BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

794 related articles for article (PubMed ID: 17936559)

  • 1. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 2. hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.
    Moumen A; Masterson P; O'Connor MJ; Jackson SP
    Cell; 2005 Dec; 123(6):1065-78. PubMed ID: 16360036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.
    Khoronenkova SV; Dianova II; Ternette N; Kessler BM; Parsons JL; Dianov GL
    Mol Cell; 2012 Mar; 45(6):801-13. PubMed ID: 22361354
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Wip1 phosphatase and Mdm2: cracking the "Wip" on p53 stability.
    Lu X; Nguyen TA; Zhang X; Donehower LA
    Cell Cycle; 2008 Jan; 7(2):164-8. PubMed ID: 18333294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.
    Spinnler C; Hedström E; Li H; de Lange J; Nikulenkov F; Teunisse AF; Verlaan-de Vries M; Grinkevich V; Jochemsen AG; Selivanova G
    Cell Death Differ; 2011 Nov; 18(11):1736-45. PubMed ID: 21546907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.
    Dornan D; Shimizu H; Mah A; Dudhela T; Eby M; O'rourke K; Seshagiri S; Dixit VM
    Science; 2006 Aug; 313(5790):1122-6. PubMed ID: 16931761
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
    Yoda A; Toyoshima K; Watanabe Y; Onishi N; Hazaka Y; Tsukuda Y; Tsukada J; Kondo T; Tanaka Y; Minami Y
    J Biol Chem; 2008 Jul; 283(27):18969-79. PubMed ID: 18482988
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
    Shreeram S; Hee WK; Demidov ON; Kek C; Yamaguchi H; Fornace AJ; Anderson CW; Appella E; Bulavin DV
    J Exp Med; 2006 Dec; 203(13):2793-9. PubMed ID: 17158963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Wip1 phosphatase modulates ATM-dependent signaling pathways.
    Shreeram S; Demidov ON; Hee WK; Yamaguchi H; Onishi N; Kek C; Timofeev ON; Dudgeon C; Fornace AJ; Anderson CW; Minami Y; Appella E; Bulavin DV
    Mol Cell; 2006 Sep; 23(5):757-64. PubMed ID: 16949371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.
    Batchelor E; Mock CS; Bhan I; Loewer A; Lahav G
    Mol Cell; 2008 May; 30(3):277-89. PubMed ID: 18471974
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.
    Cheng Q; Chen L; Li Z; Lane WS; Chen J
    EMBO J; 2009 Dec; 28(24):3857-67. PubMed ID: 19816404
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response.
    Zhang X; Lin L; Guo H; Yang J; Jones SN; Jochemsen A; Lu X
    Cancer Res; 2009 Oct; 69(20):7960-8. PubMed ID: 19808970
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
    Tang J; Agrawal T; Cheng Q; Qu L; Brewer MD; Chen J; Yang X
    PLoS One; 2013; 8(2):e55813. PubMed ID: 23405218
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
    Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
    Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
    Darlington Y; Nguyen TA; Moon SH; Herron A; Rao P; Zhu C; Lu X; Donehower LA
    Oncogene; 2012 Mar; 31(9):1155-65. PubMed ID: 21765465
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.
    Lu X; Nguyen TA; Donehower LA
    Cell Cycle; 2005 Aug; 4(8):1060-4. PubMed ID: 15970689
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.
    Moon SH; Lin L; Zhang X; Nguyen TA; Darlington Y; Waldman AS; Lu X; Donehower LA
    J Biol Chem; 2010 Apr; 285(17):12935-47. PubMed ID: 20118229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.
    Lu X; Nannenga B; Donehower LA
    Genes Dev; 2005 May; 19(10):1162-74. PubMed ID: 15870257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2A.
    Shouse GP; Nobumori Y; Panowicz MJ; Liu X
    Oncogene; 2011 Sep; 30(35):3755-65. PubMed ID: 21460856
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 40.