173 related articles for article (PubMed ID: 17786622)
1. Comparison of the 17 alpha-hydroxylase/C17,20-lyase activities of porcine, guinea pig and bovine P450c17 using purified recombinant fusion proteins containing P450c17 linked to NADPH-P450 reductase.
Shet MS; Fisher CW; Tremblay Y; Belanger A; Conley AJ; Mason JI; Estabrook RW
Drug Metab Rev; 2007; 39(2-3):289-307. PubMed ID: 17786622
[TBL] [Abstract][Full Text] [Related]
2. NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble microsomal P450 reductase.
Jenkins CM; Waterman MR
Biochemistry; 1998 Apr; 37(17):6106-13. PubMed ID: 9558349
[TBL] [Abstract][Full Text] [Related]
3. Purification and enzymatic properties of a recombinant fusion protein expressed in Escherichia coli containing the domains of bovine P450 17A and rat NADPH-P450 reductase.
Shet MS; Fisher CW; Arlotto MP; Shackleton CH; Holmans PL; Martin-Wixtrom CA; Saeki Y; Estabrook RW
Arch Biochem Biophys; 1994 Jun; 311(2):402-17. PubMed ID: 8203904
[TBL] [Abstract][Full Text] [Related]
4. The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17 alpha-hydroxylation of progesterone and pregnenolone by P450c17.
Shet MS; Fisher CW; Estabrook RW
Arch Biochem Biophys; 1997 Mar; 339(1):218-25. PubMed ID: 9056252
[TBL] [Abstract][Full Text] [Related]
5. Expression and purification of functional human 17 alpha-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. Use of this system for study of a novel form of combined 17 alpha-hydroxylase/17,20-lyase deficiency.
Imai T; Globerman H; Gertner JM; Kagawa N; Waterman MR
J Biol Chem; 1993 Sep; 268(26):19681-9. PubMed ID: 8396144
[TBL] [Abstract][Full Text] [Related]
6. Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
Beaudoin C; Lavallée B; Tremblay Y; Hum DW; Breton R; de Launoit Y; Bélanger A
DNA Cell Biol; 1998 Aug; 17(8):707-15. PubMed ID: 9726253
[TBL] [Abstract][Full Text] [Related]
7. Molecular cloning and heterologous expression in E. coli of cytochrome P45017alpha. Comparison of structural and functional properties of substrate-specific cytochromes P450 from different species.
Gilep AA; Estabrook RW; Usanov SA
Biochemistry (Mosc); 2003 Jan; 68(1):86-98. PubMed ID: 12693981
[TBL] [Abstract][Full Text] [Related]
8. Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17.
Soucy P; Luu-The V
J Steroid Biochem Mol Biol; 2002 Jan; 80(1):71-5. PubMed ID: 11867265
[TBL] [Abstract][Full Text] [Related]
9. Cytochrome P450c17 from porcine and bovine adrenal catalyses the formation of 5,16-androstadien-3 beta-ol from pregnenolone in the presence of cytochrome b5.
Meadus WJ; Mason JI; Squires EJ
J Steroid Biochem Mol Biol; 1993 Nov; 46(5):565-72. PubMed ID: 8240978
[TBL] [Abstract][Full Text] [Related]
10. Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase.
Soucy P; Lacoste L; Luu-The V
Eur J Biochem; 2003 Mar; 270(6):1349-55. PubMed ID: 12631293
[TBL] [Abstract][Full Text] [Related]
11. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
Lin D; Black SM; Nagahama Y; Miller WL
Endocrinology; 1993 Jun; 132(6):2498-506. PubMed ID: 8504753
[TBL] [Abstract][Full Text] [Related]
12. Genetically engineered P450 monooxygenases: construction of bovine P450c17/yeast reductase fused enzymes.
Shibata M; Sakaki T; Yabusaki Y; Murakami H; Ohkawa H
DNA Cell Biol; 1990; 9(1):27-36. PubMed ID: 2180429
[TBL] [Abstract][Full Text] [Related]
13. Chimerogenesis in estimation of specificity and pathway directions for cytochrome p45017alpha catalyzed reactions.
Gilep AA; Estabrook RW; Usanov SA
Biochemistry (Mosc); 2004 Apr; 69(4):364-75. PubMed ID: 15170370
[TBL] [Abstract][Full Text] [Related]
14. High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein.
Fisher CW; Shet MS; Caudle DL; Martin-Wixtrom CA; Estabrook RW
Proc Natl Acad Sci U S A; 1992 Nov; 89(22):10817-21. PubMed ID: 1438282
[TBL] [Abstract][Full Text] [Related]
15. Molecular cloning and expression of guinea pig cytochrome P450c17 cDNA (steroid 17 alpha-hydroxylase/17,20 lyase): tissue distribution, regulation, and substrate specificity of the expressed enzyme.
Tremblay Y; Fleury A; Beaudoin C; Vallée M; Bélanger A
DNA Cell Biol; 1994 Dec; 13(12):1199-212. PubMed ID: 7811386
[TBL] [Abstract][Full Text] [Related]
16. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.
Brock BJ; Waterman MR
Biochemistry; 1999 Feb; 38(5):1598-606. PubMed ID: 9931027
[TBL] [Abstract][Full Text] [Related]
17. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
Soucy P; Luu-The V
Eur J Biochem; 2000 Jun; 267(11):3243-7. PubMed ID: 10824109
[TBL] [Abstract][Full Text] [Related]
18. Molecular modeling of human P450c17 (17alpha-hydroxylase/17,20-lyase): insights into reaction mechanisms and effects of mutations.
Auchus RJ; Miller WL
Mol Endocrinol; 1999 Jul; 13(7):1169-82. PubMed ID: 10406467
[TBL] [Abstract][Full Text] [Related]
19. Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.
Gonzalez E; Guengerich FP
J Biol Chem; 2017 Aug; 292(32):13168-13185. PubMed ID: 28684414
[TBL] [Abstract][Full Text] [Related]
20. The use of electrochemistry for the synthesis of 17 alpha-hydroxyprogesterone by a fusion protein containing P450c17.
Estabrook RW; Shet MS; Faulkner K; Fisher CW
Endocr Res; 1996 Nov; 22(4):665-71. PubMed ID: 8969926
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]