246 related articles for article (PubMed ID: 17902043)
1. Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range.
Majumder P; Raychaudhuri S; Chattopadhyay B; Bhattacharyya NP
Cell Mol Neurobiol; 2007 Dec; 27(8):1127-45. PubMed ID: 17902043
[TBL] [Abstract][Full Text] [Related]
2. Effects of overexpression of huntingtin proteins on mitochondrial integrity.
Wang H; Lim PJ; Karbowski M; Monteiro MJ
Hum Mol Genet; 2009 Feb; 18(4):737-52. PubMed ID: 19039036
[TBL] [Abstract][Full Text] [Related]
3. Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1.
Majumder P; Chattopadhyay B; Mazumder A; Das P; Bhattacharyya NP
Neurobiol Dis; 2006 May; 22(2):242-56. PubMed ID: 16364650
[TBL] [Abstract][Full Text] [Related]
4. HYPK, a Huntingtin interacting protein, reduces aggregates and apoptosis induced by N-terminal Huntingtin with 40 glutamines in Neuro2a cells and exhibits chaperone-like activity.
Raychaudhuri S; Sinha M; Mukhopadhyay D; Bhattacharyya NP
Hum Mol Genet; 2008 Jan; 17(2):240-55. PubMed ID: 17947297
[TBL] [Abstract][Full Text] [Related]
5. Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.
Clemens LE; Weber JJ; Wlodkowski TT; Yu-Taeger L; Michaud M; Calaminus C; Eckert SH; Gaca J; Weiss A; Magg JC; Jansson EK; Eckert GP; Pichler BJ; Bordet T; Pruss RM; Riess O; Nguyen HP
Brain; 2015 Dec; 138(Pt 12):3632-53. PubMed ID: 26490331
[TBL] [Abstract][Full Text] [Related]
6. Significantly differential diffusion of neuropathological aggregates in the brain of transgenic mice carrying N-terminal mutant huntingtin fused with green fluorescent protein.
Cheng PH; Li CL; Her LS; Chang YF; Chan AW; Chen CM; Yang SH
Brain Struct Funct; 2013 Jan; 218(1):283-94. PubMed ID: 22422149
[TBL] [Abstract][Full Text] [Related]
7. Expanded huntingtin activates the c-Jun terminal kinase/c-Jun pathway prior to aggregate formation in striatal neurons in culture.
Garcia M; Charvin D; Caboche J
Neuroscience; 2004; 127(4):859-70. PubMed ID: 15312898
[TBL] [Abstract][Full Text] [Related]
8. Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.
Kim YJ; Yi Y; Sapp E; Wang Y; Cuiffo B; Kegel KB; Qin ZH; Aronin N; DiFiglia M
Proc Natl Acad Sci U S A; 2001 Oct; 98(22):12784-9. PubMed ID: 11675509
[TBL] [Abstract][Full Text] [Related]
9. Adenovirus-mediated silencing of huntingtin expression by shRNA.
Huang B; Kochanek S
Hum Gene Ther; 2005 May; 16(5):618-26. PubMed ID: 15916486
[TBL] [Abstract][Full Text] [Related]
10. Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates.
Yan Y; Peng D; Tian J; Chi J; Tan J; Yin X; Pu J; Xia K; Zhang B
Sci China Life Sci; 2011 Apr; 54(4):342-50. PubMed ID: 21509658
[TBL] [Abstract][Full Text] [Related]
11. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release.
Jana NR; Zemskov EA; Wang Gh ; Nukina N
Hum Mol Genet; 2001 May; 10(10):1049-59. PubMed ID: 11331615
[TBL] [Abstract][Full Text] [Related]
12. Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.
Banerjee M; Datta M; Bhattacharyya NP
Int J Biochem Cell Biol; 2017 Jan; 82():1-9. PubMed ID: 27840155
[TBL] [Abstract][Full Text] [Related]
13. Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Sathasivam K; Neueder A; Gipson TA; Landles C; Benjamin AC; Bondulich MK; Smith DL; Faull RL; Roos RA; Howland D; Detloff PJ; Housman DE; Bates GP
Proc Natl Acad Sci U S A; 2013 Feb; 110(6):2366-70. PubMed ID: 23341618
[TBL] [Abstract][Full Text] [Related]
14. Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.
Busch A; Engemann S; Lurz R; Okazawa H; Lehrach H; Wanker EE
J Biol Chem; 2003 Oct; 278(42):41452-61. PubMed ID: 12888569
[TBL] [Abstract][Full Text] [Related]
15. High-capacity adenoviral vector-mediated reduction of huntingtin aggregate load in vitro and in vivo.
Huang B; Schiefer J; Sass C; Landwehrmeyer GB; Kosinski CM; Kochanek S
Hum Gene Ther; 2007 Apr; 18(4):303-11. PubMed ID: 17472569
[TBL] [Abstract][Full Text] [Related]
16. A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity.
Bañez-Coronel M; Porta S; Kagerbauer B; Mateu-Huertas E; Pantano L; Ferrer I; Guzmán M; Estivill X; Martí E
PLoS Genet; 2012; 8(2):e1002481. PubMed ID: 22383888
[TBL] [Abstract][Full Text] [Related]
17. Parent-of-origin differences of mutant HTT CAG repeat instability in Huntington's disease.
Aziz NA; van Belzen MJ; Coops ID; Belfroid RD; Roos RA
Eur J Med Genet; 2011; 54(4):e413-8. PubMed ID: 21540131
[TBL] [Abstract][Full Text] [Related]
18. Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.
Hansson O; Castilho RF; Korhonen L; Lindholm D; Bates GP; Brundin P
J Neurochem; 2001 Aug; 78(4):694-703. PubMed ID: 11520890
[TBL] [Abstract][Full Text] [Related]
19. Extended polyglutamine repeats trigger a feedback loop involving the mitochondrial complex III, the proteasome and huntingtin aggregates.
Fukui H; Moraes CT
Hum Mol Genet; 2007 Apr; 16(7):783-97. PubMed ID: 17356014
[TBL] [Abstract][Full Text] [Related]
20. Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis.
Li SH; Lam S; Cheng AL; Li XJ
Hum Mol Genet; 2000 Nov; 9(19):2859-67. PubMed ID: 11092762
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
