BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 17920282)

  • 1. Discovery of novel alpha-glucosidase inhibitors based on the virtual screening with the homology-modeled protein structure.
    Park H; Hwang KY; Oh KH; Kim YH; Lee JY; Kim K
    Bioorg Med Chem; 2008 Jan; 16(1):284-92. PubMed ID: 17920282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-based virtual screening approach to identify novel classes of PTP1B inhibitors.
    Park H; Bhattarai BR; Ham SW; Cho H
    Eur J Med Chem; 2009 Aug; 44(8):3280-4. PubMed ID: 19269068
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery and biological evaluation of novel alpha-glucosidase inhibitors with in vivo antidiabetic effect.
    Park H; Hwang KY; Kim YH; Oh KH; Lee JY; Kim K
    Bioorg Med Chem Lett; 2008 Jul; 18(13):3711-5. PubMed ID: 18524587
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel PRL-3 inhibitors based on the structure-based virtual screening.
    Park H; Jung SK; Jeong DG; Ryu SE; Kim SJ
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2250-5. PubMed ID: 18358718
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitors.
    Park H; Li M; Choi J; Cho H; Ham SW
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4372-5. PubMed ID: 19500977
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening.
    Park H; Bahn YJ; Jung SK; Jeong DG; Lee SH; Seo I; Yoon TS; Kim SJ; Ryu SE
    J Med Chem; 2008 Sep; 51(18):5533-41. PubMed ID: 18714978
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of novel inhibitors of extracellular signal-regulated kinase 2 based on the structure-based virtual screening.
    Park H; Bahn YJ; Jeong DG; Woo EJ; Kwon JS; Ryu SE
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5372-6. PubMed ID: 18835158
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Binding mode analyses and pharmacophore model development for sulfonamide chalcone derivatives, a new class of alpha-glucosidase inhibitors.
    Bharatham K; Bharatham N; Park KH; Lee KW
    J Mol Graph Model; 2008 Jun; 26(8):1202-12. PubMed ID: 18096420
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based virtual screening approach to the discovery of phosphoinositide 3-kinase alpha inhibitors.
    Park H; Choi H; Hong S; Kim D; Oh DS; Hong S
    Bioorg Med Chem Lett; 2011 Apr; 21(7):2021-4. PubMed ID: 21354792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure.
    Park H; Chi O; Kim J; Hong S
    J Chem Inf Model; 2011 Nov; 51(11):2986-93. PubMed ID: 22017333
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based virtual screening approach to the discovery of novel inhibitors of factor-inhibiting HIF-1: identification of new chelating groups for the active-site ferrous ion.
    Ko S; Lee MK; Shin D; Park H
    Bioorg Med Chem; 2009 Nov; 17(22):7769-74. PubMed ID: 19822432
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure modeling, ligand binding, and binding affinity calculation (LR-MM-PBSA) of human heparanase for inhibition and drug design.
    Zhou Z; Bates M; Madura JD
    Proteins; 2006 Nov; 65(3):580-92. PubMed ID: 16972282
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Homology modeling and virtual screening approaches to identify potent inhibitors of slingshot phosphatase 1.
    Park H; Park SY; Ryu SE
    J Mol Graph Model; 2013 Feb; 39():65-70. PubMed ID: 23220283
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening.
    Park H; Chien PN; Ryu SE
    Bioorg Med Chem Lett; 2012 Oct; 22(20):6333-7. PubMed ID: 22989533
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based virtual screening approach to the discovery of novel PTPMT1 phosphatase inhibitors.
    Park H; Kim SY; Kyung A; Yoon TS; Ryu SE; Jeong DG
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1271-5. PubMed ID: 22115589
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Importance of molecular computer modeling in anticancer drug development.
    Geromichalos GD
    J BUON; 2007 Sep; 12 Suppl 1():S101-18. PubMed ID: 17935268
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based virtual screening approach to the discovery of novel inhibitors of eyes absent 2 phosphatase with various metal chelating moieties.
    Park H; Jung SK; Yu KR; Kim JH; Kim YS; Ko JH; Park BC; Kim SJ
    Chem Biol Drug Des; 2011 Oct; 78(4):642-50. PubMed ID: 21777393
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and evaluation of the alpha-glucosidase inhibitory activity of 3-[4-(phenylsulfonamido)benzoyl]-2H-1-benzopyran-2-one derivatives.
    Wang S; Yan J; Wang X; Yang Z; Lin F; Zhang T
    Eur J Med Chem; 2010 Mar; 45(3):1250-5. PubMed ID: 20045223
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of the inhibitors of tumor necrosis factor alpha with structure-based virtual screening.
    Choi H; Lee Y; Park H; Oh DS
    Bioorg Med Chem Lett; 2010 Nov; 20(21):6195-8. PubMed ID: 20850306
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based virtual screening approach to the discovery of p38 MAP kinase inhibitors.
    Choi H; Park HJ; Shin JC; Ko HS; Lee JK; Lee S; Park H; Hong S
    Bioorg Med Chem Lett; 2012 Mar; 22(6):2195-9. PubMed ID: 22342625
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.