126 related articles for article (PubMed ID: 17932038)
1. Controlled concealment of exposed clearance and immunogenic domains by site-specific polyethylene glycol attachment to acetylcholinesterase hypolysine mutants.
Cohen O; Kronman C; Lazar A; Velan B; Shafferman A
J Biol Chem; 2007 Dec; 282(49):35491-501. PubMed ID: 17932038
[TBL] [Abstract][Full Text] [Related]
2. Next generation OP-bioscavengers: a circulatory long-lived 4-PEG hypolysine mutant of F338A-HuAChE with optimal pharmacokinetics and pseudo-catalytic characteristics.
Kronman C; Cohen O; Mazor O; Ordentlich A; Raveh L; Velan B; Shafferman A
Chem Biol Interact; 2010 Sep; 187(1-3):253-8. PubMed ID: 20005217
[TBL] [Abstract][Full Text] [Related]
3. Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase.
Mazor O; Cohen O; Kronman C; Raveh L; Stein D; Ordentlich A; Shafferman A
Mol Pharmacol; 2008 Sep; 74(3):755-63. PubMed ID: 18523134
[TBL] [Abstract][Full Text] [Related]
4. Polyethylene-glycol conjugated recombinant human acetylcholinesterase serves as an efficacious bioscavenger against soman intoxication.
Kronman C; Cohen O; Raveh L; Mazor O; Ordentlich A; Shafferman A
Toxicology; 2007 Apr; 233(1-3):40-6. PubMed ID: 17045722
[TBL] [Abstract][Full Text] [Related]
5. Effect of chemical modification of recombinant human acetylcholinesterase by polyethylene glycol on its circulatory longevity.
Cohen O; Kronman C; Chitlaru T; Ordentlich A; Velan B; Shafferman A
Biochem J; 2001 Aug; 357(Pt 3):795-802. PubMed ID: 11463350
[TBL] [Abstract][Full Text] [Related]
6. Amino acid domains control the circulatory residence time of primate acetylcholinesterases in rhesus macaques (Macaca mulatta).
Cohen O; Kronman C; Velan B; Shafferman A
Biochem J; 2004 Feb; 378(Pt 1):117-28. PubMed ID: 14575524
[TBL] [Abstract][Full Text] [Related]
7. Comparison of polyethylene glycol-conjugated recombinant human acetylcholinesterase and serum human butyrylcholinesterase as bioscavengers of organophosphate compounds.
Cohen O; Kronman C; Raveh L; Mazor O; Ordentlich A; Shafferman A
Mol Pharmacol; 2006 Sep; 70(3):1121-31. PubMed ID: 16801396
[TBL] [Abstract][Full Text] [Related]
8. Acetylcholinesterase-Fc Fusion Protein (AChE-Fc): A Novel Potential Organophosphate Bioscavenger with Extended Plasma Half-Life.
Noy-Porat T; Cohen O; Ehrlich S; Epstein E; Alcalay R; Mazor O
Bioconjug Chem; 2015 Aug; 26(8):1753-8. PubMed ID: 26121420
[TBL] [Abstract][Full Text] [Related]
9. Host-regulated disposition of mammalian AChEs.
Kronman C; Cohen O; Velan B; Shafferman A
Chem Biol Interact; 2005 Dec; 157-158():51-5. PubMed ID: 16289063
[TBL] [Abstract][Full Text] [Related]
10. Involvement of oligomerization, N-glycosylation and sialylation in the clearance of cholinesterases from the circulation.
Kronman C; Velan B; Marcus D; Ordentlich A; Reuveny S; Shafferman A
Biochem J; 1995 Nov; 311 ( Pt 3)(Pt 3):959-67. PubMed ID: 7487957
[TBL] [Abstract][Full Text] [Related]
11. Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol.
Hershfield MS; Chaffee S; Koro-Johnson L; Mary A; Smith AA; Short SA
Proc Natl Acad Sci U S A; 1991 Aug; 88(16):7185-9. PubMed ID: 1714590
[TBL] [Abstract][Full Text] [Related]
12. Impact of anti-PEG antibody affinity on accelerated blood clearance of pegylated epoetin beta in mice.
Chang TC; Chen BM; Wu JY; Cheng TL; Roffler S
Biomed Pharmacother; 2022 Feb; 146():112502. PubMed ID: 34891120
[TBL] [Abstract][Full Text] [Related]
13. Plasma clearance and immunologic properties of long-acting superoxide dismutase prepared using 35,000 to 120,000 dalton poly-ethylene glycol.
Saifer MG; Somack R; Williams LD
Adv Exp Med Biol; 1994; 366():377-87. PubMed ID: 7771266
[TBL] [Abstract][Full Text] [Related]
14. Polyethylene Glycol-Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart.
Ozer I; Kelly G; Gu R; Li X; Zakharov N; Sirohi P; Nair SK; Collier JH; Hershfield MS; Hucknall AM; Chilkoti A
Adv Sci (Weinh); 2022 Apr; 9(11):e2103672. PubMed ID: 35133079
[TBL] [Abstract][Full Text] [Related]
15. Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R.
Atsmon J; Brill-Almon E; Nadri-Shay C; Chertkoff R; Alon S; Shaikevich D; Volokhov I; Haim KY; Bartfeld D; Shulman A; Ruderfer I; Ben-Moshe T; Shilovitzky O; Soreq H; Shaaltiel Y
Toxicol Appl Pharmacol; 2015 Sep; 287(3):202-9. PubMed ID: 26051873
[TBL] [Abstract][Full Text] [Related]
16. Carbohydrate-mediated polyethylene glycol conjugation of TSH improves its pharmacological properties.
Park A; Honey DM; Hou L; Bird JJ; Zarazinski C; Searles M; Braithwaite C; Kingsbury JS; Kyazike J; Culm-Merdek K; Greene B; Stefano JE; Qiu H; McPherson JM; Pan CQ
Endocrinology; 2013 Mar; 154(3):1373-83. PubMed ID: 23389953
[TBL] [Abstract][Full Text] [Related]
17. Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol.
Katre NV
J Immunol; 1990 Jan; 144(1):209-13. PubMed ID: 2295792
[TBL] [Abstract][Full Text] [Related]
18. Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model.
Rosenberg YJ; Saxena A; Sun W; Jiang X; Chilukuri N; Luo C; Doctor BP; Lee KD
Chem Biol Interact; 2010 Sep; 187(1-3):279-86. PubMed ID: 20211615
[TBL] [Abstract][Full Text] [Related]
19. Monoclonal antibodies to fetal bovine serum acetylcholinesterase distinguish between acetylcholinesterases from ruminant and non-ruminant species.
Naik RS; Belinskaya T; Vinayaka CR; Saxena A
Chem Biol Interact; 2020 Oct; 330():109225. PubMed ID: 32795450
[TBL] [Abstract][Full Text] [Related]
20. Relationship between molecular mass and duration of activity of polyethylene glycol conjugated granulocyte colony-stimulating factor mutein.
Bowen S; Tare N; Inoue T; Yamasaki M; Okabe M; Horii I; Eliason JF
Exp Hematol; 1999 Mar; 27(3):425-32. PubMed ID: 10089904
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
