BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 17844994)

  • 1. Benzochromenones from the marine crinoid Comantheria rotula inhibit hypoxia-inducible factor-1 (HIF-1) in cell-based reporter assays and differentially suppress the growth of certain tumor cell lines.
    Dai J; Liu Y; Jia H; Zhou YD; Nagle DG
    J Nat Prod; 2007 Sep; 70(9):1462-6. PubMed ID: 17844994
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sodwanone and yardenone triterpenes from a South African species of the marine sponge Axinella inhibit hypoxia-inducible factor-1 (HIF-1) activation in both breast and prostate tumor cells.
    Dai J; Fishback JA; Zhou YD; Nagle DG
    J Nat Prod; 2006 Dec; 69(12):1715-20. PubMed ID: 17190448
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular-targeted antitumor agents. 15. Neolamellarins from the marine sponge Dendrilla nigra inhibit hypoxia-inducible factor-1 activation and secreted vascular endothelial growth factor production in breast tumor cells.
    Liu R; Liu Y; Zhou YD; Nagle DG
    J Nat Prod; 2007 Nov; 70(11):1741-5. PubMed ID: 17958397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Laurenditerpenol, a new diterpene from the tropical marine alga Laurenciaintricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells.
    Mohammed KA; Hossain CF; Zhang L; Bruick RK; Zhou YD; Nagle DG
    J Nat Prod; 2004 Dec; 67(12):2002-7. PubMed ID: 15620241
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells.
    Du L; Mahdi F; Datta S; Jekabsons MB; Zhou YD; Nagle DG
    J Nat Prod; 2012 Sep; 75(9):1553-9. PubMed ID: 22938093
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia-selective antitumor agents: norsesterterpene peroxides from the marine sponge Diacarnus levii preferentially suppress the growth of tumor cells under hypoxic conditions.
    Dai J; Liu Y; Zhou YD; Nagle DG
    J Nat Prod; 2007 Jan; 70(1):130-3. PubMed ID: 17253866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytotoxic metabolites from an Indonesian sponge Lendenfeldia sp.
    Dai J; Liu Y; Zhou YD; Nagle DG
    J Nat Prod; 2007 Nov; 70(11):1824-6. PubMed ID: 17958396
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structures and potential antitumor activity of sesterterpenes from the marine sponge Hyrtios communis.
    Li J; Du L; Kelly M; Zhou YD; Nagle DG
    J Nat Prod; 2013 Aug; 76(8):1492-7. PubMed ID: 23944963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strongylophorines: natural product inhibitors of hypoxia-inducible factor-1 transcriptional pathway.
    Mohammed KA; Jadulco RC; Bugni TS; Harper MK; Sturdy M; Ireland CM
    J Med Chem; 2008 Mar; 51(5):1402-5. PubMed ID: 18278856
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular-targeted antitumor agents. 19. Furospongolide from a marine Lendenfeldia sp. sponge inhibits hypoxia-inducible factor-1 activation in breast tumor cells.
    Liu Y; Liu R; Mao SC; Morgan JB; Jekabsons MB; Zhou YD; Nagle DG
    J Nat Prod; 2008 Nov; 71(11):1854-60. PubMed ID: 18989978
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1.
    Hodges TW; Hossain CF; Kim YP; Zhou YD; Nagle DG
    J Nat Prod; 2004 May; 67(5):767-71. PubMed ID: 15165135
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
    Chau NM; Rogers P; Aherne W; Carroll V; Collins I; McDonald E; Workman P; Ashcroft M
    Cancer Res; 2005 Jun; 65(11):4918-28. PubMed ID: 15930314
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration.
    Du L; Mahdi F; Jekabsons MB; Nagle DG; Zhou YD
    J Nat Prod; 2011 Feb; 74(2):240-8. PubMed ID: 21214226
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
    Rapisarda A; Uranchimeg B; Scudiero DA; Selby M; Sausville EA; Shoemaker RH; Melillo G
    Cancer Res; 2002 Aug; 62(15):4316-24. PubMed ID: 12154035
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos.
    Li J; Mahdi F; Du L; Jekabsons MB; Zhou YD; Nagle DG
    Bioorg Med Chem; 2013 Apr; 21(7):1795-803. PubMed ID: 23434131
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lipophilic 2,5-disubstituted pyrroles from the marine sponge Mycale sp. inhibit mitochondrial respiration and HIF-1 activation.
    Mao SC; Liu Y; Morgan JB; Jekabsons MB; Zhou YD; Nagle DG
    J Nat Prod; 2009 Nov; 72(11):1927-36. PubMed ID: 19845338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of 3-(phenylethynyl)-1,1'-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors.
    Wang S; Wang X; Shao Y; Shao K; Wang Y; Guo X; Dong H; Zhao W; Li Y; Li G
    Bioorg Chem; 2021 Nov; 116():105298. PubMed ID: 34454298
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low Molecular Weight Fucoidan Inhibits Tumor Angiogenesis through Downregulation of HIF-1/VEGF Signaling under Hypoxia.
    Chen MC; Hsu WL; Hwang PA; Chou TC
    Mar Drugs; 2015 Jul; 13(7):4436-51. PubMed ID: 26193287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships study of neolamellarin A and its analogues as hypoxia inducible factor-1 (HIF-1) inhibitors.
    Li G; Dong H; Ma Y; Shao K; Li Y; Wu X; Wang S; Shao Y; Zhao W
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2327-2331. PubMed ID: 31281016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding.
    Jones DT; Harris AL
    Mol Cancer Ther; 2006 Sep; 5(9):2193-202. PubMed ID: 16985052
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.