BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 17846171)

  • 1. A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop.
    Xiong L; Kou F; Yang Y; Wu J
    J Cell Biol; 2007 Sep; 178(6):995-1007. PubMed ID: 17846171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.
    Worrall C; Suleymanova N; Crudden C; Trocoli Drakensjö I; Candrea E; Nedelcu D; Takahashi SI; Girnita L; Girnita A
    Oncogene; 2017 Jun; 36(23):3274-3286. PubMed ID: 28092675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor.
    Girnita L; Girnita A; Larsson O
    Proc Natl Acad Sci U S A; 2003 Jul; 100(14):8247-52. PubMed ID: 12821780
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rapamycin increases the p53/MDM2 protein ratio and p53-dependent apoptosis by translational inhibition of mdm2 in cancer cells.
    Kao CL; Hsu HS; Chen HW; Cheng TH
    Cancer Lett; 2009 Dec; 286(2):250-9. PubMed ID: 19560264
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop.
    Arriola EL; Lopez AR; Chresta CM
    Oncogene; 1999 Jan; 18(4):1081-91. PubMed ID: 10023685
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor.
    Davaadelger B; Duan L; Perez RE; Gitelis S; Maki CG
    Oncotarget; 2016 May; 7(19):27511-26. PubMed ID: 27050276
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IGF-1R/MDM2 relationship confers enhanced sensitivity to RITA in Ewing sarcoma cells.
    Di Conza G; Buttarelli M; Monti O; Pellegrino M; Mancini F; Pontecorvi A; Scotlandi K; Moretti F
    Mol Cancer Ther; 2012 Jun; 11(6):1247-56. PubMed ID: 22461661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The identification of an internal ribosomal entry site in the 5'-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage.
    Yang DQ; Halaby MJ; Zhang Y
    Oncogene; 2006 Aug; 25(33):4613-9. PubMed ID: 16607284
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IGF-1 inhibits the mitochondrial apoptosis program in mesangial cells exposed to high glucose.
    Kang BP; Urbonas A; Baddoo A; Baskin S; Malhotra A; Meggs LG
    Am J Physiol Renal Physiol; 2003 Nov; 285(5):F1013-24. PubMed ID: 12876069
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival.
    Froment P; Dupont J; Christophe-Marine J
    Cell Cycle; 2008 Oct; 7(19):3098-103. PubMed ID: 18802403
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis.
    Leri A; Liu Y; Claudio PP; Kajstura J; Wang X; Wang S; Kang P; Malhotra A; Anversa P
    Am J Pathol; 1999 Feb; 154(2):567-80. PubMed ID: 10027414
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma.
    Friedrichs N; Küchler J; Endl E; Koch A; Czerwitzki J; Wurst P; Metzger D; Schulte JH; Holst MI; Heukamp LC; Larsson O; Tanaka S; Kawai A; Wardelmann E; Buettner R; Pietsch T; Hartmann W
    J Pathol; 2008 Dec; 216(4):428-39. PubMed ID: 18855347
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transformation by human papillomavirus 16 E6 and E7: role of the insulin-like growth factor 1 receptor.
    Steller MA; Zou Z; Schiller JT; Baserga R
    Cancer Res; 1996 Nov; 56(21):5087-91. PubMed ID: 8895768
    [TBL] [Abstract][Full Text] [Related]  

  • 14. OVA66 increases cell growth, invasion and survival via regulation of IGF-1R-MAPK signaling in human cancer cells.
    Rao W; Li H; Song F; Zhang R; Yin Q; Wang Y; Xi Y; Ge H
    Carcinogenesis; 2014 Jul; 35(7):1573-81. PubMed ID: 24667688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The loss of mdm2 induces p53-mediated apoptosis.
    de Rozieres S; Maya R; Oren M; Lozano G
    Oncogene; 2000 Mar; 19(13):1691-7. PubMed ID: 10763826
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells.
    Duan W; Gao L; Wu X; Zhang Y; Otterson GA; Villalona-Calero MA
    Exp Cell Res; 2006 Oct; 312(17):3370-8. PubMed ID: 16934800
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and beta-arrestin1.
    Vasilcanu R; Vasilcanu D; Rosengren L; Natalishvili N; Sehat B; Yin S; Girnita A; Axelson M; Girnita L; Larsson O
    Oncogene; 2008 Mar; 27(11):1629-38. PubMed ID: 17828296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tyrphostin AG 1024 modulates radiosensitivity in human breast cancer cells.
    Wen B; Deutsch E; Marangoni E; Frascona V; Maggiorella L; Abdulkarim B; Chavaudra N; Bourhis J
    Br J Cancer; 2001 Dec; 85(12):2017-21. PubMed ID: 11747348
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2.
    Nair PN; De Armond DT; Adamo ML; Strodel WE; Freeman JW
    Oncogene; 2001 Dec; 20(57):8203-14. PubMed ID: 11781836
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.