BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1008 related articles for article (PubMed ID: 17936559)

  • 21. p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program.
    Pang LY; Scott M; Hayward RL; Mohammed H; Whitelaw CB; Smith GC; Hupp TR
    Cell Cycle; 2011 Mar; 10(6):932-50. PubMed ID: 21368573
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.
    Winter M; Sombroek D; Dauth I; Moehlenbrink J; Scheuermann K; Crone J; Hofmann TG
    Nat Cell Biol; 2008 Jul; 10(7):812-24. PubMed ID: 18536714
    [TBL] [Abstract][Full Text] [Related]  

  • 23. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 24. HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response.
    Lim KH; Park JJ; Gu BH; Kim JO; Park SG; Baek KH
    Sci Rep; 2015 Aug; 5():12793. PubMed ID: 26238070
    [TBL] [Abstract][Full Text] [Related]  

  • 25. UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
    Zhang XW; Wang XF; Ni SJ; Qin W; Zhao LQ; Hua RX; Lu YW; Li J; Dimri GP; Guo WJ
    J Pathol; 2015 Mar; 235(4):656-67. PubMed ID: 25382750
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Polo-like kinase-1 phosphorylates MDM2 at Ser260 and stimulates MDM2-mediated p53 turnover.
    Dias SS; Hogan C; Ochocka AM; Meek DW
    FEBS Lett; 2009 Nov; 583(22):3543-8. PubMed ID: 19833129
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Phosphorylated Hsp27 activates ATM-dependent p53 signaling and mediates the resistance of MCF-7 cells to doxorubicin-induced apoptosis.
    Xu Y; Diao Y; Qi S; Pan X; Wang Q; Xin Y; Cao X; Ruan J; Zhao Z; Luo L; Liu C; Yin Z
    Cell Signal; 2013 May; 25(5):1176-85. PubMed ID: 23357534
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J; Ferguson D; Song H; Bassing C; Eckersdorff M; Alt FW; Xu Y
    Mol Cell Biol; 2005 Jan; 25(2):661-70. PubMed ID: 15632067
    [TBL] [Abstract][Full Text] [Related]  

  • 29. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
    Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
    Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
    [TBL] [Abstract][Full Text] [Related]  

  • 30. ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.
    Taira N; Yamamoto H; Yamaguchi T; Miki Y; Yoshida K
    J Biol Chem; 2010 Feb; 285(7):4909-19. PubMed ID: 19965871
    [TBL] [Abstract][Full Text] [Related]  

  • 31. HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations.
    Di Stefano V; Mattiussi M; Sacchi A; D'Orazi G
    FEBS Lett; 2005 Oct; 579(25):5473-80. PubMed ID: 16212962
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation.
    Hjerpe R; Aillet F; Lopitz-Otsoa F; Lang V; Torres-Ramos M; Farrás R; Hay RT; Rodríguez MS
    Int J Biochem Cell Biol; 2010 May; 42(5):725-35. PubMed ID: 20080206
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mechanism of p53 stabilization by ATM after DNA damage.
    Cheng Q; Chen J
    Cell Cycle; 2010 Feb; 9(3):472-8. PubMed ID: 20081365
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner.
    Esfandiari A; Hawthorne TA; Nakjang S; Lunec J
    Mol Cancer Ther; 2016 Mar; 15(3):379-91. PubMed ID: 26832796
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.
    Khosravi R; Maya R; Gottlieb T; Oren M; Shiloh Y; Shkedy D
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14973-7. PubMed ID: 10611322
    [TBL] [Abstract][Full Text] [Related]  

  • 36. PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
    Bernardi R; Scaglioni PP; Bergmann S; Horn HF; Vousden KH; Pandolfi PP
    Nat Cell Biol; 2004 Jul; 6(7):665-72. PubMed ID: 15195100
    [TBL] [Abstract][Full Text] [Related]  

  • 37. ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.
    Gannon HS; Woda BA; Jones SN
    Cancer Cell; 2012 May; 21(5):668-679. PubMed ID: 22624716
    [TBL] [Abstract][Full Text] [Related]  

  • 38. HEY1 functions are regulated by its phosphorylation at Ser-68.
    López-Mateo I; Arruabarrena-Aristorena A; Artaza-Irigaray C; López JA; Calvo E; Belandia B
    Biosci Rep; 2016 Jul; 36(3):. PubMed ID: 27129302
    [TBL] [Abstract][Full Text] [Related]  

  • 39. SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription.
    Pavithra L; Mukherjee S; Sreenath K; Kar S; Sakaguchi K; Roy S; Chattopadhyay S
    J Mol Biol; 2009 May; 388(4):691-702. PubMed ID: 19303885
    [TBL] [Abstract][Full Text] [Related]  

  • 40. PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway.
    Chen H; Han L; Tsai H; Wang Z; Wu Y; Duo Y; Cao W; Chen L; Tan Z; Xu N; Huang X; Zhuang J; Huang L
    Oncotarget; 2016 Dec; 7(50):83241-83257. PubMed ID: 27829214
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 51.