BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 17893561)

  • 1. Redirected activity of human antitumor chimeric immune receptors is governed by antigen and receptor expression levels and affinity of interaction.
    Turatti F; Figini M; Balladore E; Alberti P; Casalini P; Marks JD; Canevari S; Mezzanzanica D
    J Immunother; 2007 Oct; 30(7):684-93. PubMed ID: 17893561
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor.
    Turatti F; Figini M; Alberti P; Willemsen RA; Canevari S; Mezzanzanica D
    J Gene Med; 2005 Feb; 7(2):158-70. PubMed ID: 15538730
    [TBL] [Abstract][Full Text] [Related]  

  • 3. T-cell killing of heterogenous tumor or viral targets with bispecific chimeric immune receptors.
    Patel SD; Moskalenko M; Tian T; Smith D; McGuinness R; Chen L; Winslow GA; Kashmiri S; Schlom J; Stanners CP; Finer MH; McArthur JG
    Cancer Gene Ther; 2000 Aug; 7(8):1127-34. PubMed ID: 10975673
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel bispecific tetravalent antibody fusion protein to target costimulatory activity for T-cell activation to tumor cells overexpressing ErbB2/HER2.
    Biburger M; Weth R; Wels WS
    J Mol Biol; 2005 Mar; 346(5):1299-311. PubMed ID: 15713482
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antigen-specific cytolysis by neutrophils and NK cells expressing chimeric immune receptors bearing zeta or gamma signaling domains.
    Roberts MR; Cooke KS; Tran AC; Smith KA; Lin WY; Wang M; Dull TJ; Farson D; Zsebo KM; Finer MH
    J Immunol; 1998 Jul; 161(1):375-84. PubMed ID: 9647246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model.
    Yoon SH; Lee JM; Cho HI; Kim EK; Kim HS; Park MY; Kim TG
    Cancer Gene Ther; 2009 Jun; 16(6):489-97. PubMed ID: 19096447
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A fully human chimeric immune receptor for retargeting T-cells to CEA-expressing tumor cells.
    Shibaguchi H; Luo NX; Kuroki M; Zhao J; Huang J; Hachimine K; Kinugasa T; Kuroki M
    Anticancer Res; 2006; 26(6A):4067-72. PubMed ID: 17195459
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A spacer region between the single chain antibody- and the CD3 zeta-chain domain of chimeric T cell receptor components is required for efficient ligand binding and signaling activity.
    Moritz D; Groner B
    Gene Ther; 1995 Oct; 2(8):539-46. PubMed ID: 8593604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells.
    Moeller M; Haynes NM; Trapani JA; Teng MW; Jackson JT; Tanner JE; Cerutti L; Jane SM; Kershaw MH; Smyth MJ; Darcy PK
    Cancer Gene Ther; 2004 May; 11(5):371-9. PubMed ID: 15060573
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bypassing immunization: optimized design of "designer T cells" against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA.
    Nolan KF; Yun CO; Akamatsu Y; Murphy JC; Leung SO; Beecham EJ; Junghans RP
    Clin Cancer Res; 1999 Dec; 5(12):3928-41. PubMed ID: 10632322
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting of T cells to CEA-expressing tumor cells by chimeric immune receptors with a highly specific single-chain anti-CEA activity.
    Arakawa F; Shibaguchi H; Xu Z; Kuroki M
    Anticancer Res; 2002; 22(6C):4285-9. PubMed ID: 12553071
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Manufacturing of gene-modified cytotoxic T lymphocytes for autologous cellular therapy for lymphoma.
    Cooper LJ; Ausubel L; Gutierrez M; Stephan S; Shakeley R; Olivares S; Serrano LM; Burton L; Jensen MC; Forman SJ; DiGiusto DL
    Cytotherapy; 2006; 8(2):105-17. PubMed ID: 16698684
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytolysis of tumor cells expressing the Neu/erbB-2, erbB-3, and erbB-4 receptors by genetically targeted naive T lymphocytes.
    Altenschmidt U; Kahl R; Moritz D; Schnierle BS; Gerstmayer B; Wels W; Groner B
    Clin Cancer Res; 1996 Jun; 2(6):1001-8. PubMed ID: 9816261
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A single-chain IL-12 IgG3 antibody fusion protein retains antibody specificity and IL-12 bioactivity and demonstrates antitumor activity.
    Peng LS; Penichet ML; Morrison SL
    J Immunol; 1999 Jul; 163(1):250-8. PubMed ID: 10384123
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impact of chimeric immune receptor extracellular protein domains on T cell function.
    Patel SD; Moskalenko M; Smith D; Maske B; Finer MH; McArthur JG
    Gene Ther; 1999 Mar; 6(3):412-9. PubMed ID: 10435091
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice.
    Wei H; Wang S; Zhang D; Hou S; Qian W; Li B; Guo H; Kou G; He J; Wang H; Guo Y
    Clin Cancer Res; 2009 Jul; 15(14):4612-21. PubMed ID: 19584156
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effector cell recruitment with novel Fv-based dual-affinity re-targeting protein leads to potent tumor cytolysis and in vivo B-cell depletion.
    Johnson S; Burke S; Huang L; Gorlatov S; Li H; Wang W; Zhang W; Tuaillon N; Rainey J; Barat B; Yang Y; Jin L; Ciccarone V; Moore PA; Koenig S; Bonvini E
    J Mol Biol; 2010 Jun; 399(3):436-49. PubMed ID: 20382161
    [TBL] [Abstract][Full Text] [Related]  

  • 18. T cell activation by recombinant FcepsilonRI gamma-chain immune receptors: an extracellular spacer domain impairs antigen-dependent T cell activation but not antigen recognition.
    Hombach A; Heuser C; Gerken M; Fischer B; Lewalter K; Diehl V; Pohl C; Abken H
    Gene Ther; 2000 Jun; 7(12):1067-75. PubMed ID: 10871757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Construction of expression vector of hTERT- hIL18 fusion gene and induction of cytotoxic T lymphocyte response against hTERT.
    Tong XM; Zheng SE; Bader A; Yao HP; Wu NP; Altmeyer P; Brockmeyer NH; Jin J
    Eur J Med Res; 2008 Jan; 13(1):7-14. PubMed ID: 18226991
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors.
    Stancovski I; Schindler DG; Waks T; Yarden Y; Sela M; Eshhar Z
    J Immunol; 1993 Dec; 151(11):6577-82. PubMed ID: 7902379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.