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2. A novel, sensitive assay for O6-methyl- and O6-ethylguanine in DNA, based on repair by the enzyme O6-alkylguanine-DNA-alkyltransferase in competition with an oligonucleotide containing O6-methylguanine. Souliotis VL; Kyrtopoulos SA Cancer Res; 1989 Dec; 49(24 Pt 1):6997-7001. PubMed ID: 2684406 [TBL] [Abstract][Full Text] [Related]
3. Depletion of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine in three-dimensional collagen cultures of normal human breast epithelial cells. Hamdan MA; Guzman RC; Yang J; Beattie C; Mascharack P; Nandi S Carcinogenesis; 1992 Oct; 13(10):1743-9. PubMed ID: 1423833 [TBL] [Abstract][Full Text] [Related]
4. Formation and persistence of O6-ethylguanine in genomic and transgene DNA in liver and brain of lambda(lacZ) transgenic mice treated with N-ethyl-N-nitrosourea. Mientjes EJ; Hochleitner K; Luiten-Schuite A; van Delft JH; Thomale J; Berends F; Rajewsky MF; Lohman PH; Baan RA Carcinogenesis; 1996 Nov; 17(11):2449-54. PubMed ID: 8968062 [TBL] [Abstract][Full Text] [Related]
5. Relevance of environmental alkylating agents to repair protein O6-alkylguanine-DNA alkyltransferase: determination of individual and collective repair capacities of O6-methylguanine. Oesch F; Klein S Cancer Res; 1992 Apr; 52(7):1801-3. PubMed ID: 1532345 [TBL] [Abstract][Full Text] [Related]
6. Monoclonal antibody-based immunoassay for the determination of cellular enzymatic activity for repair of specific carcinogen-DNA adducts (O6-alkylguanine). Nehls P; Rajewsky MF Carcinogenesis; 1990 Jan; 11(1):81-7. PubMed ID: 2295129 [TBL] [Abstract][Full Text] [Related]
7. Efficient repair of O6-ethylguanine, but not O4-ethylthymine or O2-ethylthymine, is dependent upon O6-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells. Bronstein SM; Skopek TR; Swenberg JA Cancer Res; 1992 Apr; 52(7):2008-11. PubMed ID: 1551130 [TBL] [Abstract][Full Text] [Related]
8. Heterogeneity of O6-alkylguanine-DNA-alkyltransferase measured by flow cytometric analysis in blood and bone marrow mononuclear cells. Liu L; Lee K; Schupp J; KoƧ ON; Gerson SL Clin Cancer Res; 1998 Feb; 4(2):475-81. PubMed ID: 9516939 [TBL] [Abstract][Full Text] [Related]
9. Reduction of O6-alkylguanine-DNA alkyltransferase activity in HeLa cells treated with O6-alkylguanines. Dolan ME; Morimoto K; Pegg AE Cancer Res; 1985 Dec; 45(12 Pt 1):6413-7. PubMed ID: 4063990 [TBL] [Abstract][Full Text] [Related]
10. Differential effects of procarbazine and methylnitrosourea on the accumulation of O6-methylguanine and the depletion and recovery of O6-alkylguanine-DNA alkyltransferase in rat tissues. Valavanis C; Souliotis VL; Kyrtopoulos SA Carcinogenesis; 1994 Aug; 15(8):1681-8. PubMed ID: 7519972 [TBL] [Abstract][Full Text] [Related]
11. Specific labeling of O6-alkylguanine-DNA alkyltransferase by reaction with O6-(p-hydroxy[3H]methylbenzyl)guanine. Ciocco GM; Moschel RC; Chae MY; McLaughlin PJ; Zagon IS; Pegg AE Cancer Res; 1995 Sep; 55(18):4085-91. PubMed ID: 7664284 [TBL] [Abstract][Full Text] [Related]
12. Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene. Dumenco LL; Arce C; Norton K; Yun J; Wagner T; Gerson SL Cancer Res; 1991 Jul; 51(13):3391-8. PubMed ID: 2054779 [TBL] [Abstract][Full Text] [Related]
13. Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate. Dolan ME; Pegg AE; Hora NK; Erickson LC Cancer Res; 1988 Jul; 48(13):3603-6. PubMed ID: 2837318 [TBL] [Abstract][Full Text] [Related]
14. Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents. Dolan ME; Norbeck L; Clyde C; Hora NK; Erickson LC; Pegg AE Carcinogenesis; 1989 Sep; 10(9):1613-9. PubMed ID: 2766456 [TBL] [Abstract][Full Text] [Related]
15. Repair of synthetic oligonucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine, by O6-alkylguanine-DNA alkyltransferase. Graves RJ; Li BF; Swann PF IARC Sci Publ; 1987; (84):41-3. PubMed ID: 3316001 [TBL] [Abstract][Full Text] [Related]
16. Extent of formation of O4-methylthymidine in calf thymus DNA methylated by N-methyl-N-nitrosourea and lack of repair of this product by rat liver O6-alkylguanine-DNA-alkyltransferase. Dolan ME; Pegg AE Carcinogenesis; 1985 Nov; 6(11):1611-4. PubMed ID: 4053281 [TBL] [Abstract][Full Text] [Related]
17. The role of O6-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects of O6-substituted guanine residues incorporated in codon 12 of the H-ras gene. Bishop RE; Dunn LL; Pauly GT; Dolan ME; Moschel RC Carcinogenesis; 1993 Apr; 14(4):593-8. PubMed ID: 8472320 [TBL] [Abstract][Full Text] [Related]
18. Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine. Kanugula S; Goodtzova K; Edara S; Pegg AE Biochemistry; 1995 May; 34(21):7113-9. PubMed ID: 7766621 [TBL] [Abstract][Full Text] [Related]
19. Studies in gastric carcinogenesis. IV. O6-methylguanine and its repair in normal and atrophic biopsy specimens of human gastric mucosa. Correlation of O6-alkylguanine-DNA alkyltransferase activities in gastric mucosa and circulating lymphocytes. Kyrtopoulos SA; Ampatzi P; Davaris P; Haritopoulos N; Golematis B Carcinogenesis; 1990 Mar; 11(3):431-6. PubMed ID: 2311187 [TBL] [Abstract][Full Text] [Related]
20. Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase. Pegg AE; Scicchitano D; Dolan ME Cancer Res; 1984 Sep; 44(9):3806-11. PubMed ID: 6378375 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]