BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 17927164)

  • 1. Development of novel enkephalin analogues that have enhanced opioid activities at both mu and delta opioid receptors.
    Lee YS; Petrov R; Park CK; Ma SW; Davis P; Lai J; Porreca F; Vardanyan R; Hruby VJ
    J Med Chem; 2007 Nov; 50(22):5528-32. PubMed ID: 17927164
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
    Ananthan S; Johnson CA; Carter RL; Clayton SD; Rice KC; Xu H; Davis P; Porreca F; Rothman RB
    J Med Chem; 1998 Jul; 41(15):2872-81. PubMed ID: 9667975
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
    Salvadori S; Balboni G; Guerrini R; Tomatis R; Bianchi C; Bryant SD; Cooper PS; Lazarus LH
    J Med Chem; 1997 Sep; 40(19):3100-8. PubMed ID: 9301674
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
    Yamamoto T; Nair P; Vagner J; Largent-Milnes T; Davis P; Ma SW; Navratilova E; Moye S; Tumati S; Lai J; Yamamura HI; Vanderah TW; Porreca F; Hruby VJ
    J Med Chem; 2008 Mar; 51(5):1369-76. PubMed ID: 18266313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands.
    Rew Y; Malkmus S; Svensson C; Yaksh TL; Chung NN; Schiller PW; Cassel JA; DeHaven RN; Taulane JP; Goodman M
    J Med Chem; 2002 Aug; 45(17):3746-54. PubMed ID: 12166947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of potent μ and δ opioid agonists with high lipophilicity.
    Lee YS; Kulkarani V; Cowell SM; Ma SW; Davis P; Hanlon KE; Vanderah TW; Lai J; Porreca F; Vardanyan R; Hruby VJ
    J Med Chem; 2011 Jan; 54(1):382-6. PubMed ID: 21128594
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.
    Agnes RS; Lee YS; Davis P; Ma SW; Badghisi H; Porreca F; Lai J; Hruby VJ
    J Med Chem; 2006 May; 49(10):2868-75. PubMed ID: 16686530
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations.
    Deekonda S; Cole J; Sunna S; Rankin D; Largent-Milnes TM; Davis P; BassiriRad NM; Lai J; Vanderah TW; Porecca F; Hruby VJ
    Bioorg Med Chem Lett; 2016 Jan; 26(1):222-7. PubMed ID: 26611918
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Potent Dmt-Tic pharmacophoric delta- and mu-opioid receptor antagonists.
    Li T; Fujita Y; Shiotani K; Miyazaki A; Tsuda Y; Ambo A; Sasaki Y; Jinsmaa Y; Marczak E; Bryant SD; Salvadori S; Lazarus LH; Okada Y
    J Med Chem; 2005 Dec; 48(25):8035-44. PubMed ID: 16335927
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.
    Li T; Shiotani K; Miyazaki A; Tsuda Y; Ambo A; Sasaki Y; Jinsmaa Y; Marczak E; Bryant SD; Lazarus LH; Okada Y
    J Med Chem; 2007 Jun; 50(12):2753-66. PubMed ID: 17497839
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Opioid profiles of Cys2-containing enkephalin analogues.
    Pencheva N; Milanov P; Vezenkov L; Pajpanova T; Naydenova E
    Eur J Pharmacol; 2004 Sep; 498(1-3):249-56. PubMed ID: 15364002
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dicarba analogues of the cyclic enkephalin peptides H-Tyr-c[D-Cys-Gly-Phe-D(or L)-Cys]NH(2) retain high opioid activity.
    Berezowska I; Chung NN; Lemieux C; Wilkes BC; Schiller PW
    J Med Chem; 2007 Mar; 50(6):1414-7. PubMed ID: 17315860
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of stable and potent delta/mu opioid peptides: analogues of H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-OH by ring-closing metathesis.
    Mollica A; Guardiani G; Davis P; Ma SW; Porreca F; Lai J; Mannina L; Sobolev AP; Hruby VJ
    J Med Chem; 2007 Jun; 50(13):3138-42. PubMed ID: 17539621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cis-4-amino-L-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues.
    Mollica A; Pinnen F; Stefanucci A; Feliciani F; Campestre C; Mannina L; Sobolev AP; Lucente G; Davis P; Lai J; Ma SW; Porreca F; Hruby VJ
    J Med Chem; 2012 Apr; 55(7):3027-35. PubMed ID: 22394120
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.
    Yamamoto T; Nair P; Davis P; Ma SW; Navratilova E; Moye S; Tumati S; Lai J; Vanderah TW; Yamamura HI; Porreca F; Hruby VJ
    J Med Chem; 2007 Jun; 50(12):2779-86. PubMed ID: 17516639
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of potent bifunctional endomorphin-2 analogues with mixed mu-/delta-opioid agonist and delta-opioid antagonist properties.
    Fujita Y; Tsuda Y; Li T; Motoyama T; Takahashi M; Shimizu Y; Yokoi T; Sasaki Y; Ambo A; Kita A; Jinsmaa Y; Bryant SD; Lazarus LH; Okada Y
    J Med Chem; 2004 Jul; 47(14):3591-9. PubMed ID: 15214786
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists.
    Tóth G; Ioja E; Tömböly C; Ballet S; Tourwé D; Péter A; Martinek T; Chung NN; Schiller PW; Benyhe S; Borsodi A
    J Med Chem; 2007 Jan; 50(2):328-33. PubMed ID: 17228874
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence for lack of modulation of mu-opioid agonist action by delta-opioid agonists in the mouse vas deferens and guinea-pig ileum.
    Elliott J; Traynor JR
    Br J Pharmacol; 1995 Mar; 114(5):1064-8. PubMed ID: 7780641
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of novel hydrazide-linked bifunctional peptides as delta/mu opioid receptor agonists and CCK-1/CCK-2 receptor antagonists.
    Lee YS; Agnes RS; Badghisi H; Davis P; Ma SW; Lai J; Porreca F; Hruby VJ
    J Med Chem; 2006 Mar; 49(5):1773-80. PubMed ID: 16509592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.
    McLamore S; Ullrich T; Rothman RB; Xu H; Dersch C; Coop A; Davis P; Porreca F; Jacobson AE; Rice KC
    J Med Chem; 2001 Apr; 44(9):1471-4. PubMed ID: 11311071
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.