167 related articles for article (PubMed ID: 17879343)
1. Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD+.
Nango E; Kumasaka T; Hirayama T; Tanaka N; Eguchi T
Proteins; 2008 Feb; 70(2):517-27. PubMed ID: 17879343
[TBL] [Abstract][Full Text] [Related]
2. Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics.
Huang Z; Kakinuma K; Eguchi T
Bioorg Chem; 2005 Apr; 33(2):82-9. PubMed ID: 15788164
[TBL] [Abstract][Full Text] [Related]
3. Active site mapping of 2-deoxy-scyllo-inosose synthase, the key starter enzyme for the biosynthesis of 2-deoxystreptamine. Mechanism-based inhibition and identification of lysine-141 as the entrapped nucleophile.
Nango E; Eguchi T; Kakinuma K
J Org Chem; 2004 Feb; 69(3):593-600. PubMed ID: 14750780
[TBL] [Abstract][Full Text] [Related]
4. Role of glutamate 243 in the active site of 2-deoxy-scyllo-inosose synthase from Bacillus circulans.
Hirayama T; Kudo F; Huang Z; Eguchi T
Bioorg Med Chem; 2007 Jan; 15(1):418-23. PubMed ID: 17035031
[TBL] [Abstract][Full Text] [Related]
5. Purification and characterization of 2-deoxy-scyllo-inosose synthase derived from Bacillus circulans. A crucial carbocyclization enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics.
Kudo F; Hosomi Y; Tamegai H; Kakinuma K
J Antibiot (Tokyo); 1999 Feb; 52(2):81-8. PubMed ID: 10344560
[TBL] [Abstract][Full Text] [Related]
6. Importance of specific hydrogen-bond donor-acceptor interactions for the key carbocycle-forming reaction catalyzed by 2-deoxy-scyllo-inosose synthase in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics.
Eguchi T; Sasaki S; Huang Z; Kakinuma K
J Org Chem; 2002 Jun; 67(12):3979-84. PubMed ID: 12054929
[TBL] [Abstract][Full Text] [Related]
7. Substrate specificity of 2-deoxy-scyllo-inosose synthase, the starter enzyme for 2-deoxystreptamine biosynthesis, toward deoxyglucose-6-phosphates and proposed mechanism.
Iwase N; Kudo F; Yamauchi N; Kakinuma K
Biosci Biotechnol Biochem; 1998 Dec; 62(12):2396-407. PubMed ID: 9972266
[TBL] [Abstract][Full Text] [Related]
8. Molecular cloning of the gene for the key carbocycle-forming enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics and its comparison with dehydroquinate synthase.
Kudo F; Tamegai H; Fujiwara T; Tagami U; Hirayama K; Kakinuma K
J Antibiot (Tokyo); 1999 Jun; 52(6):559-71. PubMed ID: 10470681
[TBL] [Abstract][Full Text] [Related]
9. Kinetic isotope effect and reaction mechanism of 2-deoxy-scyllo-inosose synthase derived from butirosin-producing Bacillus circulans.
Kudo F; Yamauchi N; Suzuki R; Kakinuma K
J Antibiot (Tokyo); 1997 May; 50(5):424-8. PubMed ID: 9207913
[TBL] [Abstract][Full Text] [Related]
10. Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
Kudo F; Yamamoto Y; Yokoyama K; Eguchi T; Kakinuma K
J Antibiot (Tokyo); 2005 Dec; 58(12):766-74. PubMed ID: 16506694
[TBL] [Abstract][Full Text] [Related]
11. Biosynthesis of 2-deoxystreptamine-containing antibiotics in Streptoalloteichus hindustanus JCM 3268: characterization of 2-deoxy-scyllo-inosose synthase.
Hirayama T; Tamegai H; Kudo F; Kojima K; Kakinuma K; Eguchi T
J Antibiot (Tokyo); 2006 Jun; 59(6):358-61. PubMed ID: 16915821
[TBL] [Abstract][Full Text] [Related]
12. Structure-based inhibitor discovery of Helicobacter pylori dehydroquinate synthase.
Liu JS; Cheng WC; Wang HJ; Chen YC; Wang WC
Biochem Biophys Res Commun; 2008 Aug; 373(1):1-7. PubMed ID: 18503755
[TBL] [Abstract][Full Text] [Related]
13. Biochemical studies on 2-deoxy-scyllo-inosose, an early intermediate in the biosynthesis of 2-deoxystreptamine. IV. A clue to the similarity of 2-deoxy-scyllo-inosose synthase to dehydroquinate synthase.
Yamauchi N; Kakinuma K
J Antibiot (Tokyo); 1993 Dec; 46(12):1916-8. PubMed ID: 8294255
[No Abstract] [Full Text] [Related]
14. Crystal structure of the reaction complex of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Thermotoga maritima refines the catalytic mechanism and indicates a new mechanism of allosteric regulation.
Shumilin IA; Bauerle R; Wu J; Woodard RW; Kretsinger RH
J Mol Biol; 2004 Aug; 341(2):455-66. PubMed ID: 15276836
[TBL] [Abstract][Full Text] [Related]
15. Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase?
Schofield LR; Anderson BF; Patchett ML; Norris GE; Jameson GB; Parker EJ
Biochemistry; 2005 Sep; 44(36):11950-62. PubMed ID: 16142893
[TBL] [Abstract][Full Text] [Related]
16. Characterization of L-glutamine:2-deoxy-scyllo-inosose aminotransferase (tbmB) from Streptomyces tenebrarius.
Kharel MK; Subba B; Lee HC; Liou K; Sohng JK
Bioorg Med Chem Lett; 2005 Jan; 15(1):89-92. PubMed ID: 15582417
[TBL] [Abstract][Full Text] [Related]
17. Efficient production of 2-deoxy-scyllo-inosose from d-glucose by metabolically engineered recombinant Escherichia coli.
Kogure T; Wakisaka N; Takaku H; Takagi M
J Biotechnol; 2007 May; 129(3):502-9. PubMed ID: 17368605
[TBL] [Abstract][Full Text] [Related]
18. One-pot enzymatic synthesis of 2-deoxy-scyllo-inosose from d-glucose and polyphosphate.
Kudo F; Mori A; Koide M; Yajima R; Takeishi R; Miyanaga A; Eguchi T
Biosci Biotechnol Biochem; 2021 Jan; 85(1):108-114. PubMed ID: 33577648
[TBL] [Abstract][Full Text] [Related]
19. Roles of a 20 kDa protein associated with a carbocycle-forming enzyme involved in aminoglycoside biosynthesis in primary and secondary metabolism.
Tamegai H; Sawada H; Nango E; Aoki R; Hirakawa H; Iino T; Eguchi T
Biosci Biotechnol Biochem; 2010; 74(6):1215-9. PubMed ID: 20530911
[TBL] [Abstract][Full Text] [Related]
20. Crystal structures of the PLP- and PMP-bound forms of BtrR, a dual functional aminotransferase involved in butirosin biosynthesis.
Popovic B; Tang X; Chirgadze DY; Huang F; Blundell TL; Spencer JB
Proteins; 2006 Oct; 65(1):220-30. PubMed ID: 16894611
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
