BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 17898046)

  • 1. A monoclonal Fab derived from a human nonimmune phage library reveals a new epitope on gp41 and neutralizes diverse human immunodeficiency virus type 1 strains.
    Gustchina E; Louis JM; Lam SN; Bewley CA; Clore GM
    J Virol; 2007 Dec; 81(23):12946-53. PubMed ID: 17898046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41.
    Gustchina E; Bewley CA; Clore GM
    J Virol; 2008 Oct; 82(20):10032-41. PubMed ID: 18667502
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization and HIV-1 fusion inhibitory properties of monoclonal Fabs obtained from a human non-immune phage library selected against diverse epitopes of the ectodomain of HIV-1 gp41.
    Louis JM; Bewley CA; Gustchina E; Aniana A; Clore GM
    J Mol Biol; 2005 Nov; 353(5):945-51. PubMed ID: 16216270
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10.
    Nelson JD; Brunel FM; Jensen R; Crooks ET; Cardoso RM; Wang M; Hessell A; Wilson IA; Binley JM; Dawson PE; Burton DR; Zwick MB
    J Virol; 2007 Apr; 81(8):4033-43. PubMed ID: 17287272
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth.
    Gustchina E; Louis JM; Frisch C; Ylera F; Lechner A; Bewley CA; Clore GM
    Virology; 2009 Oct; 393(1):112-9. PubMed ID: 19695655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies.
    Choudhry V; Zhang MY; Sidorov IA; Louis JM; Harris I; Dimitrov AS; Bouma P; Cham F; Choudhary A; Rybak SM; Fouts T; Montefiori DC; Broder CC; Quinnan GV; Dimitrov DS
    Virology; 2007 Jun; 363(1):79-90. PubMed ID: 17306322
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.
    Stiegler G; Kunert R; Purtscher M; Wolbank S; Voglauer R; Steindl F; Katinger H
    AIDS Res Hum Retroviruses; 2001 Dec; 17(18):1757-65. PubMed ID: 11788027
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
    Nelson JD; Kinkead H; Brunel FM; Leaman D; Jensen R; Louis JM; Maruyama T; Bewley CA; Bowdish K; Clore GM; Dawson PE; Frederickson S; Mage RG; Richman DD; Burton DR; Zwick MB
    Virology; 2008 Jul; 377(1):170-83. PubMed ID: 18499210
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6.
    Bryson S; Julien JP; Isenman DE; Kunert R; Katinger H; Pai EF
    J Mol Biol; 2008 Oct; 382(4):910-9. PubMed ID: 18692506
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Binding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp41 in the pre-hairpin and six-helix bundle conformations.
    Louis JM; Aniana A; Lohith K; Sayer JM; Roche J; Bewley CA; Clore GM
    PLoS One; 2014; 9(8):e104683. PubMed ID: 25105806
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.
    Zwick MB; Jensen R; Church S; Wang M; Stiegler G; Kunert R; Katinger H; Burton DR
    J Virol; 2005 Jan; 79(2):1252-61. PubMed ID: 15613352
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens.
    Zhang MY; Vu BK; Choudhary A; Lu H; Humbert M; Ong H; Alam M; Ruprecht RM; Quinnan G; Jiang S; Montefiori DC; Mascola JR; Broder CC; Haynes BF; Dimitrov DS
    J Virol; 2008 Jul; 82(14):6869-79. PubMed ID: 18480433
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Competitive antigen panning for selection of HIV-1 neutralizing human monoclonal antibodies specific for gp41.
    Zhang MY; Dimitrov DS
    Methods Mol Biol; 2009; 525():175-86, xv. PubMed ID: 19252830
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction between a Fab fragment against gp41 of human immunodeficiency virus 1 and its peptide epitope: characterization using a peptide epitope library and molecular modeling.
    Stigler RD; Rüker F; Katinger D; Elliott G; Höhne W; Henklein P; Ho JX; Keeling K; Carter DC; Nugel E
    Protein Eng; 1995 May; 8(5):471-9. PubMed ID: 8532669
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding.
    Binley JM; Ditzel HJ; Barbas CF; Sullivan N; Sodroski J; Parren PW; Burton DR
    AIDS Res Hum Retroviruses; 1996 Jul; 12(10):911-24. PubMed ID: 8798976
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multifaceted consequences of anti-gp41 monoclonal antibody 2F5 binding to HIV type 1 virions.
    Neurath AR; Strick N; Lin K; Jiang S
    AIDS Res Hum Retroviruses; 1995 Jun; 11(6):687-96. PubMed ID: 7576928
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recognition by human monoclonal antibodies of free and complexed peptides representing the prefusogenic and fusogenic forms of human immunodeficiency virus type 1 gp41.
    Gorny MK; Zolla-Pazner S
    J Virol; 2000 Jul; 74(13):6186-92. PubMed ID: 10846104
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions of HIV-1 antibodies 2F5 and 4E10 with a gp41 epitope prebound to host and viral membrane model systems.
    Veiga AS; Pattenden LK; Fletcher JM; Castanho MA; Aguilar MI
    Chembiochem; 2009 Apr; 10(6):1032-44. PubMed ID: 19283693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1.
    Purtscher M; Trkola A; Gruber G; Buchacher A; Predl R; Steindl F; Tauer C; Berger R; Barrett N; Jungbauer A
    AIDS Res Hum Retroviruses; 1994 Dec; 10(12):1651-8. PubMed ID: 7888224
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deletion of fusion peptide or destabilization of fusion core of HIV gp41 enhances antigenicity and immunogenicity of 4E10 epitope.
    Li J; Chen X; Jiang S; Chen YH
    Biochem Biophys Res Commun; 2008 Nov; 376(1):60-4. PubMed ID: 18762167
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.