350 related articles for article (PubMed ID: 17902053)
1. Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.
Puig T; Vázquez-Martín A; Relat J; Pétriz J; Menéndez JA; Porta R; Casals G; Marrero PF; Haro D; Brunet J; Colomer R
Breast Cancer Res Treat; 2008 Jun; 109(3):471-9. PubMed ID: 17902053
[TBL] [Abstract][Full Text] [Related]
2. Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals.
Puig T; Relat J; Marrero PF; Haro D; Brunet J; Colomer R
Anticancer Res; 2008; 28(6A):3671-6. PubMed ID: 19189648
[TBL] [Abstract][Full Text] [Related]
3. Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.
Zhou W; Simpson PJ; McFadden JM; Townsend CA; Medghalchi SM; Vadlamudi A; Pinn ML; Ronnett GV; Kuhajda FP
Cancer Res; 2003 Nov; 63(21):7330-7. PubMed ID: 14612531
[TBL] [Abstract][Full Text] [Related]
4. Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.
Relat J; Blancafort A; Oliveras G; Cufí S; Haro D; Marrero PF; Puig T
BMC Cancer; 2012 Jul; 12():280. PubMed ID: 22769244
[TBL] [Abstract][Full Text] [Related]
5. RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells.
Menendez JA; Lupu R
Int J Mol Med; 2005 Jan; 15(1):33-40. PubMed ID: 15583825
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.
Menendez JA; Colomer R; Lupu R
Med Hypotheses; 2005; 64(2):337-41. PubMed ID: 15607568
[TBL] [Abstract][Full Text] [Related]
7. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
Menendez JA; Ropero S; Mehmi I; Atlas E; Colomer R; Lupu R
Int J Oncol; 2004 Jun; 24(6):1369-83. PubMed ID: 15138577
[TBL] [Abstract][Full Text] [Related]
8. Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
Bentebibel A; Sebastián D; Herrero L; López-Viñas E; Serra D; Asins G; Gómez-Puertas P; Hegardt FG
Biochemistry; 2006 Apr; 45(14):4339-50. PubMed ID: 16584169
[TBL] [Abstract][Full Text] [Related]
9. Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling.
Pan MH; Lin CC; Lin JK; Chen WJ
J Agric Food Chem; 2007 Jun; 55(13):5030-7. PubMed ID: 17539658
[TBL] [Abstract][Full Text] [Related]
10. Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells.
Vazquez-Martin A; Colomer R; Brunet J; Menendez JA
Int J Oncol; 2007 Oct; 31(4):769-76. PubMed ID: 17786307
[TBL] [Abstract][Full Text] [Related]
11. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
Thupari JN; Pinn ML; Kuhajda FP
Biochem Biophys Res Commun; 2001 Jul; 285(2):217-23. PubMed ID: 11444828
[TBL] [Abstract][Full Text] [Related]
12. Fatty acid metabolism as a target for obesity treatment.
Ronnett GV; Kim EK; Landree LE; Tu Y
Physiol Behav; 2005 May; 85(1):25-35. PubMed ID: 15878185
[TBL] [Abstract][Full Text] [Related]
13. The connections between C75 and obesity drug-target pathways.
Kuhajda FP; Landree LE; Ronnett GV
Trends Pharmacol Sci; 2005 Nov; 26(11):541-4. PubMed ID: 16169094
[TBL] [Abstract][Full Text] [Related]
14. C75 [4-methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylic acid] activates carnitine palmitoyltransferase-1 in isolated mitochondria and intact cells without displacement of bound malonyl CoA.
Yang N; Kays JS; Skillman TR; Burris L; Seng TW; Hammond C
J Pharmacol Exp Ther; 2005 Jan; 312(1):127-33. PubMed ID: 15356215
[TBL] [Abstract][Full Text] [Related]
15. Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase.
Wang X; Tian W
Biochem Biophys Res Commun; 2001 Nov; 288(5):1200-6. PubMed ID: 11700039
[TBL] [Abstract][Full Text] [Related]
16. Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer.
Oliveras G; Blancafort A; Urruticoechea A; Campuzano O; Gómez-Cabello D; Brugada R; López-Rodríguez ML; Colomer R; Puig T
Ann N Y Acad Sci; 2010 Oct; 1210():86-92. PubMed ID: 20973802
[TBL] [Abstract][Full Text] [Related]
17. Epigallocatechin-3 gallate induces growth inhibition and apoptosis in human breast cancer cells through survivin suppression.
Tang Y; Zhao DY; Elliott S; Zhao W; Curiel TJ; Beckman BS; Burow ME
Int J Oncol; 2007 Oct; 31(4):705-11. PubMed ID: 17786300
[TBL] [Abstract][Full Text] [Related]
18. C75 activates malonyl-CoA sensitive and insensitive components of the CPT system.
Nicot C; Napal L; Relat J; González S; Llebaria A; Woldegiorgis G; Marrero PF; Haro D
Biochem Biophys Res Commun; 2004 Dec; 325(3):660-4. PubMed ID: 15541339
[TBL] [Abstract][Full Text] [Related]
19. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity.
Thupari JN; Landree LE; Ronnett GV; Kuhajda FP
Proc Natl Acad Sci U S A; 2002 Jul; 99(14):9498-502. PubMed ID: 12060712
[TBL] [Abstract][Full Text] [Related]
20. Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.
Menendez JA; Vazquez-Martin A; Oliveras-Ferraros C; Garcia-Villalba R; Carrasco-Pancorbo A; Fernandez-Gutierrez A; Segura-Carretero A
Int J Mol Med; 2008 Oct; 22(4):433-9. PubMed ID: 18813848
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]