199 related articles for article (PubMed ID: 17916066)
1. Validation of spermidine synthase as a drug target in African trypanosomes.
Taylor MC; Kaur H; Blessington B; Kelly JM; Wilkinson SR
Biochem J; 2008 Jan; 409(2):563-9. PubMed ID: 17916066
[TBL] [Abstract][Full Text] [Related]
2. RNA interference-mediated silencing of ornithine decarboxylase and spermidine synthase genes in Trypanosoma brucei provides insight into regulation of polyamine biosynthesis.
Xiao Y; McCloskey DE; Phillips MA
Eukaryot Cell; 2009 May; 8(5):747-55. PubMed ID: 19304951
[TBL] [Abstract][Full Text] [Related]
3. Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis.
Heby O; Persson L; Rentala M
Amino Acids; 2007 Aug; 33(2):359-66. PubMed ID: 17610127
[TBL] [Abstract][Full Text] [Related]
4. In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei.
Fairlamb AH; Henderson GB; Bacchi CJ; Cerami A
Mol Biochem Parasitol; 1987 Jun; 24(2):185-91. PubMed ID: 3114634
[TBL] [Abstract][Full Text] [Related]
5. Trypanosoma brucei brucei: characterization of an ODC null bloodstream form mutant and the action of alpha-difluoromethylornithine.
Li F; Hua SB; Wang CC; Gottesdiener KM
Exp Parasitol; 1998 Mar; 88(3):255-7. PubMed ID: 9562432
[TBL] [Abstract][Full Text] [Related]
6. Antitrypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-L-methionine.
Byers TL; Bush TL; McCann PP; Bitonti AJ
Biochem J; 1991 Mar; 274 ( Pt 2)(Pt 2):527-33. PubMed ID: 1672500
[TBL] [Abstract][Full Text] [Related]
7. In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei.
Bacchi CJ; Garofalo J; Mockenhaupt D; McCann PP; Diekema KA; Pegg AE; Nathan HC; Mullaney EA; Chunosoff L; Sjoerdsma A; Hutner SH
Mol Biochem Parasitol; 1983 Mar; 7(3):209-25. PubMed ID: 6193423
[TBL] [Abstract][Full Text] [Related]
8. [DFMO: an alternative therapeutic agent for human African trypanosomiasis].
Breton JC; Bouteille B; Sonan T
Bull Soc Pathol Exot Filiales; 1988; 81(3 Pt 2):571-7. PubMed ID: 3143490
[TBL] [Abstract][Full Text] [Related]
9. Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model.
Dauchy FA; Bonhivers M; Landrein N; Dacheux D; Courtois P; Lauruol F; Daulouède S; Vincendeau P; Robinson DR
PLoS Negl Trop Dis; 2016 Nov; 10(11):e0005125. PubMed ID: 27855164
[TBL] [Abstract][Full Text] [Related]
10. Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralog.
Nguyen S; Jones DC; Wyllie S; Fairlamb AH; Phillips MA
J Biol Chem; 2013 May; 288(21):15256-67. PubMed ID: 23525104
[TBL] [Abstract][Full Text] [Related]
11. Regulation and function of polyamines in African trypanosomes.
Willert E; Phillips MA
Trends Parasitol; 2012 Feb; 28(2):66-72. PubMed ID: 22192816
[TBL] [Abstract][Full Text] [Related]
12. In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors.
Bacchi CJ; Brun R; Croft SL; Alicea K; Bühler Y
Antimicrob Agents Chemother; 1996 Jun; 40(6):1448-53. PubMed ID: 8726018
[TBL] [Abstract][Full Text] [Related]
13. Effects of polyamines on two strains of Trypanosoma brucei in infected rats and in vitro culture.
Nishimura K; Yanase T; Araki N; Ohnishi Y; Kozaki S; Shima K; Asakura M; Samosomsuk W; Yamasaki S
J Parasitol; 2006 Apr; 92(2):211-7. PubMed ID: 16729674
[TBL] [Abstract][Full Text] [Related]
14. Spermidine is essential for normal proliferation of trypanosomatid protozoa.
González NS; Huber A; Algranati ID
FEBS Lett; 2001 Nov; 508(3):323-6. PubMed ID: 11728444
[TBL] [Abstract][Full Text] [Related]
15. Characterization of spermidine synthase from Trypanosoma brucei brucei.
Bitonti AJ; Kelly SE; McCann PP
Mol Biochem Parasitol; 1984 Sep; 13(1):21-8. PubMed ID: 6513985
[TBL] [Abstract][Full Text] [Related]
16. Polyamine metabolism: a potential therapeutic target in trypanosomes.
Bacchi CJ; Nathan HC; Hutner SH; McCann PP; Sjoerdsma A
Science; 1980 Oct; 210(4467):332-4. PubMed ID: 6775372
[TBL] [Abstract][Full Text] [Related]
17. A novel suicide inhibitor strategy for antiparasitic drug development.
Wang CC
J Cell Biochem; 1991 Jan; 45(1):49-53. PubMed ID: 2005184
[TBL] [Abstract][Full Text] [Related]
18. Physiological activation of the mitochondrion and the transformation capacity of DFMO induced intermediate and short stumpy bloodstream form trypanosomes.
Giffin BF; McCann PP
Am J Trop Med Hyg; 1989 May; 40(5):487-93. PubMed ID: 2499202
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of DL-alpha-difluoromethylornithine against susceptible and drug-resistant Trypanosoma brucei brucei.
Zweygarth E; Kaminsky R
Acta Trop; 1991 Jan; 48(3):223-32. PubMed ID: 1671624
[TBL] [Abstract][Full Text] [Related]
20. Further studies on difluoromethylornithine in African trypanosomes.
McCann PP; Bacchi CJ; Clarkson AB; Seed JR; Nathan HC; Amole BO; Hutner SH; Sjoerdsma A
Med Biol; 1981 Dec; 59(5-6):434-40. PubMed ID: 6175860
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
