392 related articles for article (PubMed ID: 17881660)
21. Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells.
Fedejko-Kap B; Niemira M; Radominska-Pandya A; Mazerska Z
Xenobiotica; 2011 Dec; 41(12):1044-55. PubMed ID: 21859392
[TBL] [Abstract][Full Text] [Related]
22. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
Casabar RC; Wallace AD; Hodgson E; Rose RL
Drug Metab Dispos; 2006 Oct; 34(10):1779-85. PubMed ID: 16855053
[TBL] [Abstract][Full Text] [Related]
23. Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes.
Shiraga T; Kaneko H; Iwasaki K; Tozuka Z; Suzuki A; Hata T
Xenobiotica; 1999 Mar; 29(3):217-29. PubMed ID: 10219963
[TBL] [Abstract][Full Text] [Related]
24. Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.
Rehmel JL; Eckstein JA; Farid NA; Heim JB; Kasper SC; Kurihara A; Wrighton SA; Ring BJ
Drug Metab Dispos; 2006 Apr; 34(4):600-7. PubMed ID: 16415119
[TBL] [Abstract][Full Text] [Related]
25. Inhibition of the microsomal N-hydroxylation of 2-amino-6-nitrotoluene by a metabolite of methimazole.
Kedderis GL; Rickert DE
Biochem Biophys Res Commun; 1983 Jun; 113(2):433-8. PubMed ID: 6870866
[TBL] [Abstract][Full Text] [Related]
26. CYP-Mediated Sulfoximine Deimination of AZD6738.
Jones BC; Markandu R; Gu C; Scarfe G
Drug Metab Dispos; 2017 Nov; 45(11):1133-1138. PubMed ID: 28835442
[TBL] [Abstract][Full Text] [Related]
27. Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans.
Taniguchi-Takizawa T; Shimizu M; Kume T; Yamazaki H
Drug Metab Pharmacokinet; 2015 Feb; 30(1):64-9. PubMed ID: 25760531
[TBL] [Abstract][Full Text] [Related]
28. Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine--a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays.
Noronha G; Barrett K; Boccia A; Brodhag T; Cao J; Chow CP; Dneprovskaia E; Doukas J; Fine R; Gong X; Gritzen C; Gu H; Hanna E; Hood JD; Hu S; Kang X; Key J; Klebansky B; Kousba A; Li G; Lohse D; Mak CC; McPherson A; Palanki MS; Pathak VP; Renick J; Shi F; Soll R; Splittgerber U; Stoughton S; Tang S; Yee S; Zeng B; Zhao N; Zhu H
Bioorg Med Chem Lett; 2007 Feb; 17(3):602-8. PubMed ID: 17113292
[TBL] [Abstract][Full Text] [Related]
29. Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.
Chung WG; Park CS; Roh HK; Lee WK; Cha YN
Jpn J Pharmacol; 2000 Oct; 84(2):213-20. PubMed ID: 11128045
[TBL] [Abstract][Full Text] [Related]
30. Initial characterization of the major mouse cytochrome P450 enzymes involved in the reductive metabolism of the hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide (tirapazamine, SR 4233, WIN 59075).
Riley RJ; Hemingway SA; Graham MA; Workman P
Biochem Pharmacol; 1993 Mar; 45(5):1065-77. PubMed ID: 8461036
[TBL] [Abstract][Full Text] [Related]
31. Dehydrogenation of indoline by cytochrome P450 enzymes: a novel "aromatase" process.
Sun H; Ehlhardt WJ; Kulanthaivel P; Lanza DL; Reilly CA; Yost GS
J Pharmacol Exp Ther; 2007 Aug; 322(2):843-51. PubMed ID: 17502430
[TBL] [Abstract][Full Text] [Related]
32. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein.
Shet MS; Faulkner KM; Holmans PL; Fisher CW; Estabrook RW
Arch Biochem Biophys; 1995 Apr; 318(2):314-21. PubMed ID: 7733659
[TBL] [Abstract][Full Text] [Related]
33. The role of cytochrome P450 and cytochrome P450 reductase in the reductive bioactivation of the novel benzotriazine di-N-oxide hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233, WIN 59075) by mouse liver.
Walton MI; Wolf CR; Workman P
Biochem Pharmacol; 1992 Jul; 44(2):251-9. PubMed ID: 1642640
[TBL] [Abstract][Full Text] [Related]
34. Chiral sulfoxidation of albendazole by the flavin adenine dinucleotide-containing and cytochrome P450-dependent monooxygenases from rat liver microsomes.
Moroni P; Buronfosse T; Longin-Sauvageon C; Delatour P; Benoit E
Drug Metab Dispos; 1995 Feb; 23(2):160-5. PubMed ID: 7736906
[TBL] [Abstract][Full Text] [Related]
35. Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543.
Khojasteh-Bakht SC; Rossulek MI; Fouda HG; Prakash C
Xenobiotica; 2003 Dec; 33(12):1201-10. PubMed ID: 14742142
[TBL] [Abstract][Full Text] [Related]
36. Identification of metabolic pathways involved in the biotransformation of tolperisone by human microsomal enzymes.
Dalmadi B; Leibinger J; Szeberényi S; Borbás T; Farkas S; Szombathelyi Z; Tihanyi K
Drug Metab Dispos; 2003 May; 31(5):631-6. PubMed ID: 12695352
[TBL] [Abstract][Full Text] [Related]
37. One-electron reductive bioactivation of 2,3,5,6-tetramethylbenzoquinone by cytochrome P450.
Goeptar AR; te Koppele JM; van Maanen JM; Zoetemelk CE; Vermeulen NP
Biochem Pharmacol; 1992 Jan; 43(2):343-52. PubMed ID: 1310854
[TBL] [Abstract][Full Text] [Related]
38. Selenoxidation by flavin-containing monooxygenases as a novel pathway for beta-elimination of selenocysteine Se-conjugates.
Rooseboom M; Commandeur JN; Floor GC; Rettie AE; Vermeulen NP
Chem Res Toxicol; 2001 Jan; 14(1):127-34. PubMed ID: 11170516
[TBL] [Abstract][Full Text] [Related]
39. The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.
Mushiroda T; Douya R; Takahara E; Nagata O
Drug Metab Dispos; 2000 Oct; 28(10):1231-7. PubMed ID: 10997945
[TBL] [Abstract][Full Text] [Related]
40. One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac.
Boerma JS; Vermeulen NP; Commandeur JN
Chem Biol Interact; 2014 Jan; 207():32-40. PubMed ID: 24246759
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]