These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 17940282)

  • 1. Three-dimensional reconstruction using transmission electron microscopy reveals a swollen, bell-shaped structure of transient receptor potential melastatin type 2 cation channel.
    Maruyama Y; Ogura T; Mio K; Kiyonaka S; Kato K; Mori Y; Sato C
    J Biol Chem; 2007 Dec; 282(51):36961-70. PubMed ID: 17940282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
    Fliegert R; Watt JM; Schöbel A; Rozewitz MD; Moreau C; Kirchberger T; Thomas MP; Sick W; Araujo AC; Harneit A; Potter BVL; Guse AH
    Biochem J; 2017 Jun; 474(13):2159-2175. PubMed ID: 28515263
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structures and gating mechanism of human TRPM2.
    Wang L; Fu TM; Zhou Y; Xia S; Greka A; Wu H
    Science; 2018 Dec; 362(6421):. PubMed ID: 30467180
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
    Huang Y; Winkler PA; Sun W; Lü W; Du J
    Nature; 2018 Oct; 562(7725):145-149. PubMed ID: 30250252
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn
    Sander S; Pick J; Gattkowski E; Fliegert R; Tidow H
    Protein Sci; 2022 Jun; 31(6):e4320. PubMed ID: 35634784
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket.
    Yu P; Liu Z; Yu X; Ye P; Liu H; Xue X; Yang L; Li Z; Wu Y; Fang C; Zhao YJ; Yang F; Luo JH; Jiang LH; Zhang L; Zhang L; Yang W
    Cell Rep; 2019 Jun; 27(12):3684-3695.e4. PubMed ID: 31216484
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2.
    Yu P; Xue X; Zhang J; Hu X; Wu Y; Jiang LH; Jin H; Luo J; Zhang L; Liu Z; Yang W
    J Gen Physiol; 2017 Feb; 149(2):219-235. PubMed ID: 28108595
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.
    Kühn FJ; Lückhoff A
    J Biol Chem; 2004 Nov; 279(45):46431-7. PubMed ID: 15347676
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity.
    Iordanov I; Mihályi C; Tóth B; Csanády L
    Elife; 2016 Jul; 5():. PubMed ID: 27383051
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose.
    Kühn FJ; Heiner I; Lückhoff A
    Pflugers Arch; 2005 Oct; 451(1):212-9. PubMed ID: 15952035
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate.
    Tóth B; Iordanov I; Csanády L
    J Gen Physiol; 2015 May; 145(5):419-30. PubMed ID: 25918360
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels.
    Perraud AL; Takanishi CL; Shen B; Kang S; Smith MK; Schmitz C; Knowles HM; Ferraris D; Li W; Zhang J; Stoddard BL; Scharenberg AM
    J Biol Chem; 2005 Feb; 280(7):6138-48. PubMed ID: 15561722
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Requirement for the N-terminal coiled-coil domain for expression and function, but not subunit interaction of, the ADPR-activated TRPM2 channel.
    Mei ZZ; Jiang LH
    J Membr Biol; 2009 Jul; 230(2):93-9. PubMed ID: 19652898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?
    Fliegert R; Riekehr WM; Guse AH
    Front Immunol; 2020; 11():2018. PubMed ID: 32903769
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
    Tóth B; Csanády L
    J Biol Chem; 2010 Sep; 285(39):30091-102. PubMed ID: 20650899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
    Yin Y; Wu M; Hsu AL; Borschel WF; Borgnia MJ; Lander GC; Lee SY
    Nat Commun; 2019 Aug; 10(1):3740. PubMed ID: 31431622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
    Perraud AL; Fleig A; Dunn CA; Bagley LA; Launay P; Schmitz C; Stokes AJ; Zhu Q; Bessman MJ; Penner R; Kinet JP; Scharenberg AM
    Nature; 2001 May; 411(6837):595-9. PubMed ID: 11385575
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of TRPM2 channel gating revealed by cryo-EM.
    Xia S; Wang L; Fu TM; Wu H
    FEBS J; 2019 Sep; 286(17):3333-3339. PubMed ID: 31144442
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR.
    Kühn FJP; Watt JM; Potter BVL; Lückhoff A
    Sci Rep; 2019 Mar; 9(1):4985. PubMed ID: 30899048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors.
    Scharenberg AM
    Pflugers Arch; 2005 Oct; 451(1):220-7. PubMed ID: 16001276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.