These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 17854269)

  • 1. Fine-tuning of ENA gapmers as antisense oligonucleotides for sequence-specific inhibition.
    Takagi-Sato M; Tokuhiro S; Kawaida R; Koizumi M
    Oligonucleotides; 2007; 17(3):291-301. PubMed ID: 17854269
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design of ENA gapmers as fine-tuning antisense oligonucleotides with sequence-specific inhibitory activity on mouse PADI4 mRNA expression.
    Takagi-Sato M; Tokuhiro S; Kawaida R; Koizumi M
    Nucleic Acids Symp Ser (Oxf); 2006; (50):319-20. PubMed ID: 17150946
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of VEGF mRNA by 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) antisense oligonucleotides and their influence on off-target gene expressions.
    Morita K; Yamate K; Kurakata S; Abe K; Watanabe K; Koizumi M; Imanishi T
    Nucleosides Nucleotides Nucleic Acids; 2006; 25(4-6):503-21. PubMed ID: 16838842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antiviral Efficacy of RNase H-Dependent Gapmer Antisense Oligonucleotides against Japanese Encephalitis Virus.
    Okamoto S; Echigoya Y; Tago A; Segawa T; Sato Y; Itou T
    Int J Mol Sci; 2023 Oct; 24(19):. PubMed ID: 37834294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Down-regulation of VEGF mRNA expression by 2'-O,4'-C-ethylene-bridged nucleic acid (ENA) antisense oligonucleotides and investigation of non-target gene expression.
    Morita K; Yamate K; Kurakata S; Abe K; Imanishi T; Koizumi M
    Nucleic Acids Res Suppl; 2002; (2):99-100. PubMed ID: 12903124
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl]-modified oligonucleotides inhibit expression of mRNA in vitro and in vivo.
    Prakash TP; Johnston JF; Graham MJ; Condon TP; Manoharan M
    Nucleic Acids Res; 2004; 32(2):828-33. PubMed ID: 14762210
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice.
    Hagedorn PH; Pontoppidan M; Bisgaard TS; Berrera M; Dieckmann A; Ebeling M; Møller MR; Hudlebusch H; Jensen ML; Hansen HF; Koch T; Lindow M
    Nucleic Acids Res; 2018 Jun; 46(11):5366-5380. PubMed ID: 29790953
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct comparison of in vivo antisense activity of ENA oligonucleotides targeting PTP1B mRNA with that of 2'-O-(2-methoxy)ethyl-modified oligonucleotides.
    Koizumi M; Takagi-Sato M; Okuyama R; Araki K; Sun W; Nakai D; Tsutsumi S; Kawai K
    Oligonucleotides; 2006; 16(3):253-62. PubMed ID: 16978088
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of the RNase H cleavage kinetics and blood serum stability of the north-conformationally constrained and 2'-alkoxy modified oligonucleotides.
    Honcharenko D; Barman J; Varghese OP; Chattopadhyaya J
    Biochemistry; 2007 May; 46(19):5635-46. PubMed ID: 17411072
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ribonuclease H1-dependent hepatotoxicity caused by locked nucleic acid-modified gapmer antisense oligonucleotides.
    Kasuya T; Hori S; Watanabe A; Nakajima M; Gahara Y; Rokushima M; Yanagimoto T; Kugimiya A
    Sci Rep; 2016 Jul; 6():30377. PubMed ID: 27461380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of Computationally Evaluated Target Specificity in the Hepatotoxicity of Gapmer Antisense Oligonucleotides.
    Kasuya T; Kugimiya A
    Nucleic Acid Ther; 2018 Oct; 28(5):312-317. PubMed ID: 30095329
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gapmer Antisense Oligonucleotides Containing 2',3'-Dideoxy-2'-fluoro-3'-C-hydroxymethyl-β-d-lyxofuranosyl Nucleotides Display Site-Specific RNase H Cleavage and Induce Gene Silencing.
    Danielsen MB; Lou C; Lisowiec-Wachnicka J; Pasternak A; Jørgensen PT; Wengel J
    Chemistry; 2020 Jan; 26(6):1368-1379. PubMed ID: 31682037
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4'-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer.
    Fluiter K; Mook OR; Vreijling J; Langkjaer N; Højland T; Wengel J; Baas F
    Mol Biosyst; 2009 Aug; 5(8):838-43. PubMed ID: 19603119
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids.
    Lima WF; Crooke ST
    Biochemistry; 1997 Jan; 36(2):390-8. PubMed ID: 9003192
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antisense phosphorothioate oligonucleotides direct both site-specific and nonspecific RNAse H cleavage of in vitro synthesized p120 mRNA.
    Weidner DA; Busch H
    Oncol Res; 1994; 6(6):237-42. PubMed ID: 7865899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An Investigation into the Potential of Targeting
    Goddard LR; Mardle CE; Gneid H; Ball CG; Gowers DM; Atkins HS; Butt LE; Watts JK; Vincent HA; Callaghan AJ
    Molecules; 2021 Jun; 26(11):. PubMed ID: 34200016
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluating the Knockdown Activity of MALAT1 ENA Gapmers In Vitro.
    Iwashita S; Shoji T; Koizumi M
    Methods Mol Biol; 2020; 2176():155-161. PubMed ID: 32865789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications.
    Mutso M; Nikonov A; Pihlak A; Žusinaite E; Viru L; Selyutina A; Reintamm T; Kelve M; Saarma M; Karelson M; Merits A
    PLoS One; 2015; 10(6):e0128686. PubMed ID: 26039055
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Invention and Early History of Gapmers.
    Lim KRQ; Yokota T
    Methods Mol Biol; 2020; 2176():3-19. PubMed ID: 32865779
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design of antisense oligonucleotides stabilized by locked nucleic acids.
    Kurreck J; Wyszko E; Gillen C; Erdmann VA
    Nucleic Acids Res; 2002 May; 30(9):1911-8. PubMed ID: 11972327
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.