BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 17901128)

  • 1. Fibroblast growth factor receptor 1 (FGFR1) tyrosine phosphorylation regulates binding of FGFR substrate 2alpha (FRS2alpha) but not FRS2 to the receptor.
    Zhang Y; McKeehan K; Lin Y; Zhang J; Wang F
    Mol Endocrinol; 2008 Jan; 22(1):167-75. PubMed ID: 17901128
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.
    Ong SH; Guy GR; Hadari YR; Laks S; Gotoh N; Schlessinger J; Lax I
    Mol Cell Biol; 2000 Feb; 20(3):979-89. PubMed ID: 10629055
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ternary complex formation of EphA4, FGFR and FRS2α plays an important role in the proliferation of embryonic neural stem/progenitor cells.
    Sawada T; Jing X; Zhang Y; Shimada E; Yokote H; Miyajima M; Sakaguchi K
    Genes Cells; 2010 Mar; 15(3):297-311. PubMed ID: 20184660
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Compartmentalizing proximal FGFR1 signaling in ovine placental artery endothelial cell caveolae.
    Feng L; Zhang HH; Wang W; Zheng J; Chen DB
    Biol Reprod; 2012 Aug; 87(2):40. PubMed ID: 22674390
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina.
    Gotoh N; Ito M; Yamamoto S; Yoshino I; Song N; Wang Y; Lax I; Schlessinger J; Shibuya M; Lang RA
    Proc Natl Acad Sci U S A; 2004 Dec; 101(49):17144-9. PubMed ID: 15569927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins.
    Gotoh N
    Cancer Sci; 2008 Jul; 99(7):1319-25. PubMed ID: 18452557
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation.
    Hadari YR; Kouhara H; Lax I; Schlessinger J
    Mol Cell Biol; 1998 Jul; 18(7):3966-73. PubMed ID: 9632781
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α.
    Barylko B; Chen YJ; Hennen J; Angert I; Chen Y; Mueller JD; Sun HQ; Taylor CA; Liou J; Yin H; Albanesi JP
    Biochemistry; 2019 Jun; 58(25):2809-2813. PubMed ID: 31184863
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanisms.
    Zhou L; Talebian A; Meakin SO
    J Mol Neurosci; 2015 Mar; 55(3):663-77. PubMed ID: 25159185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors.
    Lax I; Wong A; Lamothe B; Lee A; Frost A; Hawes J; Schlessinger J
    Mol Cell; 2002 Oct; 10(4):709-19. PubMed ID: 12419216
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.
    Li H; Tao C; Cai Z; Hertzler-Schaefer K; Collins TN; Wang F; Feng GS; Gotoh N; Zhang X
    J Cell Sci; 2014 Feb; 127(Pt 3):571-82. PubMed ID: 24284065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction.
    Kurokawa K; Iwashita T; Murakami H; Hayashi H; Kawai K; Takahashi M
    Oncogene; 2001 Apr; 20(16):1929-38. PubMed ID: 11360177
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.
    Cross MJ; Lu L; Magnusson P; Nyqvist D; Holmqvist K; Welsh M; Claesson-Welsh L
    Mol Biol Cell; 2002 Aug; 13(8):2881-93. PubMed ID: 12181353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway.
    Zhou W; Feng X; Wu Y; Benge J; Zhang Z; Chen Z
    Cell Res; 2009 Oct; 19(10):1165-77. PubMed ID: 19652666
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural insights into FRS2α PTB domain recognition by neurotrophin receptor TrkB.
    Zeng L; Kuti M; Mujtaba S; Zhou MM
    Proteins; 2014 Jul; 82(7):1534-41. PubMed ID: 24470253
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins.
    Ong SH; Hadari YR; Gotoh N; Guy GR; Schlessinger J; Lax I
    Proc Natl Acad Sci U S A; 2001 May; 98(11):6074-9. PubMed ID: 11353842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular networks in FGF signaling: flotillin-1 and cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2.
    Tomasovic A; Traub S; Tikkanen R
    PLoS One; 2012; 7(1):e29739. PubMed ID: 22235335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells.
    Klint P; Kanda S; Claesson-Welsh L
    J Biol Chem; 1995 Oct; 270(40):23337-44. PubMed ID: 7559490
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.
    Manuvakhova M; Thottassery JV; Hays S; Qu Z; Rentz SS; Westbrook L; Kern FG
    Oncogene; 2006 Sep; 25(44):6003-14. PubMed ID: 16682955
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression.
    Li Q; Alsaidan OA; Ma Y; Kim S; Liu J; Albers T; Liu K; Beharry Z; Zhao S; Wang F; Lebedyeva I; Cai H
    J Biol Chem; 2018 Apr; 293(17):6434-6448. PubMed ID: 29540482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.