107 related articles for article (PubMed ID: 17928366)
21. The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.
Yamashita S; Tai P; Charron J; Ko C; Ascoli M
Mol Endocrinol; 2011 Jul; 25(7):1211-22. PubMed ID: 21527500
[TBL] [Abstract][Full Text] [Related]
22. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.
Voisin L; Julien C; Duhamel S; Gopalbhai K; Claveau I; Saba-El-Leil MK; Rodrigue-Gervais IG; Gaboury L; Lamarre D; Basik M; Meloche S
BMC Cancer; 2008 Nov; 8():337. PubMed ID: 19014680
[TBL] [Abstract][Full Text] [Related]
23. The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions.
Whitehurst AW; Robinson FL; Moore MS; Cobb MH
J Biol Chem; 2004 Mar; 279(13):12840-7. PubMed ID: 14707138
[TBL] [Abstract][Full Text] [Related]
24. Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.
Aoidi R; Maltais A; Charron J
Sci Signal; 2016 Jan; 9(412):ra9. PubMed ID: 26814233
[TBL] [Abstract][Full Text] [Related]
25. The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2.
Bardwell AJ; Lagunes L; Zebarjedi R; Bardwell L
J Biol Chem; 2017 May; 292(21):8750-8761. PubMed ID: 28396345
[TBL] [Abstract][Full Text] [Related]
26. [Mek1 and Mek2 functions in the formation of the blood placental barrier].
Nadeau V; Bissonauth V; Charron J
Med Sci (Paris); 2012 Apr; 28(4):409-15. PubMed ID: 22549869
[TBL] [Abstract][Full Text] [Related]
27. MEK1 and MEK2 differentially control the duration and amplitude of the ERK cascade response.
Kocieniewski P; Lipniacki T
Phys Biol; 2013 Jun; 10(3):035006. PubMed ID: 23735655
[TBL] [Abstract][Full Text] [Related]
28. Extracellular signal-regulated kinase 2 (ERK2) phosphorylation sites and docking domain on the nuclear pore complex protein Tpr cooperatively regulate ERK2-Tpr interaction.
Vomastek T; Iwanicki MP; Burack WR; Tiwari D; Kumar D; Parsons JT; Weber MJ; Nandicoori VK
Mol Cell Biol; 2008 Nov; 28(22):6954-66. PubMed ID: 18794356
[TBL] [Abstract][Full Text] [Related]
29. MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.
Caunt CJ; Sale MJ; Smith PD; Cook SJ
Nat Rev Cancer; 2015 Oct; 15(10):577-92. PubMed ID: 26399658
[TBL] [Abstract][Full Text] [Related]
30. Novel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms.
Sipieter F; Cappe B; Gonzalez Pisfil M; Spriet C; Bodart JF; Cailliau-Maggio K; Vandenabeele P; Héliot L; Riquet FB
PLoS One; 2015; 10(10):e0140924. PubMed ID: 26517832
[TBL] [Abstract][Full Text] [Related]
31. MEK1 and MEK2 differentially regulate human insulin- and insulin glargine-induced human bladder cancer T24 cell proliferation.
Liu SY; Liang Y; Lin TX; Su F; Liang WW; Uwe H; Li Y
Chin Med J (Engl); 2012 Dec; 125(23):4197-201. PubMed ID: 23217386
[TBL] [Abstract][Full Text] [Related]
32. Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.
McReynolds AC; Karra AS; Li Y; Lopez ED; Turjanski AG; Dioum E; Lorenz K; Zaganjor E; Stippec S; McGlynn K; Earnest S; Cobb MH
Biochemistry; 2016 Mar; 55(12):1909-17. PubMed ID: 26950759
[TBL] [Abstract][Full Text] [Related]
33. Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression.
Chen T; Yang M; Yu Z; Tang S; Wang C; Zhu X; Guo J; Li N; Zhang W; Hou J; Liu H; Han C; Liu Q; Gu Y; Qian C; Wan T; Cui L; Zhu M; Zheng W; Cao X
Cancer Cell; 2014 May; 25(5):682-96. PubMed ID: 24746703
[TBL] [Abstract][Full Text] [Related]
34. Live Cell Imaging of ERK and MEK: simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK.
Burack WR; Shaw AS
J Biol Chem; 2005 Feb; 280(5):3832-7. PubMed ID: 15546878
[TBL] [Abstract][Full Text] [Related]
35. Identification of a cytoplasmic-retention sequence in ERK2.
Rubinfeld H; Hanoch T; Seger R
J Biol Chem; 1999 Oct; 274(43):30349-52. PubMed ID: 10521408
[TBL] [Abstract][Full Text] [Related]
36. Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking.
Xu Be ; Stippec S; Robinson FL; Cobb MH
J Biol Chem; 2001 Jul; 276(28):26509-15. PubMed ID: 11352917
[TBL] [Abstract][Full Text] [Related]
37. Implication of MEK1 and MEK2 in the establishment of the blood-placenta barrier during placentogenesis in mouse.
Charron J; Bissonauth V; Nadeau V
Reprod Biomed Online; 2012 Jul; 25(1):58-67. PubMed ID: 22561024
[TBL] [Abstract][Full Text] [Related]
38. Expression, purification and characterization of inactive and active forms of ERK2 from insect expression system.
Yan K; Merritt H; Crawford K; Pardee G; Cheng JM; Widger S; Hekmat-Nejad M; Zaror I; Sim J
Protein Expr Purif; 2015 Jun; 110():172-9. PubMed ID: 25818999
[TBL] [Abstract][Full Text] [Related]
39. Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis.
Procaccia S; Ordan M; Cohen I; Bendetz-Nezer S; Seger R
Sci Rep; 2017 Feb; 7():43078. PubMed ID: 28225038
[TBL] [Abstract][Full Text] [Related]
40. How activating mutations affect MEK1 regulation and function.
Jindal GA; Goyal Y; Humphreys JM; Yeung E; Tian K; Patterson VL; He H; Burdine RD; Goldsmith EJ; Shvartsman SY
J Biol Chem; 2017 Nov; 292(46):18814-18820. PubMed ID: 29018093
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]