BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 17827000)

  • 1. (1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.
    Hu LY; Du D; Hoffman J; Smith Y; Fedij V; Kostlan C; Johnson TR; Huang Y; Kesten S; Harter W; Yue WS; Li JJ; Barvian N; Mitchell L; Lei HJ; Lefker B; Carroll M; Dettling D; Krieger-Burke T; Samas B; Yalamanchili R; Lapham K; Pocalyko D; Sliskovic D; Ciotti S; Stoller B; Hena MA; Ding Q; Maiti SN; Stier M; Welgus H
    Bioorg Med Chem Lett; 2007 Nov; 17(21):5983-8. PubMed ID: 17827000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production.
    Hu LY; Lei HJ; Du D; Johnson TR; Fedij V; Kostlan C; Yue WS; Lovdahl M; Li JJ; Carroll M; Dettling D; Asbill J; Fan C; Wade K; Pocalyko D; Lapham K; Yalamanchili R; Samas B; Vrieze D; Ciotti S; Krieger-Burke T; Sliskovic D; Welgus H
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5693-7. PubMed ID: 17766112
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production.
    Mitchell L; Wang Z; Hu LY; Kostlan C; Carroll M; Dettling D; Du D; Pocalyko D; Wade K
    Bioorg Med Chem Lett; 2009 Mar; 19(5):1310-3. PubMed ID: 19201190
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rational design of a topical androgen receptor antagonist for the suppression of sebum production with properties suitable for follicular delivery.
    Mitchell LH; Johnson TR; Lu GW; Du D; Datta K; Grzemski F; Shanmugasundaram V; Spence J; Wade K; Wang Z; Sun K; Lin K; Hu LY; Sexton K; Raheja N; Kostlan C; Pocalyko D
    J Med Chem; 2010 Jun; 53(11):4422-7. PubMed ID: 20462217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications.
    Li JJ; Iula DM; Nguyen MN; Hu LY; Dettling D; Johnson TR; Du DY; Shanmugasundaram V; Van Camp JA; Wang Z; Harter WG; Yue WS; Boys ML; Wade KJ; Drummond EM; Samas BM; Lefker BA; Hoge GS; Lovdahl MJ; Asbill J; Carroll M; Meade MA; Ciotti SM; Krieger-Burke T
    J Med Chem; 2008 Nov; 51(21):7010-4. PubMed ID: 18921992
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production.
    Mitchell LH; Hu LY; Nguyen M; Fakhoury S; Smith Y; Iula D; Kostlan C; Carroll M; Dettling D; Du D; Pocalyko D; Wade K; Lefker B
    Bioorg Med Chem Lett; 2009 Apr; 19(8):2176-8. PubMed ID: 19286380
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production.
    Van Camp JA; Hu LY; Kostlan C; Lefker B; Li J; Mitchell L; Wang Z; Yue WS; Carroll M; Dettling D; Du D; Pocalyko D; Wade K
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5529-32. PubMed ID: 17764935
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice.
    De Brouwer B; Tételin C; Leroy T; Bonfils A; Van Neste D
    Br J Dermatol; 1997 Nov; 137(5):699-702. PubMed ID: 9415227
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of sex steroid deprivation/administration on hair growth and skin sebum production in transsexual males and females.
    Giltay EJ; Gooren LJ
    J Clin Endocrinol Metab; 2000 Aug; 85(8):2913-21. PubMed ID: 10946903
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pantolactams as androgen receptor antagonists for the topical suppression of sebum production.
    Sexton KE; Barrett S; Bridgwood K; Carroll M; Dettling D; Du D; Fakhoury S; Fedij V; Hu LY; Kostlan C; Pocalyko D; Raheja N; Smith Y; Shanmugasundaram V; Wade K
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5230-3. PubMed ID: 21831636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The hair cycle of the Syrian golden hamster (Mesocricetus auratus).
    Musser TK; Silverman J
    Lab Anim Sci; 1980 Aug; 30(4 Pt 1):681-3. PubMed ID: 7421115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Local inhibition of sebaceous gland growth by topically applied RU 58841.
    Matias JR; Gaillard M
    Ann N Y Acad Sci; 1995 Jun; 761():56-65. PubMed ID: 7625751
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deposition of salicylic acid into hamster sebaceous.
    Motwani MR; Rhein LD; Zatz JL
    J Cosmet Sci; 2004; 55(6):519-31. PubMed ID: 15645108
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of artificial sebum with human and hamster sebum samples.
    Lu GW; Valiveti S; Spence J; Zhuang C; Robosky L; Wade K; Love A; Hu LY; Pole D; Mollan M
    Int J Pharm; 2009 Feb; 367(1-2):37-43. PubMed ID: 18929636
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives.
    Asano M; Hitaka T; Imada T; Yamada M; Morimoto M; Shinohara H; Hara T; Yamaoka M; Santou T; Nakayama M; Imai Y; Habuka N; Yano J; Wilson K; Fujita H; Hasuoka A
    Bioorg Med Chem Lett; 2017 May; 27(9):1897-1901. PubMed ID: 28363748
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring.
    Ohta K; Goto T; Fijii S; Suzuki T; Ohta S; Endo Y
    Bioorg Med Chem; 2008 Sep; 16(17):8022-8. PubMed ID: 18707892
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of the antiandrogen II alpha-hydroxyprogesterone on sebum production and cholesterol concentration of sebum.
    Tamm J; Seckelmann M; Volkwein U; Ludwig E
    Br J Dermatol; 1982 Jul; 107(1):63-70. PubMed ID: 6213252
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of ear sebum of the Syrian hamster (Mesocricetus auratus) reveals pronounced sexual dimorphism.
    Brind JL; Alani E; Wheatley VR; Orentreich N
    Comp Biochem Physiol B; 1986; 84(3):403-7. PubMed ID: 3743033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dihydrotestosterone inhibits murine hair growth via the androgen receptor.
    Naito A; Sato T; Matsumoto T; Takeyama K; Yoshino T; Kato S; Ohdera M
    Br J Dermatol; 2008 Aug; 159(2):300-5. PubMed ID: 18547308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of sodium R-(+)-4-{2-[5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (elagolix), a potent and orally available nonpeptide antagonist of the human gonadotropin-releasing hormone receptor.
    Chen C; Wu D; Guo Z; Xie Q; Reinhart GJ; Madan A; Wen J; Chen T; Huang CQ; Chen M; Chen Y; Tucci FC; Rowbottom M; Pontillo J; Zhu YF; Wade W; Saunders J; Bozigian H; Struthers RS
    J Med Chem; 2008 Dec; 51(23):7478-85. PubMed ID: 19006286
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.