BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

530 related articles for article (PubMed ID: 17882949)

  • 1. [HERG K+ channel, the target of anti-arrhythmias drugs].
    Guan FY; Yang SJ
    Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
    Thomas D; Karle CA; Kiehn J
    Curr Pharm Des; 2006; 12(18):2271-83. PubMed ID: 16787254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking.
    Wang L; Wible BA; Wan X; Ficker E
    J Pharmacol Exp Ther; 2007 Feb; 320(2):525-34. PubMed ID: 17095614
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
    Paulussen AD; Raes A; Jongbloed RJ; Gilissen RA; Wilde AA; Snyders DJ; Smeets HJ; Aerssens J
    Cardiovasc Res; 2005 Aug; 67(3):467-75. PubMed ID: 15958262
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular determinants of high-affinity drug binding to HERG channels.
    Mitcheson JS; Perry MD
    Curr Opin Drug Discov Devel; 2003 Sep; 6(5):667-74. PubMed ID: 14579516
    [TBL] [Abstract][Full Text] [Related]  

  • 6. QT prolongation through hERG K(+) channel blockade: current knowledge and strategies for the early prediction during drug development.
    Recanatini M; Poluzzi E; Masetti M; Cavalli A; De Ponti F
    Med Res Rev; 2005 Mar; 25(2):133-66. PubMed ID: 15389727
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.
    Perrin MJ; Subbiah RN; Vandenberg JI; Hill AP
    Prog Biophys Mol Biol; 2008; 98(2-3):137-48. PubMed ID: 19027781
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular determinants of cocaine block of human ether-á-go-go-related gene potassium channels.
    Guo J; Gang H; Zhang S
    J Pharmacol Exp Ther; 2006 May; 317(2):865-74. PubMed ID: 16397089
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel.
    Karczewski J; Wang J; Kane SA; Kiss L; Koblan KS; Culberson JC; Spencer RH
    Biochem Pharmacol; 2009 May; 77(10):1602-11. PubMed ID: 19426697
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Predicting drug-hERG channel interactions that cause acquired long QT syndrome.
    Sanguinetti MC; Mitcheson JS
    Trends Pharmacol Sci; 2005 Mar; 26(3):119-24. PubMed ID: 15749156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Drug-induced QT interval prolongation--regulatory guidance and perspectives on hERG channel studies.
    Shah RR
    Novartis Found Symp; 2005; 266():251-80; discussion 280-5. PubMed ID: 16050273
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels.
    Gordon E; Lozinskaya IM; Lin Z; Semus SF; Blaney FE; Willette RN; Xu X
    Mol Pharmacol; 2008 Mar; 73(3):639-51. PubMed ID: 18042732
    [TBL] [Abstract][Full Text] [Related]  

  • 13. hERG potassium channels and cardiac arrhythmia.
    Sanguinetti MC; Tristani-Firouzi M
    Nature; 2006 Mar; 440(7083):463-9. PubMed ID: 16554806
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Refining insights into high-affinity drug binding to the human ether-à-go-go-related gene potassium channel.
    Hancox JC; James AF
    Mol Pharmacol; 2008 Jun; 73(6):1592-5. PubMed ID: 18381562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6.
    Lu Y; Mahaut-Smith MP; Huang CL; Vandenberg JI
    J Physiol; 2003 Aug; 551(Pt 1):253-62. PubMed ID: 12923204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine.
    Kim MD; Eun SY; Jo SH
    Eur J Pharmacol; 2006 Aug; 544(1-3):82-90. PubMed ID: 16860311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of HERG potassium channel function by drug action.
    Thomas D; Karle CA; Kiehn J
    Ann Med; 2004; 36 Suppl 1():41-6. PubMed ID: 15176423
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacology of cardiac potassium channels.
    Tamargo J; Caballero R; Gómez R; Valenzuela C; Delpón E
    Cardiovasc Res; 2004 Apr; 62(1):9-33. PubMed ID: 15023549
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Utility of hERG assays as surrogate markers of delayed cardiac repolarization and QT safety.
    Gintant GA; Su Z; Martin RL; Cox BF
    Toxicol Pathol; 2006; 34(1):81-90. PubMed ID: 16507548
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel structure-based virtual screening model for the hERG channel blockers.
    Du L; Li M; You Q; Xia L
    Biochem Biophys Res Commun; 2007 Apr; 355(4):889-94. PubMed ID: 17331468
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.