211 related articles for article (PubMed ID: 17887662)
21. Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents.
Kamal A; Suresh P; Mallareddy A; Kumar BA; Reddy PV; Raju P; Tamboli JR; Shaik TB; Jain N; Kalivendi SV
Bioorg Med Chem; 2011 Apr; 19(7):2349-58. PubMed ID: 21402478
[TBL] [Abstract][Full Text] [Related]
22. Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group.
Sirisoma N; Kasibhatla S; Nguyen B; Pervin A; Wang Y; Claassen G; Tseng B; Drewe J; Cai SX
Bioorg Med Chem; 2006 Dec; 14(23):7761-73. PubMed ID: 16919962
[TBL] [Abstract][Full Text] [Related]
23. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Sarkar T; Hamel E
Bioorg Med Chem; 2008 May; 16(10):5367-76. PubMed ID: 18440234
[TBL] [Abstract][Full Text] [Related]
24. Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
Edsall AB; Mohanakrishnan AK; Yang D; Fanwick PE; Hamel E; Hanson AD; Agoston GE; Cushman M
J Med Chem; 2004 Oct; 47(21):5126-39. PubMed ID: 15456256
[TBL] [Abstract][Full Text] [Related]
25. Synthesis of new 4-thiazolidinone-, pyrazoline-, and isatin-based conjugates with promising antitumor activity.
Havrylyuk D; Zimenkovsky B; Vasylenko O; Gzella A; Lesyk R
J Med Chem; 2012 Oct; 55(20):8630-41. PubMed ID: 22992049
[TBL] [Abstract][Full Text] [Related]
26. 2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.
Chuang HY; Chang JY; Lai MJ; Kuo CC; Lee HY; Hsieh HP; Chen YJ; Chen LT; Pan WY; Liou JP
ChemMedChem; 2011 Mar; 6(3):450-6. PubMed ID: 21360819
[TBL] [Abstract][Full Text] [Related]
27. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
Pettit GR; Rhodes MR; Herald DL; Hamel E; Schmidt JM; Pettit RK
J Med Chem; 2005 Jun; 48(12):4087-99. PubMed ID: 15943482
[TBL] [Abstract][Full Text] [Related]
28. Total synthesis and anti-tubulin activity of epi-c3 analogues of cryptophycin-24.
Buck SB; Huff JK; Himes RH; Georg GI
J Med Chem; 2004 Jul; 47(14):3697-9. PubMed ID: 15214797
[TBL] [Abstract][Full Text] [Related]
29. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
Hoch U; Lynch J; Sato Y; Kashimoto S; Kajikawa F; Furutani Y; Silverman JA
Cancer Chemother Pharmacol; 2009 Jun; 64(1):53-65. PubMed ID: 18931998
[TBL] [Abstract][Full Text] [Related]
30. Synthesis, cytotoxicity, and inhibitory effects on tubulin polymerization of a new 3-heterocyclo substituted 2-styrylquinazolinones.
Raffa D; Edler MC; Daidone G; Maggio B; Merikech M; Plescia S; Schillaci D; Bai R; Hamel E
Eur J Med Chem; 2004 Apr; 39(4):299-304. PubMed ID: 15072839
[TBL] [Abstract][Full Text] [Related]
31. Cytotoxic activity and cytostatic mechanism of novel 2-arylbenzo[b]furans.
Yang H; Pang JY; Cai YC; Xu ZL; Xian LJ
J Pharm Pharmacol; 2006 Sep; 58(9):1281-7. PubMed ID: 16945188
[TBL] [Abstract][Full Text] [Related]
32. Pyrimido[4,5-c]quinolin-1(2H)-ones as a novel class of antimitotic agents: Synthesis and in vitro cytotoxic activity.
Metwally K; Pratsinis H; Kletsas D
Eur J Med Chem; 2007 Mar; 42(3):344-50. PubMed ID: 17141923
[TBL] [Abstract][Full Text] [Related]
33. Antitumor activity of new substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and study of their effect on the cell cycle.
Andreani A; Granaiola M; Leoni A; Locatelli A; Morigi R; Rambaldi M; Garaliene V; Welsh W; Arora S; Farruggia G; Masotti L
J Med Chem; 2005 Aug; 48(17):5604-7. PubMed ID: 16107161
[TBL] [Abstract][Full Text] [Related]
34. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions.
Kemnitzer W; Kuemmerle J; Jiang S; Zhang HZ; Sirisoma N; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2008 Dec; 18(23):6259-64. PubMed ID: 18952423
[TBL] [Abstract][Full Text] [Related]
35. Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: synthesis, structure-activity relationship, and action mechanism studies.
Moret V; Laras Y; Cresteil T; Aubert G; Ping DQ; Di C; Barthélémy-Requin M; Béclin C; Peyrot V; Allegro D; Rolland A; De Angelis F; Gatti E; Pierre P; Pasquini L; Petrucci E; Testa U; Kraus JL
Eur J Med Chem; 2009 Feb; 44(2):558-67. PubMed ID: 18485536
[TBL] [Abstract][Full Text] [Related]
36. Design of beta-carboline derivatives as DNA-targeting antitumor agents.
Guan H; Chen H; Peng W; Ma Y; Cao R; Liu X; Xu A
Eur J Med Chem; 2006 Oct; 41(10):1167-79. PubMed ID: 16790297
[TBL] [Abstract][Full Text] [Related]
37. Synthesis and in vitro evaluation of some isatin-thiazolidinone hybrid analogues as anti-proliferative agents.
Ramshid PK; Jagadeeshan S; Krishnan A; Mathew M; Nair SA; Pillai MR
Med Chem; 2010 Sep; 6(5):306-12. PubMed ID: 21073435
[TBL] [Abstract][Full Text] [Related]
38. Identification of novel and improved antimitotic agents derived from noscapine.
Anderson JT; Ting AE; Boozer S; Brunden KR; Crumrine C; Danzig J; Dent T; Faga L; Harrington JJ; Hodnick WF; Murphy SM; Pawlowski G; Perry R; Raber A; Rundlett SE; Stricker-Krongrad A; Wang J; Bennani YL
J Med Chem; 2005 Nov; 48(23):7096-8. PubMed ID: 16279766
[TBL] [Abstract][Full Text] [Related]
39. Dual targeting of tumour cells and host endothelial cells by novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines.
Nathwani SM; Butler S; Meegan MJ; Campiani G; Lawler M; Williams DC; Zisterer DM
Cancer Chemother Pharmacol; 2010 Jan; 65(2):289-300. PubMed ID: 19479253
[TBL] [Abstract][Full Text] [Related]
40. Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment.
Yamashita A; Norton EB; Kaplan JA; Niu C; Loganzo F; Hernandez R; Beyer CF; Annable T; Musto S; Discafani C; Zask A; Ayral-Kaloustian S
Bioorg Med Chem Lett; 2004 Nov; 14(21):5317-22. PubMed ID: 15454219
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
