193 related articles for article (PubMed ID: 17920628)
1. Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor.
Trible RP; Emert-Sedlak L; Wales TE; Ayyavoo V; Engen JR; Smithgall TE
J Mol Biol; 2007 Nov; 374(1):121-9. PubMed ID: 17920628
[TBL] [Abstract][Full Text] [Related]
2. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
Alvarado JJ; Tarafdar S; Yeh JI; Smithgall TE
J Biol Chem; 2014 Oct; 289(41):28539-53. PubMed ID: 25122770
[TBL] [Abstract][Full Text] [Related]
3. Conserved residues in the HIV-1 Nef hydrophobic pocket are essential for recruitment and activation of the Hck tyrosine kinase.
Choi HJ; Smithgall TE
J Mol Biol; 2004 Nov; 343(5):1255-68. PubMed ID: 15491611
[TBL] [Abstract][Full Text] [Related]
4. Oligomerization is required for HIV-1 Nef-induced activation of the Src family protein-tyrosine kinase, Hck.
Ye H; Choi HJ; Poe J; Smithgall TE
Biochemistry; 2004 Dec; 43(50):15775-84. PubMed ID: 15595833
[TBL] [Abstract][Full Text] [Related]
5. Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.
Narute PS; Smithgall TE
PLoS One; 2012; 7(2):e32561. PubMed ID: 22393415
[TBL] [Abstract][Full Text] [Related]
6. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein.
Lee CH; Leung B; Lemmon MA; Zheng J; Cowburn D; Kuriyan J; Saksela K
EMBO J; 1995 Oct; 14(20):5006-15. PubMed ID: 7588629
[TBL] [Abstract][Full Text] [Related]
7. Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor.
Wales TE; Hochrein JM; Morgan CR; Emert-Sedlak LA; Smithgall TE; Engen JR
Biochemistry; 2015 Oct; 54(41):6382-91. PubMed ID: 26440750
[TBL] [Abstract][Full Text] [Related]
8. SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.
Briggs SD; Sharkey M; Stevenson M; Smithgall TE
J Biol Chem; 1997 Jul; 272(29):17899-902. PubMed ID: 9218412
[TBL] [Abstract][Full Text] [Related]
9. SH3 domains with high affinity and engineered ligand specificities targeted to HIV-1 Nef.
Hiipakka M; Poikonen K; Saksela K
J Mol Biol; 1999 Nov; 293(5):1097-106. PubMed ID: 10547288
[TBL] [Abstract][Full Text] [Related]
10. HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon.
Cornall A; Mak J; Greenway A; Tachedjian G
Viruses; 2013 Sep; 5(9):2235-52. PubMed ID: 24051604
[TBL] [Abstract][Full Text] [Related]
11. Structure, dynamics, and Hck interaction of full-length HIV-1 Nef.
Jung J; Byeon IJ; Ahn J; Gronenborn AM
Proteins; 2011 May; 79(5):1609-22. PubMed ID: 21365684
[TBL] [Abstract][Full Text] [Related]
12. Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.
Greenway AL; Dutartre H; Allen K; McPhee DA; Olive D; Collette Y
J Virol; 1999 Jul; 73(7):6152-8. PubMed ID: 10364375
[TBL] [Abstract][Full Text] [Related]
13. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
Dutartre H; Harris M; Olive D; Collette Y
Virology; 1998 Aug; 247(2):200-11. PubMed ID: 9705913
[TBL] [Abstract][Full Text] [Related]
14. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
Moarefi I; LaFevre-Bernt M; Sicheri F; Huse M; Lee CH; Kuriyan J; Miller WT
Nature; 1997 Feb; 385(6617):650-3. PubMed ID: 9024665
[TBL] [Abstract][Full Text] [Related]
15. Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage.
Zhao Z; Fagerlund R; Tossavainen H; Hopfensperger K; Lotke R; Srinivasachar Badarinarayan S; Kirchhoff F; Permi P; Sato K; Sauter D; Saksela K
PLoS Pathog; 2021 Nov; 17(11):e1009728. PubMed ID: 34780577
[TBL] [Abstract][Full Text] [Related]
16. HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction.
Trible RP; Emert-Sedlak L; Smithgall TE
J Biol Chem; 2006 Sep; 281(37):27029-38. PubMed ID: 16849330
[TBL] [Abstract][Full Text] [Related]
17. HIV-1 Nef Induces Hck/Lyn-Dependent Expansion of Myeloid-Derived Suppressor Cells Associated with Elevated Interleukin-17/G-CSF Levels.
Priceputu E; Cool M; Bouchard N; Caceres-Cortes JR; Lowell CA; Hanna Z; Jolicoeur P
J Virol; 2021 Aug; 95(17):e0047121. PubMed ID: 34106001
[TBL] [Abstract][Full Text] [Related]
18. Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions.
Bouchet J; Hérate C; Guenzel CA; Vérollet C; Järviluoma A; Mazzolini J; Rafie S; Chames P; Baty D; Saksela K; Niedergang F; Maridonneau-Parini I; Benichou S
J Virol; 2012 May; 86(9):4856-67. PubMed ID: 22345475
[TBL] [Abstract][Full Text] [Related]
19. Interaction between Hck and HIV-1 Nef negatively regulates cell surface expression of M-CSF receptor.
Hiyoshi M; Suzu S; Yoshidomi Y; Hassan R; Harada H; Sakashita N; Akari H; Motoyoshi K; Okada S
Blood; 2008 Jan; 111(1):243-50. PubMed ID: 17893228
[TBL] [Abstract][Full Text] [Related]
20. Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.
Briggs SD; Lerner EC; Smithgall TE
Biochemistry; 2000 Jan; 39(3):489-95. PubMed ID: 10642173
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]