BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1145 related articles for article (PubMed ID: 17923681)

  • 1. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
    Lombard DB; Alt FW; Cheng HL; Bunkenborg J; Streeper RS; Mostoslavsky R; Kim J; Yancopoulos G; Valenzuela D; Murphy A; Yang Y; Chen Y; Hirschey MD; Bronson RT; Haigis M; Guarente LP; Farese RV; Weissman S; Verdin E; Schwer B
    Mol Cell Biol; 2007 Dec; 27(24):8807-14. PubMed ID: 17923681
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.
    Schlicker C; Gertz M; Papatheodorou P; Kachholz B; Becker CF; Steegborn C
    J Mol Biol; 2008 Oct; 382(3):790-801. PubMed ID: 18680753
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5.
    Nakamura Y; Ogura M; Tanaka D; Inagaki N
    Biochem Biophys Res Commun; 2008 Feb; 366(1):174-9. PubMed ID: 18054327
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes.
    Shi T; Wang F; Stieren E; Tong Q
    J Biol Chem; 2005 Apr; 280(14):13560-7. PubMed ID: 15653680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1.
    Sebaa R; Johnson J; Pileggi C; Norgren M; Xuan J; Sai Y; Tong Q; Krystkowiak I; Bondy-Chorney E; Davey NE; Krogan N; Downey M; Harper ME
    Mol Metab; 2019 Jul; 25():35-49. PubMed ID: 31060926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone H4 lysine 16 acetylation regulates cellular lifespan.
    Dang W; Steffen KK; Perry R; Dorsey JA; Johnson FB; Shilatifard A; Kaeberlein M; Kennedy BK; Berger SL
    Nature; 2009 Jun; 459(7248):802-7. PubMed ID: 19516333
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases.
    Khan AN; Lewis PN
    J Biol Chem; 2006 Apr; 281(17):11702-11. PubMed ID: 16520376
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
    Rardin MJ; Newman JC; Held JM; Cusack MP; Sorensen DJ; Li B; Schilling B; Mooney SD; Kahn CR; Verdin E; Gibson BW
    Proc Natl Acad Sci U S A; 2013 Apr; 110(16):6601-6. PubMed ID: 23576753
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
    Hirschey MD; Shimazu T; Goetzman E; Jing E; Schwer B; Lombard DB; Grueter CA; Harris C; Biddinger S; Ilkayeva OR; Stevens RD; Li Y; Saha AK; Ruderman NB; Bain JR; Newgard CB; Farese RV; Alt FW; Kahn CR; Verdin E
    Nature; 2010 Mar; 464(7285):121-5. PubMed ID: 20203611
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation.
    Lombard DB; Tishkoff DX; Bao J
    Handb Exp Pharmacol; 2011; 206():163-88. PubMed ID: 21879450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SIR2 modifies histone H4-K16 acetylation and affects superhelicity in the ARS region of plasmid chromatin in Saccharomyces cerevisiae.
    Chiani F; Di Felice F; Camilloni G
    Nucleic Acids Res; 2006; 34(19):5426-37. PubMed ID: 17012273
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase.
    Zhang Y; Bharathi SS; Rardin MJ; Uppala R; Verdin E; Gibson BW; Goetzman ES
    PLoS One; 2015; 10(3):e0122297. PubMed ID: 25811481
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress.
    Scher MB; Vaquero A; Reinberg D
    Genes Dev; 2007 Apr; 21(8):920-8. PubMed ID: 17437997
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Arabidopsis class II sirtuin is a lysine deacetylase and interacts with mitochondrial energy metabolism.
    König AC; Hartl M; Pham PA; Laxa M; Boersema PJ; Orwat A; Kalitventseva I; Plöchinger M; Braun HP; Leister D; Mann M; Wachter A; Fernie AR; Finkemeier I
    Plant Physiol; 2014 Mar; 164(3):1401-14. PubMed ID: 24424322
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.
    Tsuchiya M; Dang N; Kerr EO; Hu D; Steffen KK; Oakes JA; Kennedy BK; Kaeberlein M
    Aging Cell; 2006 Dec; 5(6):505-14. PubMed ID: 17129213
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The human SIRT3 protein deacetylase is exclusively mitochondrial.
    Cooper HM; Spelbrink JN
    Biochem J; 2008 Apr; 411(2):279-85. PubMed ID: 18215119
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria.
    Onyango P; Celic I; McCaffery JM; Boeke JD; Feinberg AP
    Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13653-8. PubMed ID: 12374852
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitochondrial sirtuins.
    Huang JY; Hirschey MD; Shimazu T; Ho L; Verdin E
    Biochim Biophys Acta; 2010 Aug; 1804(8):1645-51. PubMed ID: 20060508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis.
    Ahn BH; Kim HS; Song S; Lee IH; Liu J; Vassilopoulos A; Deng CX; Finkel T
    Proc Natl Acad Sci U S A; 2008 Sep; 105(38):14447-52. PubMed ID: 18794531
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry.
    Sauve AA; Schramm VL
    Biochemistry; 2003 Aug; 42(31):9249-56. PubMed ID: 12899610
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 58.