These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
180 related articles for article (PubMed ID: 17884340)
1. c-Cbl is not required for ERK1/2-dependent degradation of BimEL. Wiggins CM; Band H; Cook SJ Cell Signal; 2007 Dec; 19(12):2605-11. PubMed ID: 17884340 [TBL] [Abstract][Full Text] [Related]
2. CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL. Gilley R; Lochhead PA; Balmanno K; Oxley D; Clark J; Cook SJ Cell Signal; 2012 Jan; 24(1):170-80. PubMed ID: 21924351 [TBL] [Abstract][Full Text] [Related]
3. BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation. Wiggins CM; Tsvetkov P; Johnson M; Joyce CL; Lamb CA; Bryant NJ; Komander D; Shaul Y; Cook SJ J Cell Sci; 2011 Mar; 124(Pt 6):969-77. PubMed ID: 21378313 [TBL] [Abstract][Full Text] [Related]
4. Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM. Wiggins CM; Johnson M; Cook SJ Cell Signal; 2010 May; 22(5):801-8. PubMed ID: 20074640 [TBL] [Abstract][Full Text] [Related]
5. ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL. Ewings KE; Hadfield-Moorhouse K; Wiggins CM; Wickenden JA; Balmanno K; Gilley R; Degenhardt K; White E; Cook SJ EMBO J; 2007 Jun; 26(12):2856-67. PubMed ID: 17525735 [TBL] [Abstract][Full Text] [Related]
6. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. Ley R; Balmanno K; Hadfield K; Weston C; Cook SJ J Biol Chem; 2003 May; 278(21):18811-6. PubMed ID: 12646560 [TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Luciano F; Jacquel A; Colosetti P; Herrant M; Cagnol S; Pages G; Auberger P Oncogene; 2003 Oct; 22(43):6785-93. PubMed ID: 14555991 [TBL] [Abstract][Full Text] [Related]
8. Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. Qi XJ; Wildey GM; Howe PH J Biol Chem; 2006 Jan; 281(2):813-23. PubMed ID: 16282323 [TBL] [Abstract][Full Text] [Related]
9. Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL. Ley R; Hadfield K; Howes E; Cook SJ J Biol Chem; 2005 May; 280(18):17657-63. PubMed ID: 15728578 [TBL] [Abstract][Full Text] [Related]
10. Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover. Ley R; Ewings KE; Hadfield K; Howes E; Balmanno K; Cook SJ J Biol Chem; 2004 Mar; 279(10):8837-47. PubMed ID: 14681225 [TBL] [Abstract][Full Text] [Related]
11. Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM. Wickenden JA; Jin H; Johnson M; Gillings AS; Newson C; Austin M; Chell SD; Balmanno K; Pritchard CA; Cook SJ Oncogene; 2008 Dec; 27(57):7150-61. PubMed ID: 18806830 [TBL] [Abstract][Full Text] [Related]
12. The increase in BIK expression following ERK1/2 pathway inhibition is a consequence of G₁ cell-cycle arrest and not a direct effect on BIK protein stability. Sale MJ; Cook SJ Biochem J; 2014 May; 459(3):513-24. PubMed ID: 24527759 [TBL] [Abstract][Full Text] [Related]
13. Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways. Weston CR; Balmanno K; Chalmers C; Hadfield K; Molton SA; Ley R; Wagner EF; Cook SJ Oncogene; 2003 Mar; 22(9):1281-93. PubMed ID: 12618753 [TBL] [Abstract][Full Text] [Related]
14. Alternative splicing of Bim and Erk-mediated Bim(EL) phosphorylation are dispensable for hematopoietic homeostasis in vivo. Clybouw C; Merino D; Nebl T; Masson F; Robati M; O'Reilly L; Hübner A; Davis RJ; Strasser A; Bouillet P Cell Death Differ; 2012 Jun; 19(6):1060-8. PubMed ID: 22240894 [TBL] [Abstract][Full Text] [Related]
15. Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. Thompson S; Pearson AN; Ashley MD; Jessick V; Murphy BM; Gafken P; Henshall DC; Morris KT; Simon RP; Meller R J Biol Chem; 2011 Jun; 286(22):19331-9. PubMed ID: 21478148 [TBL] [Abstract][Full Text] [Related]
16. MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism. Pei XY; Dai Y; Tenorio S; Lu J; Harada H; Dent P; Grant S Blood; 2007 Sep; 110(6):2092-101. PubMed ID: 17540843 [TBL] [Abstract][Full Text] [Related]
17. Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons. Meller R; Cameron JA; Torrey DJ; Clayton CE; Ordonez AN; Henshall DC; Minami M; Schindler CK; Saugstad JA; Simon RP J Biol Chem; 2006 Mar; 281(11):7429-36. PubMed ID: 16431916 [TBL] [Abstract][Full Text] [Related]
18. Negative feedback loop in the Bim-caspase-3 axis regulating apoptosis and activity of osteoclasts. Wakeyama H; Akiyama T; Takahashi K; Amano H; Kadono Y; Nakamura M; Oshima Y; Itabe H; Nakayama KI; Nakayama K; Nakamura K; Tanaka S J Bone Miner Res; 2007 Oct; 22(10):1631-9. PubMed ID: 17592965 [TBL] [Abstract][Full Text] [Related]