These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 17827752)

  • 61. Antitumor agents. Part 186: Synthesis and biological evaluation of demethylcolchiceinamide analogues as cytotoxic DNA topoisomerase II inhibitors.
    Guan J; Zhu XK; Tachibana Y; Bastow KF; Brossi A; Hamel E; Lee KH
    Bioorg Med Chem; 1998 Nov; 6(11):2127-31. PubMed ID: 9881102
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives.
    Bouchikhi F; Anizon F; Moreau P
    Eur J Med Chem; 2008 Apr; 43(4):755-62. PubMed ID: 17628214
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Aryl-indolyl maleimides as inhibitors of CaMKIIdelta. Part 2: SAR of the amine tether.
    Levy DE; Wang DX; Lu Q; Chen Z; Perumattam J; Xu YJ; Higaki J; Dong H; Liclican A; Laney M; Mavunkel B; Dugar S
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2395-8. PubMed ID: 18334295
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Synthesis and biological evaluation of 1-(4'-Indolyl and 6'-Quinolinyl) indoles as a new class of potent anticancer agents.
    Lai MJ; Chang JY; Lee HY; Kuo CC; Lin MH; Hsieh HP; Chang CY; Wu JS; Wu SY; Shey KS; Liou JP
    Eur J Med Chem; 2011 Sep; 46(9):3623-9. PubMed ID: 21641700
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S; Vandenberghe I; Robin M; Annereau JP; Créancier L; Pique V; Galy JP; Kruczynski A; Barret JM; Bailly C
    Biochem Pharmacol; 2007 Jun; 73(12):1863-72. PubMed ID: 17391647
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Design, synthesis, structure-activity relationships study and X-ray crystallography of 3-substituted-indolin-2-one-5-carboxamide derivatives as PAK4 inhibitors.
    Guo J; Zhao F; Yin W; Zhu M; Hao C; Pang Y; Wu T; Wang J; Zhao D; Li H; Cheng M
    Eur J Med Chem; 2018 Jul; 155():197-209. PubMed ID: 29886323
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Synthesis, topoisomerase I inhibitory activity and in vitro cytotoxicity of camptothecin derivatives bearing five-membered heterocycle containing 10-substituents.
    Zhao R; Guan LL; Oreski B; Lown JW
    Anticancer Drug Des; 1998 Mar; 13(2):145-57. PubMed ID: 9524556
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Protecting group-free radical decarboxylation of bile acids: Synthesis of novel steroidal substituted maleic anhydrides and maleimides and evaluation of their cytotoxicity on C6 rat glioma cells.
    Samadi M; Nury T; Khalafi-Nezhad A; Lizard G
    Steroids; 2017 Sep; 125():124-130. PubMed ID: 28711707
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors.
    Zhu G; Conner SE; Zhou X; Shih C; Li T; Anderson BD; Brooks HB; Campbell RM; Considine E; Dempsey JA; Faul MM; Ogg C; Patel B; Schultz RM; Spencer CD; Teicher B; Watkins SA
    J Med Chem; 2003 May; 46(11):2027-30. PubMed ID: 12747775
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison.
    Karki R; Park C; Jun KY; Kadayat TM; Lee ES; Kwon Y
    Eur J Med Chem; 2015 Jan; 90():360-78. PubMed ID: 25437622
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity.
    Schultz C; Link A; Leost M; Zaharevitz DW; Gussio R; Sausville EA; Meijer L; Kunick C
    J Med Chem; 1999 Jul; 42(15):2909-19. PubMed ID: 10425100
    [TBL] [Abstract][Full Text] [Related]  

  • 72. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
    Karki R; Jun KY; Kadayat TM; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Eur J Med Chem; 2016 May; 113():228-45. PubMed ID: 26945111
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11.
    Saulnier MG; Balasubramanian BN; Long BH; Frennesson DB; Ruediger E; Zimmermann K; Eummer JT; St Laurent DR; Stoffan KM; Naidu BN; Mahler M; Beaulieu F; Bachand C; Lee FY; Fairchild CR; Stadnick LK; Rose WC; Solomon C; Wong H; Martel A; Wright JJ; Kramer R; Langley DR; Vyas DM
    J Med Chem; 2005 Apr; 48(7):2258-61. PubMed ID: 15801816
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Synthesis and in vitro cytotoxic evaluation of N-substituted benzo[5,6]cycloheptal[b]indoles.
    Joseph B; Alagille D; Mérour JY; Léonce S
    Chem Pharm Bull (Tokyo); 2000 Dec; 48(12):1872-6. PubMed ID: 11145134
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds.
    Guillaumel J; Léonce S; Pierré A; Renard P; Pfeiffer B; Arimondo PB; Monneret C
    Eur J Med Chem; 2006 Mar; 41(3):379-86. PubMed ID: 16442188
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE; Gedawy EM
    Eur J Med Chem; 2018 Apr; 150():403-418. PubMed ID: 29547830
    [TBL] [Abstract][Full Text] [Related]  

  • 77. 3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation.
    Hu Y; Gao A; Liao H; Zhang M; Xu G; Gao L; Xu L; Zhou Y; Gao J; Ye Q; Li J
    Arch Pharm (Weinheim); 2018 Oct; 351(10):e1800039. PubMed ID: 30113716
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Design and synthesis of (aza)indolyl maleimide-based covalent inhibitors of glycogen synthase kinase 3β.
    Yang Z; Liu H; Pan B; He F; Pan Z
    Org Biomol Chem; 2018 Jun; 16(22):4127-4140. PubMed ID: 29781013
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Synthesis and inhibitory activity of novel tri- and tetracyclic quinolines against topoisomerases.
    Sui Z; Altom J; Nguyen VN; Fernandez J; Bernstein JI; Hiliard JJ; Barrett JF; Podlogar BL; Ohemeng KA
    Bioorg Med Chem; 1998 Jun; 6(6):735-42. PubMed ID: 9681139
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Cytotoxicity and topoisomerase I/II inhibition of glycosylated 2-phenyl-indoles, 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans.
    Shi W; Marcus SL; Lowary TL
    Bioorg Med Chem; 2011 Jan; 19(1):603-12. PubMed ID: 21094049
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.