BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 17870537)

  • 1. Synthesis of some tropane derivatives of anticipated activity on the reuptake of norepinephrine and/or serotonin.
    Hanna MM; Eid NM; George RF; Safwat HM
    Bioorg Med Chem; 2007 Dec; 15(24):7765-72. PubMed ID: 17870537
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.
    Zhang A; Zhou G; Hoepping A; Mukhopadhyaya J; Johnson KM; Zhang M; Kozikowski AP
    J Med Chem; 2002 Apr; 45(9):1930-41. PubMed ID: 11960503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.
    Gong PK; Blough BE; Brieaddy LE; Huang X; Kuhar MJ; Navarro HA; Carroll FI
    J Med Chem; 2007 Jul; 50(15):3686-95. PubMed ID: 17602602
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and receptor binding properties of 2beta-alkynyl and 2beta-(1,2,3-triazol)substituted 3beta-(substituted phenyl)tropane derivatives.
    Jin C; Navarro HA; Carroll FI
    Bioorg Med Chem; 2008 May; 16(10):5529-35. PubMed ID: 18434164
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
    Orjales A; Mosquera R; Toledo A; Pumar MC; García N; Cortizo L; Labeaga L; Innerárity A
    J Med Chem; 2003 Dec; 46(25):5512-32. PubMed ID: 14640559
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency.
    Tamagnan G; Alagille D; Fu X; Kula NS; Baldessarini RJ; Innis RB; Baldwin RM
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1131-3. PubMed ID: 15686927
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of 3 beta-aryl-8-azabicyclo[3.2.1]octanes with high binding affinities and selectivities for the serotonin transporter site.
    Davies HM; Kuhn LA; Thornley C; Matasi JJ; Sexton T; Childers SR
    J Med Chem; 1996 Jun; 39(13):2554-8. PubMed ID: 8691453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.
    Hoepping A; Johnson KM; George C; Flippen-Anderson J; Kozikowski AP
    J Med Chem; 2000 May; 43(10):2064-71. PubMed ID: 10821718
    [TBL] [Abstract][Full Text] [Related]  

  • 10. From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies.
    Eildal JN; Andersen J; Kristensen AS; Jørgensen AM; Bang-Andersen B; Jørgensen M; Strømgaard K
    J Med Chem; 2008 May; 51(10):3045-8. PubMed ID: 18429609
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An extended study of dimeric phenyl tropanes.
    Nielsen S; Pedersen CM; Hansen SG; Petersen MD; Sinning S; Wiborg O; Jensen HH; Bols M
    Bioorg Med Chem; 2009 Jul; 17(14):4900-9. PubMed ID: 19560930
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects.
    Chappell JC; Eisenhofer G; Owens MJ; Haber H; Lachno DR; Dean RA; Knadler MP; Nemeroff CB; Mitchell MI; Detke MJ; Iyengar S; Pangallo B; Lobo ED
    J Clin Psychopharmacol; 2014 Feb; 34(1):9-16. PubMed ID: 24346757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. (11) C and (18) F PET radioligands for the serotonin transporter (SERT).
    Stehouwer JS; Goodman MM
    J Labelled Comp Radiopharm; 2013; 56(3-4):114-9. PubMed ID: 24285317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.
    Zhang S; Fernandez F; Hazeldine S; Deschamps J; Zhen J; Reith ME; Dutta AK
    J Med Chem; 2006 Jul; 49(14):4239-47. PubMed ID: 16821783
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies on a series of milnacipran analogs containing a heteroaromatic group as potent norepinephrine and serotonin transporter inhibitors.
    Vickers T; Dyck B; Tamiya J; Zhang M; Jovic F; Grey J; Fleck BA; Aparicio A; Johns M; Jin L; Tang H; Foster AC; Chen C
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3230-5. PubMed ID: 18468895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment.
    Verrico CD; Miller GM; Madras BK
    Psychopharmacology (Berl); 2007 Jan; 189(4):489-503. PubMed ID: 16220332
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological properties of new 2beta-alkyl- and 2beta-aryl-3-(substituted phenyl)tropane derivatives: stereochemical effect of C-3 on affinity and selectivity for neuronal dopamine and serotonin transporters.
    Kozikowski AP; Araldi GL; Prakash KR; Zhang M; Johnson KM
    J Med Chem; 1998 Dec; 41(25):4973-82. PubMed ID: 9836615
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of different doses of venlafaxine on serotonin and norepinephrine reuptake in healthy volunteers.
    Blier P; Saint-André E; Hébert C; de Montigny C; Lavoie N; Debonnel G
    Int J Neuropsychopharmacol; 2007 Feb; 10(1):41-50. PubMed ID: 16690005
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (Prozac).
    Andersen J; Stuhr-Hansen N; Zachariassen LG; Koldsø H; Schiøtt B; Strømgaard K; Kristensen AS
    Mol Pharmacol; 2014 May; 85(5):703-14. PubMed ID: 24516100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential physiological effects of a low dose and high doses of venlafaxine in major depression.
    Debonnel G; Saint-André E; Hébert C; de Montigny C; Lavoie N; Blier P
    Int J Neuropsychopharmacol; 2007 Feb; 10(1):51-61. PubMed ID: 16690006
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.