These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 17921698)

  • 1. Activation of polyamine catabolism by N1, N11-diethylnorspermine alters the cellular localization of mTOR and downregulates mTOR protein level in glioblastoma cells.
    Jiang R; Choi W; Hu L; Gerner EW; Hamilton SR; Zhang W
    Cancer Biol Ther; 2007 Oct; 6(10):1644-8. PubMed ID: 17921698
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma.
    Tian Y; Wang S; Wang B; Zhang J; Jiang R; Zhang W
    Oncol Rep; 2012 Apr; 27(4):1227-32. PubMed ID: 22179681
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma.
    Jiang R; Choi W; Khan A; Hess K; Gerner EW; Casero RA; Yung WK; Hamilton SR; Zhang W
    Int J Oncol; 2007 Aug; 31(2):431-40. PubMed ID: 17611701
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines.
    Stanic' I; Facchini A; Borzì RM; Stefanelli C; Flamigni F
    J Cell Physiol; 2009 Apr; 219(1):109-16. PubMed ID: 19097065
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.
    Choi W; Gerner EW; Ramdas L; Dupart J; Carew J; Proctor L; Huang P; Zhang W; Hamilton SR
    J Biol Chem; 2005 Feb; 280(5):3295-304. PubMed ID: 15546879
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells.
    Chen Y; Kramer DL; Li F; Porter CW
    Oncogene; 2003 Aug; 22(32):4964-72. PubMed ID: 12902979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase.
    Hector S; Porter CW; Kramer DL; Clark K; Prey J; Kisiel N; Diegelman P; Chen Y; Pendyala L
    Mol Cancer Ther; 2004 Jul; 3(7):813-22. PubMed ID: 15252142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.
    Tummala R; Diegelman P; Hector S; Kramer DL; Clark K; Zagst P; Fetterly G; Porter CW; Pendyala L
    Cancer Chemother Pharmacol; 2011 Feb; 67(2):401-14. PubMed ID: 20443003
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion.
    Bernacki RJ; Oberman EJ; Seweryniak KE; Atwood A; Bergeron RJ; Porter CW
    Clin Cancer Res; 1995 Aug; 1(8):847-57. PubMed ID: 9816054
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes.
    Stanic I; Cetrullo S; Facchini A; Stefanelli C; Borzì RM; Tantini B; Guarnieri C; Caldarera CM; Flamigni F
    J Cell Physiol; 2008 Jul; 216(1):153-61. PubMed ID: 18231987
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Collateral sensitivity of human melanoma multidrug-resistant variants to the polyamine analogue, N1,N11-diethylnorspermine.
    Porter CW; Ganis B; Rustum Y; Wrzosek C; Kramer DL; Bergeron RJ
    Cancer Res; 1994 Nov; 54(22):5917-24. PubMed ID: 7954423
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DENSpm overcame Bcl-2 mediated resistance against Paclitaxel treatment in MCF-7 breast cancer cells via activating polyamine catabolic machinery.
    Akyol Z; Çoker-Gürkan A; Arisan ED; Obakan-Yerlikaya P; Palavan-Ünsal N
    Biomed Pharmacother; 2016 Dec; 84():2029-2041. PubMed ID: 27881234
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
    Hector S; Tummala R; Kisiel ND; Diegelman P; Vujcic S; Clark K; Fakih M; Kramer DL; Porter CW; Pendyala L
    Cancer Chemother Pharmacol; 2008 Aug; 62(3):517-27. PubMed ID: 17987291
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apoptosis induced by the potential chemotherapeutic drug N1, N11-Diethylnorspermine in a neuroblastoma cell line.
    Söderstjerna E; Holst CM; Alm K; Oredsson SM
    Anticancer Drugs; 2010 Nov; 21(10):917-26. PubMed ID: 20729713
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells.
    Chen Y; Alm K; Vujcic S; Kramer DL; Kee K; Diegelman P; Porter CW
    Cancer Res; 2003 Jul; 63(13):3619-25. PubMed ID: 12839950
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular mechanisms underlying N1, N11-diethylnorspermine-induced apoptosis in a human breast cancer cell line.
    Holst CM; Staaf J; Jönsson G; Hegardt C; Oredsson SM
    Anticancer Drugs; 2008 Oct; 19(9):871-83. PubMed ID: 18766001
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Concentration-dependent effects of N1, N11-diethylnorspermine on melanoma cell proliferation.
    Minchin RF; Knight S; Arulpragasam A; Fogel-Petrovic M
    Int J Cancer; 2006 Jan; 118(2):509-12. PubMed ID: 16052528
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP-48664.
    Kramer DL; Black JD; Mett H; Bergeron RJ; Porter CW
    Cancer Res; 1998 Sep; 58(17):3883-90. PubMed ID: 9731498
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
    Alhonen L; Pietilä M; Halmekytö M; Kramer DL; Jänne J; Porter CW
    Mol Pharmacol; 1999 Apr; 55(4):693-8. PubMed ID: 10101027
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discordant Effects of Polyamine Depletion by DENSpm and DFMO on β-cell Cytokine Stress and Diabetes Outcomes in Mice.
    Hammoud B; Nelson JB; May SC; Tersey SA; Mirmira RG
    Endocrinology; 2024 Jan; 165(3):. PubMed ID: 38195178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.