BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 17785546)

  • 1. Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.
    Molinolo AA; Hewitt SM; Amornphimoltham P; Keelawat S; Rangdaeng S; Meneses García A; Raimondi AR; Jufe R; Itoiz M; Gao Y; Saranath D; Kaleebi GS; Yoo GH; Leak L; Myers EM; Shintani S; Wong D; Massey HD; Yeudall WA; Lonardo F; Ensley J; Gutkind JS
    Clin Cancer Res; 2007 Sep; 13(17):4964-73. PubMed ID: 17785546
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.
    Amornphimoltham P; Patel V; Sodhi A; Nikitakis NG; Sauk JJ; Sausville EA; Molinolo AA; Gutkind JS
    Cancer Res; 2005 Nov; 65(21):9953-61. PubMed ID: 16267020
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway.
    Nathan CO; Amirghahari N; Abreo F; Rong X; Caldito G; Jones ML; Zhou H; Smith M; Kimberly D; Glass J
    Clin Cancer Res; 2004 Sep; 10(17):5820-7. PubMed ID: 15355912
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model.
    Czerninski R; Amornphimoltham P; Patel V; Molinolo AA; Gutkind JS
    Cancer Prev Res (Phila); 2009 Jan; 2(1):27-36. PubMed ID: 19139015
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01.
    Amornphimoltham P; Sriuranpong V; Patel V; Benavides F; Conti CJ; Sauk J; Sausville EA; Molinolo AA; Gutkind JS
    Clin Cancer Res; 2004 Jun; 10(12 Pt 1):4029-37. PubMed ID: 15217935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma.
    Georgy SR; Cangkrama M; Srivastava S; Partridge D; Auden A; Dworkin S; McLean CA; Jane SM; Darido C
    J Natl Cancer Inst; 2015 Sep; 107(9):. PubMed ID: 26063791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Teasing out the best molecular marker in the AKT/mTOR pathway in head and neck squamous cell cancer patients.
    Clark C; Shah S; Herman-Ferdinandez L; Ekshyyan O; Abreo F; Rong X; McLarty J; Lurie A; Milligan EJ; Nathan CO
    Laryngoscope; 2010 Jun; 120(6):1159-65. PubMed ID: 20513033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PI3K/Akt/mTOR axis in head and neck cancer: functions, aberrations, cross-talk, and therapies.
    Vander Broek R; Mohan S; Eytan DF; Chen Z; Van Waes C
    Oral Dis; 2015 Oct; 21(7):815-25. PubMed ID: 24219320
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular-targeted therapies in the treatment of squamous cell carcinomas of the head and neck.
    Le Tourneau C; Siu LL
    Curr Opin Oncol; 2008 May; 20(3):256-63. PubMed ID: 18391623
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting EGFR-PI3K-AKT-mTOR signaling enhances radiosensitivity in head and neck squamous cell carcinoma.
    Horn D; Hess J; Freier K; Hoffmann J; Freudlsperger C
    Expert Opin Ther Targets; 2015 Jun; 19(6):795-805. PubMed ID: 25652792
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.
    Jackson-Bernitsas DG; Ichikawa H; Takada Y; Myers JN; Lin XL; Darnay BG; Chaturvedi MM; Aggarwal BB
    Oncogene; 2007 Mar; 26(10):1385-97. PubMed ID: 16953224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma.
    Squarize CH; Castilho RM; Sriuranpong V; Pinto DS; Gutkind JS
    Neoplasia; 2006 Sep; 8(9):733-46. PubMed ID: 16984731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma.
    Schneider A; Younis RH; Gutkind JS
    Neoplasia; 2008 Nov; 10(11):1295-302. PubMed ID: 18953439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased NBS1 expression is a marker of aggressive head and neck cancer and overexpression of NBS1 contributes to transformation.
    Yang MH; Chiang WC; Chou TY; Chang SY; Chen PM; Teng SC; Wu KJ
    Clin Cancer Res; 2006 Jan; 12(2):507-15. PubMed ID: 16428493
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immunohistochemical expression of the mammalian target of rapamycin pathway in penile squamous cell carcinomas: a tissue microarray study of 112 cases.
    Chaux A; Munari E; Cubilla AL; Hicks J; Lecksell K; Burnett AL; Netto GJ
    Histopathology; 2014 May; 64(6):863-71. PubMed ID: 24279699
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Paradigm of kinase-driven pathway downstream of epidermal growth factor receptor/Akt in human lung carcinomas.
    Dobashi Y; Suzuki S; Kimura M; Matsubara H; Tsubochi H; Imoto I; Ooi A
    Hum Pathol; 2011 Feb; 42(2):214-26. PubMed ID: 21040950
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Spatial relationship of phosphorylated epidermal growth factor receptor and activated AKT in head and neck squamous cell carcinoma.
    Nijkamp MM; Hoogsteen IJ; Span PN; Takes RP; Lok J; Rijken PF; van der Kogel AJ; Bussink J; Kaanders JH
    Radiother Oncol; 2011 Oct; 101(1):165-70. PubMed ID: 21775008
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma.
    Dong G; Chen Z; Li ZY; Yeh NT; Bancroft CC; Van Waes C
    Cancer Res; 2001 Aug; 61(15):5911-8. PubMed ID: 11479233
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Persistent activation of Rac1 in squamous carcinomas of the head and neck: evidence for an EGFR/Vav2 signaling axis involved in cell invasion.
    Patel V; Rosenfeldt HM; Lyons R; Servitja JM; Bustelo XR; Siroff M; Gutkind JS
    Carcinogenesis; 2007 Jun; 28(6):1145-52. PubMed ID: 17234718
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tid1 functions as a tumour suppressor in head and neck squamous cell carcinoma.
    Chen CY; Chiou SH; Huang CY; Jan CI; Lin SC; Hu WY; Chou SH; Liu CJ; Lo JF
    J Pathol; 2009 Nov; 219(3):347-55. PubMed ID: 19681071
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.