294 related articles for article (PubMed ID: 17939684)
1. The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases.
Yamaguchi H; Durell SR; Chatterjee DK; Anderson CW; Appella E
Biochemistry; 2007 Nov; 46(44):12594-603. PubMed ID: 17939684
[TBL] [Abstract][Full Text] [Related]
2. Substrate specificity of the human protein phosphatase 2Cdelta, Wip1.
Yamaguchi H; Minopoli G; Demidov ON; Chatterjee DK; Anderson CW; Durell SR; Appella E
Biochemistry; 2005 Apr; 44(14):5285-94. PubMed ID: 15807522
[TBL] [Abstract][Full Text] [Related]
3. Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cdelta, Wip1.
Yamaguchi H; Durell SR; Feng H; Bai Y; Anderson CW; Appella E
Biochemistry; 2006 Nov; 45(44):13193-202. PubMed ID: 17073441
[TBL] [Abstract][Full Text] [Related]
4. Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.
Lu X; Nguyen TA; Donehower LA
Cell Cycle; 2005 Aug; 4(8):1060-4. PubMed ID: 15970689
[TBL] [Abstract][Full Text] [Related]
5. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
Yoda A; Toyoshima K; Watanabe Y; Onishi N; Hazaka Y; Tsukuda Y; Tsukada J; Kondo T; Tanaka Y; Minami Y
J Biol Chem; 2008 Jul; 283(27):18969-79. PubMed ID: 18482988
[TBL] [Abstract][Full Text] [Related]
6. Probing protein phosphatase substrate binding: affinity pull-down of ILKAP phosphatase 2C with phosphopeptides.
Højlys-Larsen KB; Sørensen KK; Jensen KJ; Gammeltoft S
Mol Biosyst; 2012 Apr; 8(5):1452-60. PubMed ID: 22348942
[TBL] [Abstract][Full Text] [Related]
7. Wip1 phosphatase modulates ATM-dependent signaling pathways.
Shreeram S; Demidov ON; Hee WK; Yamaguchi H; Onishi N; Kek C; Timofeev ON; Dudgeon C; Fornace AJ; Anderson CW; Minami Y; Appella E; Bulavin DV
Mol Cell; 2006 Sep; 23(5):757-64. PubMed ID: 16949371
[TBL] [Abstract][Full Text] [Related]
8. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.
Lu X; Nannenga B; Donehower LA
Genes Dev; 2005 May; 19(10):1162-74. PubMed ID: 15870257
[TBL] [Abstract][Full Text] [Related]
9. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
Shreeram S; Hee WK; Demidov ON; Kek C; Yamaguchi H; Fornace AJ; Anderson CW; Appella E; Bulavin DV
J Exp Med; 2006 Dec; 203(13):2793-9. PubMed ID: 17158963
[TBL] [Abstract][Full Text] [Related]
10. Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase.
Fujimoto H; Onishi N; Kato N; Takekawa M; Xu XZ; Kosugi A; Kondo T; Imamura M; Oishi I; Yoda A; Minami Y
Cell Death Differ; 2006 Jul; 13(7):1170-80. PubMed ID: 16311512
[TBL] [Abstract][Full Text] [Related]
11. The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
Oliva-Trastoy M; Berthonaud V; Chevalier A; Ducrot C; Marsolier-Kergoat MC; Mann C; Leteurtre F
Oncogene; 2007 Mar; 26(10):1449-58. PubMed ID: 16936775
[TBL] [Abstract][Full Text] [Related]
12. Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition.
Macůrek L; Lindqvist A; Voets O; Kool J; Vos HR; Medema RH
Oncogene; 2010 Apr; 29(15):2281-91. PubMed ID: 20101220
[TBL] [Abstract][Full Text] [Related]
13. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
[TBL] [Abstract][Full Text] [Related]
14. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.
Brazina J; Svadlenka J; Macurek L; Andera L; Hodny Z; Bartek J; Hanzlikova H
Cell Cycle; 2015; 14(3):375-87. PubMed ID: 25659035
[TBL] [Abstract][Full Text] [Related]
15. Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.
Yoda A; Xu XZ; Onishi N; Toyoshima K; Fujimoto H; Kato N; Oishi I; Kondo T; Minami Y
J Biol Chem; 2006 Aug; 281(34):24847-62. PubMed ID: 16798742
[TBL] [Abstract][Full Text] [Related]
16. Wip1-dependent signaling pathways in health and diseases.
Zhu YH; Bulavin DV
Prog Mol Biol Transl Sci; 2012; 106():307-25. PubMed ID: 22340722
[TBL] [Abstract][Full Text] [Related]
17. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.
Spinnler C; Hedström E; Li H; de Lange J; Nikulenkov F; Teunisse AF; Verlaan-de Vries M; Grinkevich V; Jochemsen AG; Selivanova G
Cell Death Differ; 2011 Nov; 18(11):1736-45. PubMed ID: 21546907
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancers.
Yu E; Ahn YS; Jang SJ; Kim MJ; Yoon HS; Gong G; Choi J
Breast Cancer Res Treat; 2007 Mar; 101(3):269-78. PubMed ID: 16897432
[TBL] [Abstract][Full Text] [Related]
19. Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control.
Moon SH; Nguyen TA; Darlington Y; Lu X; Donehower LA
Cell Cycle; 2010 Jun; 9(11):2092-6. PubMed ID: 20495376
[TBL] [Abstract][Full Text] [Related]
20. A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.
Carlessi L; Buscemi G; Fontanella E; Delia D
Biochim Biophys Acta; 2010 Oct; 1803(10):1213-23. PubMed ID: 20599567
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]