BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 17766838)

  • 1. A platelet biomarker for assessing phosphoinositide 3-kinase inhibition during cancer chemotherapy.
    Bowers RK; Marder P; Green LJ; Horn CL; Faber AL; Thomas JE
    Mol Cancer Ther; 2007 Sep; 6(9):2600-7. PubMed ID: 17766838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inflammatory cytokine TSLP stimulates platelet secretion and potentiates platelet aggregation via a TSLPR-dependent PI3K/Akt signaling pathway.
    Dong J; Lin J; Wang B; He S; Wu C; Kushwaha KK; Mohabeer N; Su Y; Fang H; Huang K; Li D
    Cell Physiol Biochem; 2015; 35(1):160-74. PubMed ID: 25591759
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B.
    Lova P; Paganini S; Hirsch E; Barberis L; Wymann M; Sinigaglia F; Balduini C; Torti M
    J Biol Chem; 2003 Jan; 278(1):131-8. PubMed ID: 12407113
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lipid products of phosphoinositide 3-kinase and phosphatidylinositol 4',5'-bisphosphate are both required for ADP-dependent platelet spreading.
    Heraud JM; Racaud-Sultan C; Gironcel D; Albigès-Rizo C; Giacomini T; Roques S; Martel V; Breton-Douillon M; Perret B; Chap H
    J Biol Chem; 1998 Jul; 273(28):17817-23. PubMed ID: 9651384
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Platelet-derived-growth-factor-induced signalling in human platelets: phosphoinositide-3-kinase-dependent inhibition of platelet activation.
    Selheim F; Fukami MH; Holmsen H; Vassbotn FS
    Biochem J; 2000 Sep; 350 Pt 2(Pt 2):469-75. PubMed ID: 10947961
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphatidylinositol 3,4,5-trisphosphate-dependent stimulation of phospholipase C-gamma2 is an early key event in FcgammaRIIA-mediated activation of human platelets.
    Gratacap MP; Payrastre B; Viala C; Mauco G; Plantavid M; Chap H
    J Biol Chem; 1998 Sep; 273(38):24314-21. PubMed ID: 9733717
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation.
    Kovacsovics TJ; Bachelot C; Toker A; Vlahos CJ; Duckworth B; Cantley LC; Hartwig JH
    J Biol Chem; 1995 May; 270(19):11358-66. PubMed ID: 7744773
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The P2Y(12) receptor induces platelet aggregation through weak activation of the alpha(IIb)beta(3) integrin--a phosphoinositide 3-kinase-dependent mechanism.
    Kauffenstein G; Bergmeier W; Eckly A; Ohlmann P; Léon C; Cazenave JP; Nieswandt B; Gachet C
    FEBS Lett; 2001 Sep; 505(2):281-90. PubMed ID: 11566191
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of phosphoinositide 3-kinase, LY294002 and wortmannin, affect sperm capacitation and associated phosphorylation of proteins differently: Ca2+-dependent divergences.
    Nauc V; De Lamirande E; Leclerc P; Gagnon C
    J Androl; 2004; 25(4):573-85. PubMed ID: 15223846
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin.
    Adi S; Wu NY; Rosenthal SM
    Endocrinology; 2001 Jan; 142(1):498-501. PubMed ID: 11145615
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphoinositide 3-kinase inhibition reverses platelet aggregation triggered by the combination of the neutrophil proteinases elastase and cathepsin G without impairing alpha(IIb)beta(3) integrin activation.
    Trumel C; Si-Tahar M; Balloy V; Chignard M; Chap H; Payrastre B; Plantavid M; Pidard D
    FEBS Lett; 2000 Nov; 484(3):184-8. PubMed ID: 11078875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of phosphatidylinositol-3 kinase and its association with Gab1 in thrombopoietin-mediated up-regulation of platelet function.
    Kojima H; Shinagawa A; Shimizu S; Kanada H; Hibi M; Hirano T; Nagasawa T
    Exp Hematol; 2001 May; 29(5):616-22. PubMed ID: 11376875
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositides are required for store-mediated calcium entry in human platelets.
    Rosado JA; Sage SO
    J Biol Chem; 2000 Mar; 275(13):9110-3. PubMed ID: 10734043
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The p85 and p110 subunits of phosphatidylinositol 3-kinase-alpha are substrates, in vitro, for a constitutively associated protein tyrosine kinase in platelets.
    Geltz NR; Augustine JA
    Blood; 1998 Feb; 91(3):930-9. PubMed ID: 9446654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of the phosphatidylinositol 3'-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo.
    Bondar VM; Sweeney-Gotsch B; Andreeff M; Mills GB; McConkey DJ
    Mol Cancer Ther; 2002 Oct; 1(12):989-97. PubMed ID: 12481421
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A collagen-related peptide regulates phospholipase Cgamma2 via phosphatidylinositol 3-kinase in human platelets.
    Pasquet JM; Bobe R; Gross B; Gratacap MP; Tomlinson MG; Payrastre B; Watson SP
    Biochem J; 1999 Aug; 342 ( Pt 1)(Pt 1):171-7. PubMed ID: 10432314
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinct Ca2+ requirement for NO production between proteinase-activated receptor 1 and 4 (PAR1 and PAR4) in vascular endothelial cells.
    Hirano K; Nomoto N; Hirano M; Momota F; Hanada A; Kanaide H
    J Pharmacol Exp Ther; 2007 Aug; 322(2):668-77. PubMed ID: 17494865
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Integrin alpha IIb beta 3-mediated pp125FAK phosphorylation and platelet spreading on fibrinogen are regulated by PI 3-kinase.
    Ji P; Haimovich B
    Biochim Biophys Acta; 1999 Jan; 1448(3):543-52. PubMed ID: 9990307
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
    Hou L; Klann E
    J Neurosci; 2004 Jul; 24(28):6352-61. PubMed ID: 15254091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Homotypic gap junctional communication associated with metastasis suppression increases with PKA activity and is unaffected by PI3K inhibition.
    Bodenstine TM; Vaidya KS; Ismail A; Beck BH; Cook LM; Diers AR; Landar A; Welch DR
    Cancer Res; 2010 Dec; 70(23):10002-11. PubMed ID: 21098703
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.