89 related articles for article (PubMed ID: 17827015)
21. Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors.
Li Q; Woods KW; Wang W; Lin NH; Claiborne A; Gu WZ; Cohen J; Stoll VS; Hutchins C; Frost D; Rosenberg SH; Sham HL
Bioorg Med Chem Lett; 2005 Apr; 15(8):2033-9. PubMed ID: 15808463
[TBL] [Abstract][Full Text] [Related]
22. Structural feature study of benzofuran derivatives as farnesyltransferase inhibitors.
Moorthy NS; Sousa SF; Ramos MJ; Fernandes PA
J Enzyme Inhib Med Chem; 2011 Dec; 26(6):777-91. PubMed ID: 21381884
[TBL] [Abstract][Full Text] [Related]
23. New farnesyltransferase inhibitors in the phenothiazine series.
Belei D; Dumea C; Samson A; Farce A; Dubois J; Bîcu E; Ghinet A
Bioorg Med Chem Lett; 2012 Jul; 22(14):4517-22. PubMed ID: 22738631
[TBL] [Abstract][Full Text] [Related]
24. Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase.
Dumea C; Belei D; Ghinet A; Dubois J; Farce A; Bîcu E
Bioorg Med Chem Lett; 2014 Dec; 24(24):5777-5781. PubMed ID: 25453818
[TBL] [Abstract][Full Text] [Related]
25. Computer-aided drug design and ADMET predictions for identification and evaluation of novel potential farnesyltransferase inhibitors in cancer therapy.
da Silva CH; da Silva VB; Resende J; Rodrigues PF; Bononi FC; Benevenuto CG; Taft CA
J Mol Graph Model; 2010 Feb; 28(6):513-23. PubMed ID: 20074987
[TBL] [Abstract][Full Text] [Related]
26. Phenothiazine-based CaaX competitive inhibitors of human farnesyltransferase bearing a cysteine, methionine, serine or valine moiety as a new family of antitumoral compounds.
Dumitriu GM; Bîcu E; Belei D; Rigo B; Dubois J; Farce A; Ghinet A
Bioorg Med Chem Lett; 2015 Oct; 25(20):4447-52. PubMed ID: 26372651
[TBL] [Abstract][Full Text] [Related]
27. 7-imidazolylalkanamido-1-carboxylalkylbenzo-diazepine, a novel series of farnesyltransferase inhibitors.
Wan SB; Chu FM; Guo ZR
Yao Xue Xue Bao; 2002 Jul; 37(7):516-21. PubMed ID: 12914320
[TBL] [Abstract][Full Text] [Related]
28. In vitro and in vivo evaluation of two rational-designed nonpeptidic farnesyltransferase inhibitors on HT29 human colon cancer cell lines.
Wlodarczyk N; Gilleron P; Millet R; Houssin R; Goossens JF; Lemoine A; Pommery N; Wei MX; Hénichart JP
Oncol Res; 2005; 16(3):107-18. PubMed ID: 16925112
[TBL] [Abstract][Full Text] [Related]
29. Design and synthesis of o-trifluoromethylbiphenyl substituted 2-amino-nicotinonitriles as inhibitors of farnesyltransferase.
Wang GT; Wang X; Wang W; Hasvold LA; Sullivan G; Hutchins CW; O'Conner S; Gentiles R; Sowin T; Cohen J; Gu WZ; Zhang H; Rosenberg SH; Sham HL
Bioorg Med Chem Lett; 2005 Jan; 15(1):153-8. PubMed ID: 15582430
[TBL] [Abstract][Full Text] [Related]
30. Impact on farnesyltransferase inhibition of 4-chlorophenyl moiety replacement in the Zarnestra series.
Angibaud P; Mevellec L; Meyer C; Bourdrez X; Lezouret P; Pilatte I; Poncelet V; Roux B; Merillon S; End DW; Van Dun J; Wouters W; Venet M
Eur J Med Chem; 2007 May; 42(5):702-14. PubMed ID: 17316920
[TBL] [Abstract][Full Text] [Related]
31. Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors.
Cadelis MM; Bourguet-Kondracki ML; Dubois J; Valentin A; Barker D; Copp BR
Bioorg Med Chem; 2016 Jul; 24(14):3102-7. PubMed ID: 27240468
[TBL] [Abstract][Full Text] [Related]
32. Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.
Rokosz LL; Huang CY; Reader JC; Stauffer TM; Chelsky D; Sigal NH; Ganguly AK; Baldwin JJ
Bioorg Med Chem Lett; 2005 Dec; 15(24):5537-43. PubMed ID: 16202593
[TBL] [Abstract][Full Text] [Related]
33. Novel triazole based inhibitors of Ras farnesyl transferase.
Saha AK; Liu L; Simoneaux R; DeCorte B; Meyer C; Skrzat S; Breslin HJ; Kukla MJ; End DW
Bioorg Med Chem Lett; 2005 Dec; 15(24):5407-11. PubMed ID: 16216509
[TBL] [Abstract][Full Text] [Related]
34. Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency.
Bolchi C; Pallavicini M; Rusconi C; Diomede L; Ferri N; Corsini A; Fumagalli L; Pedretti A; Vistoli G; Valoti E
Bioorg Med Chem Lett; 2007 Nov; 17(22):6192-6. PubMed ID: 17889533
[TBL] [Abstract][Full Text] [Related]
35. Structure-based design of lipophilic quinazoline inhibitors of thymidylate synthase.
Jones TR; Varney MD; Webber SE; Lewis KK; Marzoni GP; Palmer CL; Kathardekar V; Welsh KM; Webber S; Matthews DA; Appelt K; Smith WW; Janson CA; Villafranca JE; Bacquet RJ; Howland EF; Booth CL; Herrmann SM; Ward RW; White J; Moomaw EW; Bartlett CA; Morse CA
J Med Chem; 1996 Feb; 39(4):904-17. PubMed ID: 8632414
[TBL] [Abstract][Full Text] [Related]
36. 3D-QSAR with the aid of pharmacophore search and docking-based alignments for farnesyltransferase inhibitors.
Vaidya M; Weigt M; Wiese M
Eur J Med Chem; 2009 Oct; 44(10):4070-82. PubMed ID: 19515462
[TBL] [Abstract][Full Text] [Related]
37. QSAR study on tetrahydroquinoline analogues as plasmodium protein farnesyltransferase inhibitors: a comparison of rationales of malarial and mammalian enzyme inhibitory activities for selectivity.
Gupta MK; Prabhakar YS
Eur J Med Chem; 2008 Dec; 43(12):2751-67. PubMed ID: 18329140
[TBL] [Abstract][Full Text] [Related]
38. Exploring structure-activity relationships of tricyclic farnesyltransferase inhibitors using ECLiPS libraries.
Rokosz LL; Huang CY; Reader JC; Stauffer TM; Southwick EC; Li G; Chelsky D; Baldwin JJ
Comb Chem High Throughput Screen; 2006 Aug; 9(7):545-58. PubMed ID: 16925514
[TBL] [Abstract][Full Text] [Related]
39. New asymmetric synthesis of protein farnesyltransferase inhibitors via palladium-catalyzed cross-coupling reactions of 2-iodo-imidazoles.
Kerhervé J; Botuha C; Dubois J
Org Biomol Chem; 2009 May; 7(10):2214-22. PubMed ID: 19421463
[TBL] [Abstract][Full Text] [Related]
40. Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents.
Fletcher S; Keaney EP; Cummings CG; Blaskovich MA; Hast MA; Glenn MP; Chang SY; Bucher CJ; Floyd RJ; Katt WP; Gelb MH; Van Voorhis WC; Beese LS; Sebti SM; Hamilton AD
J Med Chem; 2010 Oct; 53(19):6867-88. PubMed ID: 20822181
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]