218 related articles for article (PubMed ID: 17925401)
1. An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance.
Lee OH; Jain AK; Papusha V; Jaiswal AK
J Biol Chem; 2007 Dec; 282(50):36412-20. PubMed ID: 17925401
[TBL] [Abstract][Full Text] [Related]
2. Nrf2 signaling and cell survival.
Niture SK; Kaspar JW; Shen J; Jaiswal AK
Toxicol Appl Pharmacol; 2010 Apr; 244(1):37-42. PubMed ID: 19538984
[TBL] [Abstract][Full Text] [Related]
3. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
Kaspar JW; Niture SK; Jaiswal AK
J Cell Sci; 2012 Feb; 125(Pt 4):1027-38. PubMed ID: 22448038
[TBL] [Abstract][Full Text] [Related]
4. An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.
Kaspar JW; Jaiswal AK
J Biol Chem; 2010 Jul; 285(28):21349-58. PubMed ID: 20452971
[TBL] [Abstract][Full Text] [Related]
5. Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance.
Niture SK; Jain AK; Jaiswal AK
J Cell Sci; 2009 Dec; 122(Pt 24):4452-64. PubMed ID: 19920073
[TBL] [Abstract][Full Text] [Related]
6. Regulation of Nrf2-an update.
Niture SK; Khatri R; Jaiswal AK
Free Radic Biol Med; 2014 Jan; 66():36-44. PubMed ID: 23434765
[TBL] [Abstract][Full Text] [Related]
7. Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2.
Niture SK; Jaiswal AK
J Biol Chem; 2009 May; 284(20):13856-13868. PubMed ID: 19279002
[TBL] [Abstract][Full Text] [Related]
8. Aromatase Inhibitor-Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer.
Khatri R; Shah P; Guha R; Rassool FV; Tomkinson AE; Brodie A; Jaiswal AK
Mol Cancer Ther; 2015 Jul; 14(7):1728-37. PubMed ID: 25976679
[TBL] [Abstract][Full Text] [Related]
9. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
Sun Z; Zhang S; Chan JY; Zhang DD
Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
[TBL] [Abstract][Full Text] [Related]
10. Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression.
Bloom DA; Jaiswal AK
J Biol Chem; 2003 Nov; 278(45):44675-82. PubMed ID: 12947090
[TBL] [Abstract][Full Text] [Related]
11. Hsp90 interaction with INrf2(Keap1) mediates stress-induced Nrf2 activation.
Niture SK; Jaiswal AK
J Biol Chem; 2010 Nov; 285(47):36865-75. PubMed ID: 20864537
[TBL] [Abstract][Full Text] [Related]
12. Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.
Dhakshinamoorthy S; Jaiswal AK
Oncogene; 2001 Jun; 20(29):3906-17. PubMed ID: 11439354
[TBL] [Abstract][Full Text] [Related]
13. Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance.
Niture SK; Jaiswal AK
Free Radic Biol Med; 2013 Apr; 57():119-31. PubMed ID: 23275004
[TBL] [Abstract][Full Text] [Related]
14. Oncogene PKCĪµ controls INrf2-Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2.
Niture SK; Gnatt A; Jaiswal AK
J Cell Sci; 2013 Dec; 126(Pt 24):5657-69. PubMed ID: 24127568
[TBL] [Abstract][Full Text] [Related]
15. Nrf2:INrf2 (Keap1) signaling in oxidative stress.
Kaspar JW; Niture SK; Jaiswal AK
Free Radic Biol Med; 2009 Nov; 47(9):1304-9. PubMed ID: 19666107
[TBL] [Abstract][Full Text] [Related]
16. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2: a novel mechanism in Nrf2 activation.
Jain AK; Mahajan S; Jaiswal AK
J Biol Chem; 2008 Jun; 283(25):17712-20. PubMed ID: 18434303
[TBL] [Abstract][Full Text] [Related]
17. Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2.
Sekhar KR; Yan XX; Freeman ML
Oncogene; 2002 Oct; 21(44):6829-34. PubMed ID: 12360409
[TBL] [Abstract][Full Text] [Related]
18. INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis.
Niture SK; Jaiswal AK
Cell Death Differ; 2011 Mar; 18(3):439-51. PubMed ID: 20865015
[TBL] [Abstract][Full Text] [Related]
19. Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
Habib E; Linher-Melville K; Lin HX; Singh G
Redox Biol; 2015 Aug; 5():33-42. PubMed ID: 25827424
[TBL] [Abstract][Full Text] [Related]
20. Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression.
Kaspar JW; Jaiswal AK
J Biol Chem; 2010 Jan; 285(1):153-62. PubMed ID: 19897490
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]