These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

542 related articles for article (PubMed ID: 17872445)

  • 1. Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange.
    van der Neut Kolfschoten M; Schuurman J; Losen M; Bleeker WK; Martínez-Martínez P; Vermeulen E; den Bleker TH; Wiegman L; Vink T; Aarden LA; De Baets MH; van de Winkel JG; Aalberse RC; Parren PW
    Science; 2007 Sep; 317(5844):1554-7. PubMed ID: 17872445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Immunology. Square-dancing antibodies.
    Burton DR; Wilson IA
    Science; 2007 Sep; 317(5844):1507-8. PubMed ID: 17872431
    [No Abstract]   [Full Text] [Related]  

  • 3. IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia gravis patients.
    Koneczny I; Stevens JA; De Rosa A; Huda S; Huijbers MG; Saxena A; Maestri M; Lazaridis K; Zisimopoulou P; Tzartos S; Verschuuren J; van der Maarel SM; van Damme P; De Baets MH; Molenaar PC; Vincent A; Ricciardi R; Martinez-Martinez P; Losen M
    J Autoimmun; 2017 Feb; 77():104-115. PubMed ID: 27965060
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impact of molecular processing in the hinge region of therapeutic IgG4 antibodies on disposition profiles in cynomolgus monkeys.
    Stubenrauch K; Wessels U; Regula JT; Kettenberger H; Schleypen J; Kohnert U
    Drug Metab Dispos; 2010 Jan; 38(1):84-91. PubMed ID: 19850673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Species-specific determinants in the IgG CH3 domain enable Fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength.
    Labrijn AF; Rispens T; Meesters J; Rose RJ; den Bleker TH; Loverix S; van den Bremer ET; Neijssen J; Vink T; Lasters I; Aalberse RC; Heck AJ; van de Winkel JG; Schuurman J; Parren PW
    J Immunol; 2011 Sep; 187(6):3238-46. PubMed ID: 21841137
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of immunoglobulin G4 Fab-arm exchange.
    Rispens T; Ooijevaar-de Heer P; Bende O; Aalberse RC
    J Am Chem Soc; 2011 Jul; 133(26):10302-11. PubMed ID: 21627172
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Time resolved native ion-mobility mass spectrometry to monitor dynamics of IgG4 Fab arm exchange and "bispecific" monoclonal antibody formation.
    Debaene F; Wagner-Rousset E; Colas O; Ayoub D; Corvaïa N; Van Dorsselaer A; Beck A; Cianférani S
    Anal Chem; 2013 Oct; 85(20):9785-92. PubMed ID: 24007193
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The S228P mutation prevents in vivo and in vitro IgG4 Fab-arm exchange as demonstrated using a combination of novel quantitative immunoassays and physiological matrix preparation.
    Silva JP; Vetterlein O; Jose J; Peters S; Kirby H
    J Biol Chem; 2015 Feb; 290(9):5462-9. PubMed ID: 25568323
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis.
    Vergoossen DLE; Plomp JJ; Gstöttner C; Fillié-Grijpma YE; Augustinus R; Verpalen R; Wuhrer M; Parren PWHI; Dominguez-Vega E; van der Maarel SM; Verschuuren JJ; Huijbers MG
    Proc Natl Acad Sci U S A; 2021 Mar; 118(13):. PubMed ID: 33753489
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comprehensive Analysis of the Therapeutic IgG4 Antibody Pembrolizumab: Hinge Modification Blocks Half Molecule Exchange In Vitro and In Vivo.
    Yang X; Wang F; Zhang Y; Wang L; Antonenko S; Zhang S; Zhang YW; Tabrizifard M; Ermakov G; Wiswell D; Beaumont M; Liu L; Richardson D; Shameem M; Ambrogelly A
    J Pharm Sci; 2015 Dec; 104(12):4002-4014. PubMed ID: 26308749
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of the human IgG4 C(H)3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange.
    Davies AM; Rispens T; den Bleker TH; McDonnell JM; Gould HJ; Aalberse RC; Sutton BJ
    Mol Immunol; 2013 May; 54(1):1-7. PubMed ID: 23164605
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hybrid IgG4/IgG4 Fc antibodies form upon 'Fab-arm' exchange as demonstrated by SDS-PAGE or size-exclusion chromatography.
    Rispens T; den Bleker TH; Aalberse RC
    Mol Immunol; 2010 Apr; 47(7-8):1592-4. PubMed ID: 20299101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cysteine-SILAC Mass Spectrometry Enabling the Identification and Quantitation of Scrambled Interchain Disulfide Bonds: Preservation of Native Heavy-Light Chain Pairing in Bispecific IgGs Generated by Controlled Fab-arm Exchange.
    van den Bremer ETJ; Labrijn AF; van den Boogaard R; Priem P; Scheffler K; Melis JPM; Schuurman J; Parren PWHI; de Jong RN
    Anal Chem; 2017 Oct; 89(20):10873-10882. PubMed ID: 28922593
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin G (IgG) molecules: evidence for thyroid cell damage by IgG1, but not IgG4, autoantibodies.
    Guo J; Jaume JC; Rapoport B; McLachlan SM
    J Clin Endocrinol Metab; 1997 Mar; 82(3):925-31. PubMed ID: 9062508
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis and purification of IgG4 bispecific antibodies by a mixed-mode chromatography.
    Yang X; Zhang Y; Wang F; Wang LJ; Richardson D; Shameem M; Ambrogelly A
    Anal Biochem; 2015 Sep; 484():173-9. PubMed ID: 26091837
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural determinants of unique properties of human IgG4-Fc.
    Davies AM; Rispens T; Ooijevaar-de Heer P; Gould HJ; Jefferis R; Aalberse RC; Sutton BJ
    J Mol Biol; 2014 Feb; 426(3):630-44. PubMed ID: 24211234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prevention of Fab-arm exchange and antibody reduction via stabilization of the IgG4 hinge region.
    Handlogten MW; Peng L; Christian EA; Xu W; Lin S; Venkat R; Dall'Acqua W; Ahuja S
    MAbs; 2020; 12(1):1779974. PubMed ID: 32633193
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo.
    Labrijn AF; Buijsse AO; van den Bremer ET; Verwilligen AY; Bleeker WK; Thorpe SJ; Killestein J; Polman CH; Aalberse RC; Schuurman J; van de Winkel JG; Parren PW
    Nat Biotechnol; 2009 Aug; 27(8):767-71. PubMed ID: 19620983
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Immunoglobulin G4: an odd antibody.
    Aalberse RC; Stapel SO; Schuurman J; Rispens T
    Clin Exp Allergy; 2009 Apr; 39(4):469-77. PubMed ID: 19222496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of murine anti-human Fab antibodies for use in an immunoassay for generic quantification of human Fab fragments in non-human serum samples including cynomolgus monkey samples.
    Stubenrauch K; Wessels U; Essig U; Kowalewsky F; Vogel R; Heinrich J
    J Pharm Biomed Anal; 2013 Jan; 72():208-15. PubMed ID: 23017233
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.