411 related articles for article (PubMed ID: 17878512)
1. G protein-coupled receptor trafficking in health and disease: lessons learned to prepare for therapeutic mutant rescue in vivo.
Conn PM; Ulloa-Aguirre A; Ito J; Janovick JA
Pharmacol Rev; 2007 Sep; 59(3):225-50. PubMed ID: 17878512
[TBL] [Abstract][Full Text] [Related]
2. Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease.
Ulloa-Aguirre A; Janovick JA; Brothers SP; Conn PM
Traffic; 2004 Nov; 5(11):821-37. PubMed ID: 15479448
[TBL] [Abstract][Full Text] [Related]
3. Drug development and the cellular quality control system.
Conn PM; Janovick JA
Trends Pharmacol Sci; 2009 May; 30(5):228-33. PubMed ID: 19307028
[TBL] [Abstract][Full Text] [Related]
4. G-protein-coupled receptor trafficking: understanding the chemical basis of health and disease.
Ulloa-Aguirre A; Janovick JA; Miranda AL; Conn PM
ACS Chem Biol; 2006 Nov; 1(10):631-8. PubMed ID: 17168568
[TBL] [Abstract][Full Text] [Related]
5. Functional rescue of mutant V2 vasopressin receptors causing nephrogenic diabetes insipidus by a co-expressed receptor polypeptide.
Schoneberg T; Yun J; Wenkert D; Wess J
EMBO J; 1996 Mar; 15(6):1283-91. PubMed ID: 8635461
[TBL] [Abstract][Full Text] [Related]
6. Disease-causing V(2) vasopressin receptors are retained in different compartments of the early secretory pathway.
Hermosilla R; Oueslati M; Donalies U; Schönenberger E; Krause E; Oksche A; Rosenthal W; Schülein R
Traffic; 2004 Dec; 5(12):993-1005. PubMed ID: 15522100
[TBL] [Abstract][Full Text] [Related]
7. Protein origami: therapeutic rescue of misfolded gene products.
Conn PM; Leaños-Miranda A; Janovick JA
Mol Interv; 2002 Sep; 2(5):308-16. PubMed ID: 14993385
[TBL] [Abstract][Full Text] [Related]
8. Specific ligands as pharmacological chaperones: The transport of misfolded G-protein coupled receptors to the cell surface.
Nakamura M; Yasuda D; Hirota N; Shimizu T
IUBMB Life; 2010 Jun; 62(6):453-9. PubMed ID: 20503438
[TBL] [Abstract][Full Text] [Related]
9. Derlin-1 and p97/valosin-containing protein mediate the endoplasmic reticulum-associated degradation of human V2 vasopressin receptors.
Schwieger I; Lautz K; Krause E; Rosenthal W; Wiesner B; Hermosilla R
Mol Pharmacol; 2008 Mar; 73(3):697-708. PubMed ID: 18048502
[TBL] [Abstract][Full Text] [Related]
10. Molecular and conformational features of a transport-relevant domain in the C-terminal tail of the vasopressin V(2) receptor.
Krause G; Hermosilla R; Oksche A; Rutz C; Rosenthal W; Schülein R
Mol Pharmacol; 2000 Feb; 57(2):232-42. PubMed ID: 10648632
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological chaperones correct misfolded GPCRs and rescue function: protein trafficking as a therapeutic target.
Maya-Núñez G; Ulloa-Aguirre A; Janovick JA; Conn PM
Subcell Biochem; 2012; 63():263-89. PubMed ID: 23161143
[TBL] [Abstract][Full Text] [Related]
12. Low-density lipoprotein receptor structure and folding.
Gent J; Braakman I
Cell Mol Life Sci; 2004 Oct; 61(19-20):2461-70. PubMed ID: 15526154
[TBL] [Abstract][Full Text] [Related]
13. Mutations in the human gonadotropin-releasing hormone receptor: insights into receptor biology and function.
Bédécarrats GY; Kaiser UB
Semin Reprod Med; 2007 Sep; 25(5):368-78. PubMed ID: 17710733
[TBL] [Abstract][Full Text] [Related]
14. Therapeutic rescue of misfolded mutants: validation of primary high throughput screens for identification of pharmacoperone drugs.
Janovick JA; Park BS; Conn PM
PLoS One; 2011; 6(7):e22784. PubMed ID: 21818389
[TBL] [Abstract][Full Text] [Related]
15. Molecular genetic study of congenital nephrogenic diabetes insipidus and rescue of mutant vasopressin V2 receptor by chemical chaperones.
Cheong HI; Cho HY; Park HW; Ha IS; Choi Y
Nephrology (Carlton); 2007 Apr; 12(2):113-7. PubMed ID: 17371330
[TBL] [Abstract][Full Text] [Related]
16. Therapeutic rescue of misfolded/mistrafficked mutants: automation-friendly high-throughput assays for identification of pharmacoperone drugs of GPCRs.
Smithson DC; Janovick JA; Conn PM
Methods Enzymol; 2013; 521():3-16. PubMed ID: 23351731
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological chaperone action on G-protein-coupled receptors.
Bernier V; Bichet DG; Bouvier M
Curr Opin Pharmacol; 2004 Oct; 4(5):528-33. PubMed ID: 15351360
[TBL] [Abstract][Full Text] [Related]
18. Calnexin regulated gonadotropin-releasing hormone receptor plasma membrane expression.
Brothers SP; Janovick JA; Conn PM
J Mol Endocrinol; 2006 Dec; 37(3):479-88. PubMed ID: 17170088
[TBL] [Abstract][Full Text] [Related]
19. Misrouted cell surface GnRH receptors as a disease aetiology for congenital isolated hypogonadotrophic hypogonadism.
Ulloa-Aguirre A; Janovick JA; Leaños-Miranda A; Conn PM
Hum Reprod Update; 2004; 10(2):177-92. PubMed ID: 15073146
[TBL] [Abstract][Full Text] [Related]
20. Structure-activity relations of successful pharmacologic chaperones for rescue of naturally occurring and manufactured mutants of the gonadotropin-releasing hormone receptor.
Janovick JA; Goulet M; Bush E; Greer J; Wettlaufer DG; Conn PM
J Pharmacol Exp Ther; 2003 May; 305(2):608-14. PubMed ID: 12606630
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
