BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 17935745)

  • 1. Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2.
    Aleksunes LM; Slitt AL; Maher JM; Augustine LM; Goedken MJ; Chan JY; Cherrington NJ; Klaassen CD; Manautou JE
    Toxicol Appl Pharmacol; 2008 Jan; 226(1):74-83. PubMed ID: 17935745
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes.
    Reisman SA; Buckley DB; Tanaka Y; Klaassen CD
    Toxicol Appl Pharmacol; 2009 Apr; 236(1):109-14. PubMed ID: 19371629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes.
    Aleksunes LM; Campion SN; Goedken MJ; Manautou JE
    Toxicol Sci; 2008 Aug; 104(2):261-73. PubMed ID: 18468992
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice.
    Ghanem CI; Rudraiah S; Bataille AM; Vigo MB; Goedken MJ; Manautou JE
    Biochem Pharmacol; 2015 Apr; 94(3):203-11. PubMed ID: 25667042
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway.
    Maher JM; Dieter MZ; Aleksunes LM; Slitt AL; Guo G; Tanaka Y; Scheffer GL; Chan JY; Manautou JE; Chen Y; Dalton TP; Yamamoto M; Klaassen CD
    Hepatology; 2007 Nov; 46(5):1597-610. PubMed ID: 17668877
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway.
    Jiang YM; Wang Y; Tan HS; Yu T; Fan XM; Chen P; Zeng H; Huang M; Bi HC
    Acta Pharmacol Sin; 2016 Mar; 37(3):382-9. PubMed ID: 26806302
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Is nuclear factor erythroid 2-related factor 2 responsible for sex differences in susceptibility to acetaminophen-induced hepatotoxicity in mice?
    Rohrer PR; Rudraiah S; Goedken MJ; Manautou JE
    Drug Metab Dispos; 2014 Oct; 42(10):1663-74. PubMed ID: 25092713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride.
    Aleksunes LM; Slitt AM; Cherrington NJ; Thibodeau MS; Klaassen CD; Manautou JE
    Toxicol Sci; 2005 Jan; 83(1):44-52. PubMed ID: 15496496
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tanshinone IIA protects against acetaminophen-induced hepatotoxicity via activating the Nrf2 pathway.
    Wang W; Guan C; Sun X; Zhao Z; Li J; Fu X; Qiu Y; Huang M; Jin J; Huang Z
    Phytomedicine; 2016 Jun; 23(6):589-96. PubMed ID: 27161400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway.
    Zhang X; Wang T; Yang Y; Li R; Chen Y; Li R; Jiang X; Wang L
    Biomed Pharmacother; 2020 Oct; 130():110547. PubMed ID: 32777703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.
    Maher JM; Aleksunes LM; Dieter MZ; Tanaka Y; Peters JM; Manautou JE; Klaassen CD
    Toxicol Sci; 2008 Dec; 106(2):319-28. PubMed ID: 18757529
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system.
    Pang C; Zheng Z; Shi L; Sheng Y; Wei H; Wang Z; Ji L
    Free Radic Biol Med; 2016 Feb; 91():236-46. PubMed ID: 26721592
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of acetaminophen vehicle on regulation of transporter gene expression during hepatotoxicity.
    Aleksunes LM; Augustine LM; Cherrington NJ; Manautou JE
    J Toxicol Environ Health A; 2007 Nov; 70(21):1870-2. PubMed ID: 17934960
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice.
    Randle LE; Goldring CE; Benson CA; Metcalfe PN; Kitteringham NR; Park BK; Williams DP
    Toxicology; 2008 Jan; 243(3):249-60. PubMed ID: 18078705
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
    Ning C; Gao X; Wang C; Kong Y; Liu Z; Sun H; Sun P; Huo X; Ma X; Meng Q; Liu K
    Regul Toxicol Pharmacol; 2018 Oct; 98():58-68. PubMed ID: 30030101
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice.
    Reisman SA; Csanaky IL; Aleksunes LM; Klaassen CD
    Toxicol Sci; 2009 May; 109(1):31-40. PubMed ID: 19246624
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coordinated expression of multidrug resistance-associated proteins (Mrps) in mouse liver during toxicant-induced injury.
    Aleksunes LM; Scheffer GL; Jakowski AB; Pruimboom-Brees IM; Manautou JE
    Toxicol Sci; 2006 Feb; 89(2):370-9. PubMed ID: 16177239
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hepatoprotective Activity of Yellow Chinese Chive against Acetaminophen-Induced Acute Liver Injury via Nrf2 Signaling Pathway.
    Kawakami K; Moritani C; Hatanaka T; Suzaki E; Tsuboi S
    J Nutr Sci Vitaminol (Tokyo); 2020; 66(4):357-363. PubMed ID: 32863309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway.
    Kay HY; Kim YW; Ryu DH; Sung SH; Hwang SJ; Kim SG
    Br J Pharmacol; 2011 Aug; 163(8):1653-65. PubMed ID: 21039417
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes.
    Enomoto A; Itoh K; Nagayoshi E; Haruta J; Kimura T; O'Connor T; Harada T; Yamamoto M
    Toxicol Sci; 2001 Jan; 59(1):169-77. PubMed ID: 11134556
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.