BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 17889533)

  • 1. Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency.
    Bolchi C; Pallavicini M; Rusconi C; Diomede L; Ferri N; Corsini A; Fumagalli L; Pedretti A; Vistoli G; Valoti E
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6192-6. PubMed ID: 17889533
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase.
    Bolchi C; Pallavicini M; Bernini SK; Chiodini G; Corsini A; Ferri N; Fumagalli L; Straniero V; Valoti E
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5408-12. PubMed ID: 21802946
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Farnesyltransferase inhibitors: CAAX mimetics based on different biaryl scaffolds.
    Straniero V; Pallavicini M; Chiodini G; Ruggeri P; Fumagalli L; Bolchi C; Corsini A; Ferri N; Ricci C; Valoti E
    Bioorg Med Chem Lett; 2014 Jul; 24(13):2924-7. PubMed ID: 24821376
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New Ras CAAX mimetics: design, synthesis, antiproliferative activity, and RAS prenylation inhibition.
    Bolchi C; Pallavicini M; Fumagalli L; Ferri N; Corsini A; Rusconi C; Valoti E
    Bioorg Med Chem Lett; 2009 Sep; 19(18):5500-4. PubMed ID: 19666221
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.
    Kohring K; Wiesner J; Altenkämper M; Sakowski J; Silber K; Hillebrecht A; Haebel P; Dahse HM; Ortmann R; Jomaa H; Klebe G; Schlitzer M
    ChemMedChem; 2008 Aug; 3(8):1217-31. PubMed ID: 18470859
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Solid-phase synthesis and pharmacological evaluation of a library of peptidomimetics as potential farnesyltransferase inhibitors: an approach to new lead compounds.
    Gilleron P; Millet R; Houssin R; Wlodarczyk N; Farce A; Lemoine A; Goossens JF; Chavatte P; Pommery N; Hénichart JP
    Eur J Med Chem; 2006 Jun; 41(6):745-55. PubMed ID: 16647166
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues.
    Duez S; Coudray L; Mouray E; Grellier P; Dubois J
    Bioorg Med Chem; 2010 Jan; 18(2):543-56. PubMed ID: 20036564
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors.
    Clark MK; Scott SA; Wojtkowiak J; Chirco R; Mathieu P; Reiners JJ; Mattingly RR; Borch RF; Gibbs RA
    J Med Chem; 2007 Jul; 50(14):3274-82. PubMed ID: 17555307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New farnesyltransferase inhibitors in the phenothiazine series.
    Belei D; Dumea C; Samson A; Farce A; Dubois J; Bîcu E; Ghinet A
    Bioorg Med Chem Lett; 2012 Jul; 22(14):4517-22. PubMed ID: 22738631
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7'-azaisoindigo derivatives substituted by Sonogashira cross-coupling.
    Bouchikhi F; Anizon F; Moreau P
    Eur J Med Chem; 2009 Jun; 44(6):2705-10. PubMed ID: 19232788
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural feature study of benzofuran derivatives as farnesyltransferase inhibitors.
    Moorthy NS; Sousa SF; Ramos MJ; Fernandes PA
    J Enzyme Inhib Med Chem; 2011 Dec; 26(6):777-91. PubMed ID: 21381884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of novel diaryl ethers and their evaluation as antimitotic agents.
    In JK; Lee MS; Yang JE; Kwak JH; Lee H; Boovanahalli SK; Lee K; Kim SJ; Moon SK; Lee S; Choi NS; Ahn SK; Jung JK
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1799-802. PubMed ID: 17276056
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of o-trifluoromethylbiphenyl substituted 2-amino-nicotinonitriles as inhibitors of farnesyltransferase.
    Wang GT; Wang X; Wang W; Hasvold LA; Sullivan G; Hutchins CW; O'Conner S; Gentiles R; Sowin T; Cohen J; Gu WZ; Zhang H; Rosenberg SH; Sham HL
    Bioorg Med Chem Lett; 2005 Jan; 15(1):153-8. PubMed ID: 15582430
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3D-QSAR with the aid of pharmacophore search and docking-based alignments for farnesyltransferase inhibitors.
    Vaidya M; Weigt M; Wiese M
    Eur J Med Chem; 2009 Oct; 44(10):4070-82. PubMed ID: 19515462
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiproliferative action of cudraflavone B, isolated from Cudrania tricuspidata, through the downregulation of pRb phosphorylation in aortic smooth muscle cell proliferation signaling.
    Kim TJ; Han HJ; Lim Y; Song MC; Kim J; Hong JT; Yoo HS; Pyo MY; Hwang BY; Lee MK; Yun YP
    J Cardiovasc Pharmacol; 2009 Apr; 53(4):341-8. PubMed ID: 19295442
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group.
    Tanaka A; Radwan MO; Hamasaki A; Ejima A; Obata E; Koga R; Tateishi H; Okamoto Y; Fujita M; Nakao M; Umezawa K; Tamanoi F; Otsuka M
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3862-3866. PubMed ID: 28666734
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties.
    Zhang M; Nguyen JT; Kumada HO; Kimura T; Cheng M; Hayashi Y; Kiso Y
    Bioorg Med Chem; 2008 May; 16(10):5795-802. PubMed ID: 18400502
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 3D-QSAR studies of heterocyclic quinones with inhibitory activity on vascular smooth muscle cell proliferation using pharmacophore-based alignment.
    Ryu CK; Lee Y; Park SG; You HJ; Lee RY; Lee SY; Choi S
    Bioorg Med Chem; 2008 Nov; 16(22):9772-9. PubMed ID: 18930405
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteasome inhibition by peptide-semicarbazones.
    Leban J; Blisse M; Krauss B; Rath S; Baumgartner R; Seifert MH
    Bioorg Med Chem; 2008 Apr; 16(8):4579-88. PubMed ID: 18313310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Omega-alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: a study of chain-length and stereochemical dependence.
    Hanessian S; Auzzas L; Giannini G; Marzi M; Cabri W; Barbarino M; Vesci L; Pisano C
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6261-5. PubMed ID: 17892933
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.