These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 17928366)

  • 21. The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.
    Yamashita S; Tai P; Charron J; Ko C; Ascoli M
    Mol Endocrinol; 2011 Jul; 25(7):1211-22. PubMed ID: 21527500
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.
    Voisin L; Julien C; Duhamel S; Gopalbhai K; Claveau I; Saba-El-Leil MK; Rodrigue-Gervais IG; Gaboury L; Lamarre D; Basik M; Meloche S
    BMC Cancer; 2008 Nov; 8():337. PubMed ID: 19014680
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions.
    Whitehurst AW; Robinson FL; Moore MS; Cobb MH
    J Biol Chem; 2004 Mar; 279(13):12840-7. PubMed ID: 14707138
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.
    Aoidi R; Maltais A; Charron J
    Sci Signal; 2016 Jan; 9(412):ra9. PubMed ID: 26814233
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2.
    Bardwell AJ; Lagunes L; Zebarjedi R; Bardwell L
    J Biol Chem; 2017 May; 292(21):8750-8761. PubMed ID: 28396345
    [TBL] [Abstract][Full Text] [Related]  

  • 26. [Mek1 and Mek2 functions in the formation of the blood placental barrier].
    Nadeau V; Bissonauth V; Charron J
    Med Sci (Paris); 2012 Apr; 28(4):409-15. PubMed ID: 22549869
    [TBL] [Abstract][Full Text] [Related]  

  • 27. MEK1 and MEK2 differentially control the duration and amplitude of the ERK cascade response.
    Kocieniewski P; Lipniacki T
    Phys Biol; 2013 Jun; 10(3):035006. PubMed ID: 23735655
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Extracellular signal-regulated kinase 2 (ERK2) phosphorylation sites and docking domain on the nuclear pore complex protein Tpr cooperatively regulate ERK2-Tpr interaction.
    Vomastek T; Iwanicki MP; Burack WR; Tiwari D; Kumar D; Parsons JT; Weber MJ; Nandicoori VK
    Mol Cell Biol; 2008 Nov; 28(22):6954-66. PubMed ID: 18794356
    [TBL] [Abstract][Full Text] [Related]  

  • 29. MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.
    Caunt CJ; Sale MJ; Smith PD; Cook SJ
    Nat Rev Cancer; 2015 Oct; 15(10):577-92. PubMed ID: 26399658
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Novel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms.
    Sipieter F; Cappe B; Gonzalez Pisfil M; Spriet C; Bodart JF; Cailliau-Maggio K; Vandenabeele P; Héliot L; Riquet FB
    PLoS One; 2015; 10(10):e0140924. PubMed ID: 26517832
    [TBL] [Abstract][Full Text] [Related]  

  • 31. MEK1 and MEK2 differentially regulate human insulin- and insulin glargine-induced human bladder cancer T24 cell proliferation.
    Liu SY; Liang Y; Lin TX; Su F; Liang WW; Uwe H; Li Y
    Chin Med J (Engl); 2012 Dec; 125(23):4197-201. PubMed ID: 23217386
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.
    McReynolds AC; Karra AS; Li Y; Lopez ED; Turjanski AG; Dioum E; Lorenz K; Zaganjor E; Stippec S; McGlynn K; Earnest S; Cobb MH
    Biochemistry; 2016 Mar; 55(12):1909-17. PubMed ID: 26950759
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression.
    Chen T; Yang M; Yu Z; Tang S; Wang C; Zhu X; Guo J; Li N; Zhang W; Hou J; Liu H; Han C; Liu Q; Gu Y; Qian C; Wan T; Cui L; Zhu M; Zheng W; Cao X
    Cancer Cell; 2014 May; 25(5):682-96. PubMed ID: 24746703
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Live Cell Imaging of ERK and MEK: simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK.
    Burack WR; Shaw AS
    J Biol Chem; 2005 Feb; 280(5):3832-7. PubMed ID: 15546878
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of a cytoplasmic-retention sequence in ERK2.
    Rubinfeld H; Hanoch T; Seger R
    J Biol Chem; 1999 Oct; 274(43):30349-52. PubMed ID: 10521408
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking.
    Xu Be ; Stippec S; Robinson FL; Cobb MH
    J Biol Chem; 2001 Jul; 276(28):26509-15. PubMed ID: 11352917
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Implication of MEK1 and MEK2 in the establishment of the blood-placenta barrier during placentogenesis in mouse.
    Charron J; Bissonauth V; Nadeau V
    Reprod Biomed Online; 2012 Jul; 25(1):58-67. PubMed ID: 22561024
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Expression, purification and characterization of inactive and active forms of ERK2 from insect expression system.
    Yan K; Merritt H; Crawford K; Pardee G; Cheng JM; Widger S; Hekmat-Nejad M; Zaror I; Sim J
    Protein Expr Purif; 2015 Jun; 110():172-9. PubMed ID: 25818999
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis.
    Procaccia S; Ordan M; Cohen I; Bendetz-Nezer S; Seger R
    Sci Rep; 2017 Feb; 7():43078. PubMed ID: 28225038
    [TBL] [Abstract][Full Text] [Related]  

  • 40. How activating mutations affect MEK1 regulation and function.
    Jindal GA; Goyal Y; Humphreys JM; Yeung E; Tian K; Patterson VL; He H; Burdine RD; Goldsmith EJ; Shvartsman SY
    J Biol Chem; 2017 Nov; 292(46):18814-18820. PubMed ID: 29018093
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.