BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 17909812)

  • 1. Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice.
    Haklai R; Elad-Sfadia G; Egozi Y; Kloog Y
    Cancer Chemother Pharmacol; 2008 Jan; 61(1):89-96. PubMed ID: 17909812
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer.
    Laheru D; Shah P; Rajeshkumar NV; McAllister F; Taylor G; Goldsweig H; Le DT; Donehower R; Jimeno A; Linden S; Zhao M; Song D; Rudek MA; Hidalgo M
    Invest New Drugs; 2012 Dec; 30(6):2391-9. PubMed ID: 22547163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Salirasib in the treatment of pancreatic cancer.
    Bustinza-Linares E; Kurzrock R; Tsimberidou AM
    Future Oncol; 2010 Jun; 6(6):885-91. PubMed ID: 20528225
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry.
    Zhao M; He P; Xu L; Hidalgo M; Laheru D; Rudek MA
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Jun; 869(1-2):142-5. PubMed ID: 18534927
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance.
    Gana-Weisz M; Halaschek-Wiener J; Jansen B; Elad G; Haklai R; Kloog Y
    Clin Cancer Res; 2002 Feb; 8(2):555-65. PubMed ID: 11839677
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An early clinical trial of Salirasib, an oral RAS inhibitor, in Japanese patients with relapsed/refractory solid tumors.
    Furuse J; Kurata T; Okano N; Fujisaka Y; Naruge D; Shimizu T; Kitamura H; Iwasa T; Nagashima F; Nakagawa K
    Cancer Chemother Pharmacol; 2018 Sep; 82(3):511-519. PubMed ID: 29992354
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice.
    Weisz B; Giehl K; Gana-Weisz M; Egozi Y; Ben-Baruch G; Marciano D; Gierschik P; Kloog Y
    Oncogene; 1999 Apr; 18(16):2579-88. PubMed ID: 10353601
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models.
    Goldberg L; Haklai R; Bauer V; Heiss A; Kloog Y
    J Med Chem; 2009 Jan; 52(1):197-205. PubMed ID: 19072665
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid).
    Zundelevich A; Elad-Sfadia G; Haklai R; Kloog Y
    Mol Cancer Ther; 2007 Jun; 6(6):1765-73. PubMed ID: 17541036
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FTS and 2-DG induce pancreatic cancer cell death and tumor shrinkage in mice.
    Goldberg L; Israeli R; Kloog Y
    Cell Death Dis; 2012 Mar; 3(3):e284. PubMed ID: 22419113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib.
    Faigenbaum R; Haklai R; Ben-Baruch G; Kloog Y
    Oncotarget; 2013 Feb; 4(2):316-28. PubMed ID: 23530112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer.
    Rotblat B; Ehrlich M; Haklai R; Kloog Y
    Methods Enzymol; 2008; 439():467-89. PubMed ID: 18374183
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase I study of S-trans, trans-farnesylthiosalicylic acid (salirasib), a novel oral RAS inhibitor in patients with refractory hematologic malignancies.
    Badar T; Cortes JE; Ravandi F; O'Brien S; Verstovsek S; Garcia-Manero G; Kantarjian H; Borthakur G
    Clin Lymphoma Myeloma Leuk; 2015 Jul; 15(7):433-438.e2. PubMed ID: 25795639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Ras-pathway inhibitor, S-trans-trans-farnesylthiosalicylic acid, suppresses experimental allergic encephalomyelitis.
    Karussis D; Abramsky O; Grigoriadis N; Chapman J; Mizrachi-Koll R; Niv H; Kloog Y
    J Neuroimmunol; 2001 Nov; 120(1-2):1-9. PubMed ID: 11694313
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells.
    Santen RJ; Lynch AR; Neal LR; McPherson RA; Yue W
    Anticancer Drugs; 2006 Jan; 17(1):33-40. PubMed ID: 16317288
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ras inhibition by FTS attenuates brain tumor growth in mice by direct antitumor activity and enhanced reactivity of cytotoxic lymphocytes.
    Aizman E; Mor A; Levy A; George J; Kloog Y
    Oncotarget; 2012 Feb; 3(2):144-57. PubMed ID: 22323550
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhancing FTS (Salirasib) efficiency via combinatorial treatment.
    Wolfson E; Schmukler E; Schokoroy ST; Kloog Y; Pinkas-Kramarski R
    Biol Cell; 2015 May; 107(5):130-43. PubMed ID: 25735913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition.
    Charette N; De Saeger C; Lannoy V; Horsmans Y; Leclercq I; Stärkel P
    Mol Cancer; 2010 Sep; 9():256. PubMed ID: 20860815
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats.
    Reif S; Weis B; Aeed H; Gana-Weis M; Zaidel L; Avni Y; Romanelli RG; Pinzani M; Kloog Y; Bruck R
    J Hepatol; 1999 Dec; 31(6):1053-61. PubMed ID: 10604579
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ras chaperones: new targets for cancer and immunotherapy.
    Kloog Y; Elad-Sfadia G; Haklai R; Mor A
    Enzymes; 2013; 33 Pt A():267-89. PubMed ID: 25033809
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.