These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

411 related articles for article (PubMed ID: 17901249)

  • 1. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome.
    Kirsammer G; Jilani S; Liu H; Davis E; Gurbuxani S; Le Beau MM; Crispino JD
    Blood; 2008 Jan; 111(2):767-75. PubMed ID: 17901249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mouse models of Down syndrome: gene content and consequences.
    Gupta M; Dhanasekaran AR; Gardiner KJ
    Mamm Genome; 2016 Dec; 27(11-12):538-555. PubMed ID: 27538963
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trisomy of Erg is required for myeloproliferation in a mouse model of Down syndrome.
    Ng AP; Hyland CD; Metcalf D; Carmichael CL; Loughran SJ; Di Rago L; Kile BT; Alexander WS
    Blood; 2010 May; 115(19):3966-9. PubMed ID: 20007548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Early lineage priming by trisomy of Erg leads to myeloproliferation in a Down syndrome model.
    Ng AP; Hu Y; Metcalf D; Hyland CD; Ierino H; Phipson B; Wu D; Baldwin TM; Kauppi M; Kiu H; Di Rago L; Hilton DJ; Smyth GK; Alexander WS
    PLoS Genet; 2015 May; 11(5):e1005211. PubMed ID: 25973911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome.
    Malinge S; Bliss-Moreau M; Kirsammer G; Diebold L; Chlon T; Gurbuxani S; Crispino JD
    J Clin Invest; 2012 Mar; 122(3):948-62. PubMed ID: 22354171
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome.
    Kahlem P; Sultan M; Herwig R; Steinfath M; Balzereit D; Eppens B; Saran NG; Pletcher MT; South ST; Stetten G; Lehrach H; Reeves RH; Yaspo ML
    Genome Res; 2004 Jul; 14(7):1258-67. PubMed ID: 15231742
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts.
    Thomas JR; Sloan K; Cave K; Wallace JM; Roper RJ
    Genes (Basel); 2021 Oct; 12(11):. PubMed ID: 34828335
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21.
    Rainis L; Bercovich D; Strehl S; Teigler-Schlegel A; Stark B; Trka J; Amariglio N; Biondi A; Muler I; Rechavi G; Kempski H; Haas OA; Izraeli S
    Blood; 2003 Aug; 102(3):981-6. PubMed ID: 12649131
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transient myeloproliferative disorder with partial trisomy 21.
    Takahashi T; Inoue A; Yoshimoto J; Kanamitsu K; Taki T; Imada M; Yamada M; Ninomiya S; Toki T; Terui K; Ito E; Shimada A
    Pediatr Blood Cancer; 2015 Nov; 62(11):2021-4. PubMed ID: 26138905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia.
    Klusmann JH; Li Z; Böhmer K; Maroz A; Koch ML; Emmrich S; Godinho FJ; Orkin SH; Reinhardt D
    Genes Dev; 2010 Mar; 24(5):478-90. PubMed ID: 20194440
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model.
    Polk RC; Gergics P; Steimle JD; Li H; Moskowitz IP; Camper SA; Reeves RH
    BMC Dev Biol; 2015 Jul; 15():30. PubMed ID: 26208718
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.
    Amano K; Sago H; Uchikawa C; Suzuki T; Kotliarova SE; Nukina N; Epstein CJ; Yamakawa K
    Hum Mol Genet; 2004 Jul; 13(13):1333-40. PubMed ID: 15138197
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.
    Raveau M; Lignon JM; Nalesso V; Duchon A; Groner Y; Sharp AJ; Dembele D; Brault V; Hérault Y
    PLoS Genet; 2012 May; 8(5):e1002724. PubMed ID: 22693452
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome.
    Alford KA; Slender A; Vanes L; Li Z; Fisher EM; Nizetic D; Orkin SH; Roberts I; Tybulewicz VL
    Blood; 2010 Apr; 115(14):2928-37. PubMed ID: 20154221
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome.
    Kleschevnikov AM; Yu J; Kim J; Lysenko LV; Zeng Z; Yu YE; Mobley WC
    Neurobiol Dis; 2017 Jul; 103():1-10. PubMed ID: 28342823
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome.
    De Vita S; Canzonetta C; Mulligan C; Delom F; Groet J; Baldo C; Vanes L; Dagna-Bricarelli F; Hoischen A; Veltman J; Fisher EM; Tybulewicz VL; Nizetic D
    Oncogene; 2010 Nov; 29(46):6102-14. PubMed ID: 20697343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hematopoietic Stem Cells from Ts65Dn Mice Are Deficient in the Repair of DNA Double-Strand Breaks.
    Wang Y; Chang J; Shao L; Feng W; Luo Y; Chow M; Du W; Meng A; Zhou D
    Radiat Res; 2016 Jun; 185(6):630-7. PubMed ID: 27243896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sexually dimorphic DYRK1A overexpression on postnatal day 15 in the Ts65Dn mouse model of Down syndrome: Effects of pharmacological targeting on behavioral phenotypes.
    Hawley LE; Prochaska F; Stringer M; Goodlett CR; Roper RJ
    Pharmacol Biochem Behav; 2022 Jun; 217():173404. PubMed ID: 35576991
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential effects of trisomy on brain shape and volume in related aneuploid mouse models.
    Aldridge K; Reeves RH; Olson LE; Richtsmeier JT
    Am J Med Genet A; 2007 May; 143A(10):1060-70. PubMed ID: 17431903
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct clones are associated with the development of transient myeloproliferative disorder and acute megakaryocytic leukemia in a patient with Down syndrome.
    Kanegane H; Watanabe S; Nomura K; Xu G; Ito E; Miyawaki T
    Int J Hematol; 2007 Oct; 86(3):250-2. PubMed ID: 17988992
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.