 Jan; 271(2):635-8. PubMed ID: 8557666
    [TBL] [Abstract][Full Text] [Related]  

  • 38. [Frequency of mutations and genotypes of the CFTR gene in cystic fibrosis adults in Poland].
    Witt M; Pogorzelski A; Bal J; Rutkiewicz E; Majka L; Sobczyńska A
    Pneumonol Alergol Pol; 1999; 67(3-4):137-41. PubMed ID: 10497446
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Assembly and misassembly of cystic fibrosis transmembrane conductance regulator: folding defects caused by deletion of F508 occur before and after the calnexin-dependent association of membrane spanning domain (MSD) 1 and MSD2.
    Rosser MF; Grove DE; Chen L; Cyr DM
    Mol Biol Cell; 2008 Nov; 19(11):4570-9. PubMed ID: 18716059
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Post-translational disruption of the delta F508 cystic fibrosis transmembrane conductance regulator (CFTR)-molecular chaperone complex with geldanamycin stabilizes delta F508 CFTR in the rabbit reticulocyte lysate.
    Fuller W; Cuthbert AW
    J Biol Chem; 2000 Dec; 275(48):37462-8. PubMed ID: 10982807
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.