BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 17913796)

  • 1. Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice.
    Tian X; Zamek-Gliszczynski MJ; Li J; Bridges AS; Nezasa K; Patel NJ; Raub TJ; Brouwer KL
    Drug Metab Dispos; 2008 Jan; 36(1):61-4. PubMed ID: 17913796
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1.
    Zamek-Gliszczynski MJ; Hoffmaster KA; Tian X; Zhao R; Polli JW; Humphreys JE; Webster LO; Bridges AS; Kalvass JC; Brouwer KL
    Drug Metab Dispos; 2005 Aug; 33(8):1158-65. PubMed ID: 15860656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles of P-glycoprotein, Bcrp, and Mrp2 in biliary excretion of spiramycin in mice.
    Tian X; Li J; Zamek-Gliszczynski MJ; Bridges AS; Zhang P; Patel NJ; Raub TJ; Pollack GM; Brouwer KL
    Antimicrob Agents Chemother; 2007 Sep; 51(9):3230-4. PubMed ID: 17576841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.
    Matsushima S; Maeda K; Hayashi H; Debori Y; Schinkel AH; Schuetz JD; Kusuhara H; Sugiyama Y
    Mol Pharmacol; 2008 May; 73(5):1474-83. PubMed ID: 18245269
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in biliary excretion of 4-methylumbelliferyl glucuronide and sulfate in the rat.
    Zamek-Gliszczynski MJ; Hoffmaster KA; Humphreys JE; Tian X; Nezasa K; Brouwer KL
    J Pharmacol Exp Ther; 2006 Oct; 319(1):459-67. PubMed ID: 16857726
    [TBL] [Abstract][Full Text] [Related]  

  • 6. P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.
    Tahara H; Kusuhara H; Fuse E; Sugiyama Y
    Drug Metab Dispos; 2005 Jul; 33(7):963-8. PubMed ID: 15821041
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatobiliary disposition of the metabolically stable opioid peptide [D-Pen2, D-Pen5]-enkephalin (DPDPE): pharmacokinetic consequences of the interplay between multiple transport systems.
    Hoffmaster KA; Zamek-Gliszczynski MJ; Pollack GM; Brouwer KL
    J Pharmacol Exp Ther; 2004 Dec; 311(3):1203-10. PubMed ID: 15302892
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver.
    Ahmed S; Vo NT; Thalhammer T; Thalhammer F; Gattringer KB; Jäger W
    J Pharm Pharmacol; 2008 Jan; 60(1):55-62. PubMed ID: 18088505
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.
    Tian X; Swift B; Zamek-Gliszczynski MJ; Belinsky MG; Kruh GD; Brouwer KL
    Drug Metab Dispos; 2008 May; 36(5):911-5. PubMed ID: 18276836
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatobiliary disposition of 3alpha,6alpha,7alpha,12alpha-tetrahydroxy-cholanoyl taurine: a substrate for multiple canalicular transporters.
    Megaraj V; Iida T; Jungsuwadee P; Hofmann AF; Vore M
    Drug Metab Dispos; 2010 Oct; 38(10):1723-30. PubMed ID: 20643783
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apparent differences in mechanisms of harmol sulfate biliary excretion in mice and rats.
    Zamek-Gliszczynski MJ; Hoffmaster KA; Nezasa K; Brouwer KL
    Drug Metab Dispos; 2008 Nov; 36(11):2156-8. PubMed ID: 18719241
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment.
    Xiong H; Suzuki H; Sugiyama Y; Meier PJ; Pollack GM; Brouwer KL
    Drug Metab Dispos; 2002 Sep; 30(9):962-9. PubMed ID: 12167560
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats.
    Xiong H; Turner KC; Ward ES; Jansen PL; Brouwer KL
    J Pharmacol Exp Ther; 2000 Nov; 295(2):512-8. PubMed ID: 11046083
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism and disposition of resveratrol in the isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides.
    Maier-Salamon A; Hagenauer B; Reznicek G; Szekeres T; Thalhammer T; Jäger W
    J Pharm Sci; 2008 Apr; 97(4):1615-28. PubMed ID: 17724663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Decreased hepatic breast cancer resistance protein expression and function in multidrug resistance-associated protein 2-deficient (TR⁻) rats.
    Yue W; Lee JK; Abe K; Sugiyama Y; Brouwer KL
    Drug Metab Dispos; 2011 Mar; 39(3):441-7. PubMed ID: 21106720
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.
    Swift B; Tian X; Brouwer KL
    Pharm Res; 2009 Aug; 26(8):1942-51. PubMed ID: 19495943
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2).
    Miranda SR; Lee JK; Brouwer KL; Wen Z; Smith PC; Hawke RL
    Drug Metab Dispos; 2008 Nov; 36(11):2219-26. PubMed ID: 18687803
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
    Dahan A; Sabit H; Amidon GL
    Drug Metab Dispos; 2009 Oct; 37(10):2028-36. PubMed ID: 19589874
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2).
    Chu XY; Strauss JR; Mariano MA; Li J; Newton DJ; Cai X; Wang RW; Yabut J; Hartley DP; Evans DC; Evers R
    J Pharmacol Exp Ther; 2006 May; 317(2):579-89. PubMed ID: 16421286
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice.
    Nezasa K; Tian X; Zamek-Gliszczynski MJ; Patel NJ; Raub TJ; Brouwer KL
    Drug Metab Dispos; 2006 Apr; 34(4):718-23. PubMed ID: 16434545
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.