BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 17905589)

  • 1. Pyridazinone derivatives: design, synthesis, and in vitro vasorelaxant activity.
    Abouzid K; Abdel Hakeem M; Khalil O; Maklad Y
    Bioorg Med Chem; 2008 Jan; 16(1):382-9. PubMed ID: 17905589
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of new 4,5-3(2H)pyridazinone derivatives and their cardiotonic, hypotensive, and platelet aggregation inhibition activities.
    Amin EN; Abdel-Alim AA; Abdel-Moty SG; El-Shorbagi AN; Abdel-Rahman MSh
    Arch Pharm Res; 2010 Jan; 33(1):25-46. PubMed ID: 20191341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of 2-substituted-6-phenyl-4,5-dihydropyridazin-3(2H)-ones as potent inodilators.
    Kumar D; Carron R; La Calle CD; Jindal DP; Bansal R
    Acta Pharm; 2008 Dec; 58(4):393-405. PubMed ID: 19103574
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone.
    Bansal R; Kumar D; Carron R; de la Calle C
    Eur J Med Chem; 2009 Nov; 44(11):4441-7. PubMed ID: 19589624
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and structure-activity relationship studies of 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives as cardiotonic agents.
    Wang T; Dong Y; Wang LC; Xiang BR; Chen Z; Qu LB
    Arzneimittelforschung; 2008; 58(11):569-73. PubMed ID: 19137907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Solid-phase synthesis and evaluation of libraries of substituted 4,5-dihydropyridazinones as vasodilator agents.
    Gouault N; Martin-Chouly CA; Lugnier C; Cupif JF; Tonnelier A; Feger F; Lagente V; David M
    J Pharm Pharmacol; 2004 Aug; 56(8):1029-37. PubMed ID: 15285848
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and bioactivity of 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives.
    Wang T; Dong Y; Wang LC; Chen Z
    Arzneimittelforschung; 2007; 57(10):641-6. PubMed ID: 18074757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological activity of some 1,3-dihydro-2H-3-benzazepin-2-ones with a piperazine moiety as bradycardic agents.
    Liang HY; Zhang DQ; Yue Y; Shi Z; Zhao SY
    Arch Pharm (Weinheim); 2010 Feb; 343(2):114-9. PubMed ID: 20108265
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for the treatment of congestive heart failure.
    Sircar I; Steffen RP; Bobowski G; Burke SE; Newton RS; Weishaar RE; Bristol JA; Evans DB
    J Med Chem; 1989 Feb; 32(2):342-50. PubMed ID: 2536438
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and selective coronary vasodilatory activity of 3,4-dihydro-2,2-bis(methoxymethyl)-2H-1-benzopyran-3-ol derivatives: novel potassium channel openers.
    Cho H; Katoh S; Sayama S; Murakami K; Nakanishi H; Kajimoto Y; Ueno H; Kawasaki H; Aisaka K; Uchida I
    J Med Chem; 1996 Sep; 39(19):3797-805. PubMed ID: 8809167
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Synthesis and vasorelaxant activities of benzopyran-4-one hydrazone derivatives].
    Zhao SY; Huang WL; Zhang HB
    Yao Xue Xue Bao; 2002 Aug; 37(8):621-5. PubMed ID: 12567776
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cardiotonic agents. 3. Synthesis and biological activity of novel 6-(substituted 1H-imidazol-4(5)-yl)-3(2H)-pyridazinones.
    Sircar I; Bobowski G; Bristol JA; Weishaar RE; Evans DB
    J Med Chem; 1986 Feb; 29(2):261-7. PubMed ID: 3950907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Studies on synthesis, anticonvulsant activity and the structure--activity relationships of 6-(substituted phenyl)-3 (2H) pyridazinones].
    Xu P; Wang SY; Chen Y; Liu WQ; Tao C
    Yao Xue Xue Bao; 1991; 26(9):656-60. PubMed ID: 1821084
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Some pyrrole substituted aryl pyridazinone and phthalazinone derivatives and their antihypertensive activities.
    Demirayak S; Karaburun AC; Beis R
    Eur J Med Chem; 2004 Dec; 39(12):1089-95. PubMed ID: 15571871
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-activity relationships of cis-tetrahydrophthalazinone/pyridazinone hybrids: a novel series of potent dual PDE3/PDE4 inhibitory agents.
    Van der Mey M; Bommelé KM; Boss H; Hatzelmann A; Van Slingerland M; Sterk GJ; Timmerman H
    J Med Chem; 2003 May; 46(10):2008-16. PubMed ID: 12723963
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and positive inotropic activity of N-(4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolin-7-yl)-2-(piperazin-1-yl)acetamide derivatives.
    Zhang CB; Cui X; Hong L; Quan ZS; Piao HR
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4606-9. PubMed ID: 18657421
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies of cardiotonic agents. 8. Synthesis and biological activities of optically active 6-(4-(benzylamino)-7-quinazolinyl)-4,5-dihydro-5-methyl-3(2H)- pyridazinone (KF15232).
    Nomoto Y; Takai H; Ohno T; Nagashima K; Yao K; Yamada K; Kubo K; Ichimura M; Mihara A; Kase H
    J Med Chem; 1996 Jan; 39(1):297-303. PubMed ID: 8568820
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, Molecular Modeling of Novel Substituted Pyridazinones and their Vasorelaxant Activities.
    Ismail MMF; Soliman DHS; Elmoniem MHA; Jaleel GAA
    Med Chem; 2021; 17(2):171-186. PubMed ID: 32216740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of 2-(4-substitutedmethylpiperazin-1-yl)-N-(3,4-dihydro-3-oxo-2H-benzo[b][1,4]oxazin-7-yl)acetamides and their positive inotropic evaluation.
    Liu XK; Cui X; Hong L; Sun LP; Quan ZS; Piao HR
    Eur J Med Chem; 2009 Jul; 44(7):3027-31. PubMed ID: 18824278
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors.
    Zhou G; Ting PC; Aslanian R; Cao J; Kim DW; Kuang R; Lee JF; Schwerdt J; Wu H; Herr RJ; Zych AJ; Yang J; Lam S; Wainhaus S; Black TA; McNicholas PM; Xu Y; Walker SS
    Bioorg Med Chem Lett; 2011 May; 21(10):2890-3. PubMed ID: 21489787
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.