136 related articles for article (PubMed ID: 17888864)
1. Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.
Endo S; Sanai M; Horie K; Matsunaga T; Ishikura S; Tajima K; El-Kabbani O; Hara A
Arch Biochem Biophys; 2007 Nov; 467(1):76-86. PubMed ID: 17888864
[TBL] [Abstract][Full Text] [Related]
2. Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme.
Ishikura S; Matsumoto K; Sanai M; Horie K; Matsunaga T; Tajima K; El-Kabbani O; Hara A
J Biochem; 2006 Jun; 139(6):1053-63. PubMed ID: 16788056
[TBL] [Abstract][Full Text] [Related]
3. Characterization of homogeneous recombinant rat ovarian 20alpha-hydroxysteroid dehydrogenase: fluorescent properties and inhibition profile.
Ma H; Penning TM
Biochem J; 1999 Aug; 341 ( Pt 3)(Pt 3):853-9. PubMed ID: 10417353
[TBL] [Abstract][Full Text] [Related]
4. Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5.
Lin SX; Shi R; Qiu W; Azzi A; Zhu DW; Dabbagh HA; Zhou M
Mol Cell Endocrinol; 2006 Mar; 248(1-2):38-46. PubMed ID: 16480815
[TBL] [Abstract][Full Text] [Related]
5. Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
Penning TM; Burczynski ME; Jez JM; Hung CF; Lin HK; Ma H; Moore M; Palackal N; Ratnam K
Biochem J; 2000 Oct; 351(Pt 1):67-77. PubMed ID: 10998348
[TBL] [Abstract][Full Text] [Related]
6. Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.
Heredia VV; Cooper WC; Kruger RG; Jin Y; Penning TM
Biochemistry; 2004 May; 43(19):5832-41. PubMed ID: 15134457
[TBL] [Abstract][Full Text] [Related]
7. Structure-function aspects and inhibitor design of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3).
Penning TM; Burczynski ME; Jez JM; Lin HK; Ma H; Moore M; Ratnam K; Palackal N
Mol Cell Endocrinol; 2001 Jan; 171(1-2):137-49. PubMed ID: 11165022
[TBL] [Abstract][Full Text] [Related]
8. Alteration of human UDP-glucuronosyltransferase UGT2B17 regio-specificity by a single amino acid substitution.
Dubois SG; Beaulieu M; Lévesque E; Hum DW; Bélanger A
J Mol Biol; 1999 May; 289(1):29-39. PubMed ID: 10339403
[TBL] [Abstract][Full Text] [Related]
9. Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine.
Schlegel BP; Ratnam K; Penning TM
Biochemistry; 1998 Aug; 37(31):11003-11. PubMed ID: 9692994
[TBL] [Abstract][Full Text] [Related]
10. Conversion of mammalian 3alpha-hydroxysteroid dehydrogenase to 20alpha-hydroxysteroid dehydrogenase using loop chimeras: changing specificity from androgens to progestins.
Ma H; Penning TM
Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11161-6. PubMed ID: 10500147
[TBL] [Abstract][Full Text] [Related]
11. Engineering steroid 5 beta-reductase activity into rat liver 3 alpha-hydroxysteroid dehydrogenase.
Jez JM; Penning TM
Biochemistry; 1998 Jul; 37(27):9695-703. PubMed ID: 9657682
[TBL] [Abstract][Full Text] [Related]
12. Molecular cloning of human type 3 3 alpha-hydroxysteroid dehydrogenase that differs from 20 alpha-hydroxysteroid dehydrogenase by seven amino acids.
Dufort I; Soucy P; Labrie F; Luu-The V
Biochem Biophys Res Commun; 1996 Nov; 228(2):474-9. PubMed ID: 8920937
[TBL] [Abstract][Full Text] [Related]
13. Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxysteroid dehydrogenase.
Penning TM
J Steroid Biochem Mol Biol; 1999; 69(1-6):211-25. PubMed ID: 10418995
[TBL] [Abstract][Full Text] [Related]
14. Characterization of a human 20alpha-hydroxysteroid dehydrogenase.
Zhang Y; Dufort I; Rheault P; Luu-The V
J Mol Endocrinol; 2000 Oct; 25(2):221-8. PubMed ID: 11013348
[TBL] [Abstract][Full Text] [Related]
15. Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate.
Lin HK; Steckelbroeck S; Fung KM; Jones AN; Penning TM
Steroids; 2004 Dec; 69(13-14):795-801. PubMed ID: 15582534
[TBL] [Abstract][Full Text] [Related]
16. Structure-function relationships in 3alpha-hydroxysteroid dehydrogenases: a comparison of the rat and human isoforms.
Penning TM; Jin Y; Heredia VV; Lewis M
J Steroid Biochem Mol Biol; 2003 Jun; 85(2-5):247-55. PubMed ID: 12943710
[TBL] [Abstract][Full Text] [Related]
17. Purification and characterization of NAD-dependent morphine 6-dehydrogenase from hamster liver cytosol, a new member of the aldo-keto reductase superfamily.
Todaka T; Yamano S; Toki S
Arch Biochem Biophys; 2000 Feb; 374(2):189-97. PubMed ID: 10666297
[TBL] [Abstract][Full Text] [Related]
18. Loop relaxation, a mechanism that explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily.
Couture JF; Legrand P; Cantin L; Labrie F; Luu-The V; Breton R
J Mol Biol; 2004 May; 339(1):89-102. PubMed ID: 15123423
[TBL] [Abstract][Full Text] [Related]
19. Cloning and expression of cDNA encoding hamster liver 3-hydroxyhexobarbital/17beta(3alpha)-hydroxysteroid dehydrogenase 1.
Takenoshita R; Nomura Y; Toki S
Chem Biol Interact; 2001 Jan; 130-132(1-3):863-70. PubMed ID: 11306101
[TBL] [Abstract][Full Text] [Related]
20. Functional characterization of the human 11 beta-hydroxysteroid dehydrogenase 1B (11 beta-HSD 1B) variant.
Blum A; Raum A; Maser E
Biochemistry; 2003 Apr; 42(14):4108-17. PubMed ID: 12680765
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
