These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 1782010)

  • 41. Interaction of 1,N6-ethenoadenine derivatives of triphosphopyridine and reduced triphosphopyridine nucleotides with dihydrofolate reductase from amethopterin-resistant L1210 cells.
    Neef VG; Huennekens FM
    Biochemistry; 1976 Sep; 15(18):4042-7. PubMed ID: 9129
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Expression of variant dihydrofolate reductase with decreased binding affinity to antifolates in MOLT-3 human leukemia cell lines resistant to trimetrexate.
    Miyachi H; Takemura Y; Kobayashi H; Ando Y
    Cancer Lett; 1995 Jan; 88(1):93-9. PubMed ID: 7850779
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Ion-dependent activation of dihydrofolate reductase from L1210 cells.
    Reyes P; Huennekens FM
    Biochemistry; 1967 Nov; 6(11):3519-27. PubMed ID: 5235146
    [No Abstract]   [Full Text] [Related]  

  • 44. Methotrexate analogues. 34. Replacement of the glutamate moiety in methotrexate and aminopterin by long-chain 2-aminoalkanedioic acids.
    Rosowsky A; Bader H; Kohler W; Freisheim JH; Moran RG
    J Med Chem; 1988 Jul; 31(7):1338-44. PubMed ID: 2898531
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Dihydrofolate reductase activity of leukemia L1210 during development of methotrexate resistance.
    Schrecker AW; Mead JA; Greenberg NH; Goldin A
    Biochem Pharmacol; 1971 Mar; 20(3):716-8. PubMed ID: 5150168
    [No Abstract]   [Full Text] [Related]  

  • 46. A direct ligand-binding radioassay for the measurement of methotrexate in tissues and biological fluids.
    Arons E; Rothenberg SP; Costa MD; Fischer C; Iqbal MP
    Cancer Res; 1975 Aug; 35(8):2033-8. PubMed ID: 807320
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Methotrexate metabolism in mutant Chinese hamster ovary cells lacking dihydrofolate reductase.
    Joannon P; Whitehead VM; Rosenblatt DS; Vuchich MJ; Beaulieu D
    Biochem Pharmacol; 1987 Apr; 36(7):1091-7. PubMed ID: 2436625
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Reversibility of high-affinity binding of methotrexate in L1210 murine leukemia cells.
    Cohen M; Bender RA; Donehower R; Myers CE; Chabner BA
    Cancer Res; 1978 Sep; 38(9):2866-70. PubMed ID: 679194
    [No Abstract]   [Full Text] [Related]  

  • 49. Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells.
    Sierra EE; Brigle KE; Spinella MJ; Goldman ID
    Biochem Pharmacol; 1995 Oct; 50(8):1287-94. PubMed ID: 7488246
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Utilization of an immunostaining technique to demonstrate heterogeneity in the content of dihydrofolate reductase in peripheral blast cells from a patient with acute lymphocytic leukemia.
    Grill SP; Wells RJ; Cheng YC
    Cancer Res; 1984 Mar; 44(3):1252-6. PubMed ID: 6581868
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Evaluation of the importance of hydrophobic interactions in drug binding to dihydrofolate reductase.
    Taira K; Benkovic SJ
    J Med Chem; 1988 Jan; 31(1):129-37. PubMed ID: 3275776
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Bovine liver dihydrofolate reductase: purification and properties of the enzyme.
    Peterson DL; Gleisner JM; Blakley RL
    Biochemistry; 1975 Dec; 14(24):5261-7. PubMed ID: 45
    [TBL] [Abstract][Full Text] [Related]  

  • 53. "Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.
    Bertino JR; Cashmore AR; Hillcoat BL
    Cancer Res; 1970 Sep; 30(9):2372-8. PubMed ID: 4394460
    [No Abstract]   [Full Text] [Related]  

  • 54. Improved purification of tetrahydrofolate dehydrogenase from L1210 leukemia by affinity chromatography.
    Chello PL; Cashmore AR; Jacobs SA; Bertino JR
    Biochim Biophys Acta; 1972 Apr; 268(1):30-4. PubMed ID: 5018279
    [No Abstract]   [Full Text] [Related]  

  • 55. The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.
    Cao H; Gao M; Zhou H; Skolnick J
    Commun Biol; 2018; 1():226. PubMed ID: 30564747
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH.
    Cody V; Luft JR; Pangborn W
    Acta Crystallogr D Biol Crystallogr; 2005 Feb; 61(Pt 2):147-55. PubMed ID: 15681865
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Kinetic investigation of the reaction mechanism of dihydrofolate reductase from L1210 cells.
    McCullough JL; Nixon PF; Bertino JR
    Ann N Y Acad Sci; 1971 Nov; 186():131-42. PubMed ID: 4399849
    [No Abstract]   [Full Text] [Related]  

  • 58. Some biochemical characteristics of L1210 cell lines resistant to 6-mercaptopurine and 6-thioguanine and with increased sensitivity to methotrexate.
    Strobel-Stevens JD; El Dareer SM; Trader MW; Hill DL
    Biochem Pharmacol; 1982 Oct; 31(19):3133-7. PubMed ID: 6890814
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Kinetics of substrate, coenzyme, and inhibitor binding to Escherichia coli dihydrofolate reductase.
    Cayley PJ; Dunn SM; King RW
    Biochemistry; 1981 Feb; 20(4):874-9. PubMed ID: 7011378
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification by affinity chromatography and ultraviolet difference spectrophotometric and circular dichroic studies.
    Gupta SV; Greenfield NJ; Poe M; Makulu DR; Williams MN; Moroson BA; Bertino JR
    Biochemistry; 1977 Jul; 16(14):3073-9. PubMed ID: 19040
    [No Abstract]   [Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.