These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
298 related articles for article (PubMed ID: 17907768)
1. Advanced pharmacokinetic models based on organ clearance, circulatory, and fractal concepts. Pang KS; Weiss M; Macheras P AAPS J; 2007 Jun; 9(2):E268-83. PubMed ID: 17907768 [TBL] [Abstract][Full Text] [Related]
2. Utility of a single adjusting compartment: a novel methodology for whole body physiologically-based pharmacokinetic modelling. Ando H; Izawa S; Hori W; Nakagawa I Theor Biol Med Model; 2008 Aug; 5():19. PubMed ID: 18687151 [TBL] [Abstract][Full Text] [Related]
3. Physiologically based approaches towards the prediction of pharmacokinetics: in vitro-in vivo extrapolation. De Buck SS; Mackie CE Expert Opin Drug Metab Toxicol; 2007 Dec; 3(6):865-78. PubMed ID: 18028030 [TBL] [Abstract][Full Text] [Related]
4. A valid equation for the well-stirred perfusion limited physiologically based pharmacokinetic model that consistently accounts for the blood-tissue drug distribution in the organ and the corresponding valid equation for the steady state volume of distribution. Berezhkovskiy LM J Pharm Sci; 2010 Jan; 99(1):475-85. PubMed ID: 19492340 [TBL] [Abstract][Full Text] [Related]
5. On the accuracy of estimation of basic pharmacokinetic parameters by the traditional noncompartmental equations and the prediction of the steady-state volume of distribution in obese patients based upon data derived from normal subjects. Berezhkovskiy LM J Pharm Sci; 2011 Jun; 100(6):2482-97. PubMed ID: 21254063 [TBL] [Abstract][Full Text] [Related]
6. Application of hybrid approach based on empirical and physiological concept for predicting pharmacokinetics in humans--usefulness of exponent on prospective evaluation of predictability. Sayama H; Komura H; Kogayu M Drug Metab Dispos; 2013 Feb; 41(2):498-507. PubMed ID: 23209193 [TBL] [Abstract][Full Text] [Related]
7. PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: prediction of plasma concentration-time profiles in human by using the physiologically-based pharmacokinetic modeling approach. Poulin P; Jones RD; Jones HM; Gibson CR; Rowland M; Chien JY; Ring BJ; Adkison KK; Ku MS; He H; Vuppugalla R; Marathe P; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Yates JW J Pharm Sci; 2011 Oct; 100(10):4127-57. PubMed ID: 21541937 [TBL] [Abstract][Full Text] [Related]
8. Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved. Li R; Barton HA; Varma MV Clin Pharmacokinet; 2014 Aug; 53(8):659-78. PubMed ID: 25056496 [TBL] [Abstract][Full Text] [Related]
9. Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds. Li R; Maurer TS; Sweeney K; Barton HA AAPS J; 2016 May; 18(3):746-56. PubMed ID: 26951483 [TBL] [Abstract][Full Text] [Related]
10. Moments of physiological transit time distributions and the time course of drug disposition in the body. Weiss M J Math Biol; 1982; 15(3):305-18. PubMed ID: 7153675 [TBL] [Abstract][Full Text] [Related]
11. A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding. Ye M; Nagar S; Korzekwa K Biopharm Drug Dispos; 2016 Apr; 37(3):123-41. PubMed ID: 26531057 [TBL] [Abstract][Full Text] [Related]
12. Conceptual underestimation of the total body clearance by the sum of clearances of individual organs in physiologically based pharmacokinetics. Berezhkovskiy LM J Pharm Sci; 2012 Dec; 101(12):4660-5. PubMed ID: 23001916 [TBL] [Abstract][Full Text] [Related]
13. Steady-state distribution volume in physiologic multi-organ systems. Weiss M Biopharm Drug Dispos; 1983; 4(2):151-6. PubMed ID: 6882883 [TBL] [Abstract][Full Text] [Related]
14. Profiling of Drug-Metabolizing Enzymes and Transporters in Human Tissue Biopsy Samples: A Review of the Literature. Rodrigues AD; Rowland A J Pharmacol Exp Ther; 2020 Mar; 372(3):308-319. PubMed ID: 31879375 [TBL] [Abstract][Full Text] [Related]
15. Dose selection based on physiologically based pharmacokinetic (PBPK) approaches. Jones HM; Mayawala K; Poulin P AAPS J; 2013 Apr; 15(2):377-87. PubMed ID: 23269526 [TBL] [Abstract][Full Text] [Related]
16. Successful Prediction of Human Pharmacokinetics by Improving Calculation Processes of Physiologically Based Pharmacokinetic Approach. Mayumi K; Ohnishi S; Hasegawa H J Pharm Sci; 2019 Aug; 108(8):2718-2727. PubMed ID: 30876861 [TBL] [Abstract][Full Text] [Related]
17. Prediction of total hepatic clearance by combining metabolism, transport, and permeability data in the in vitro-in vivo extrapolation methods: emphasis on an apparent fraction unbound in liver for drugs. Poulin P J Pharm Sci; 2013 Jul; 102(7):2085-95. PubMed ID: 23613473 [TBL] [Abstract][Full Text] [Related]
18. Towards human Stevens LJ; Donkers JM; Dubbeld J; Vaes WHJ; Knibbe CAJ; Alwayn IPJ; van de Steeg E Drug Metab Rev; 2020 Aug; 52(3):438-454. PubMed ID: 32551945 [TBL] [Abstract][Full Text] [Related]
19. Application of a physiologically based pharmacokinetic model informed by a top-down approach for the prediction of pharmacokinetics in chronic kidney disease patients. Sayama H; Takubo H; Komura H; Kogayu M; Iwaki M AAPS J; 2014 Sep; 16(5):1018-28. PubMed ID: 24912798 [TBL] [Abstract][Full Text] [Related]
20. On the Nature of Physiologically-Based Pharmacokinetic Models -A Priori or A Posteriori? Mechanistic or Empirical? Korzekwa K; Nagar S Pharm Res; 2017 Mar; 34(3):529-534. PubMed ID: 28028770 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]